Grant List
Represents Grant table in the DB
GET /v1/grants?sort=-other_investigators
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=-other_investigators", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1419&sort=-other_investigators", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=2&sort=-other_investigators", "prev": null }, "data": [ { "type": "Grant", "id": "15943", "attributes": { "award_id": "1R13OD039737-01", "title": "Annual Symposium on Nonhuman Primates", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 44387, "first_name": "SIGE", "last_name": "ZOU", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-05-01", "end_date": "2028-04-30", "award_amount": 74999, "principal_investigator": { "id": 8251, "first_name": "Deborah H.", "last_name": "Fuller", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44388, "first_name": "Jon E", "last_name": "Levine", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44389, "first_name": "Corinna Nicole", "last_name": "Ross", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 799, "ror": "", "name": "UNIVERSITY OF WISCONSIN-MADISON", "address": "", "city": "", "state": "WI", "zip": "", "country": "United States", "approved": true }, "abstract": "With this R13 application, we request funding to support, in part, the costs for planning, publicizing, and hosting the 42nd, 43rd, and 44th Annual Symposia on Nonhuman Primate Models for AIDS. For more than four decades, this symposium has served as the premier scientific forum for the exchange of information, including new research findings and scientific perspectives, among HIV/AIDS investigators whose research includes studies in nonhuman primates (NHPs). Disseminating the latest research findings in NHP models of AIDS while also facilitating discussion and exchange of information between basic scientists and clinicians remains a priority, as do focusing on emerging technologies to accelerate translation of NHP studies into the clinic and engaging a broader and more diverse group of researchers in HIV/AIDS research in NHP models. This meeting, the only one of its kind in the world, convenes an international group of scientists whose research focuses on the study of natural and experimental immunodeficiency virus infections in NHPs, as well as on the development of novel therapeutics, prophylactic vaccines for HIV, and curative approaches. Emerging topics in related infectious diseases (such as COVID-19 pathogenesis, vaccines and treatment) may also be included. The seven National Primate Research Centers (NPRCs) host this meeting in rotation, and upcoming symposia hosts will be the Wisconsin (2025), Southwest (2026), and Washington (2027) NPRCs. We plan a hybrid format with most participants attending in person and others joining online to access oral and poster sessions. The conference will begin on day 1 with registration, a keynote address by a leading HIV/AIDS researcher, and an evening reception. The following two and a half days will include scientific presentations from invited speakers and accepted oral abstracts. Each symposium scientific committee will select session topics and speakers to highlight new and cutting-edge technologies in their respective fields. Each session will open with a 30-minute talk by an invited chair. Individuals whose abstracts are accepted for oral presentations will give the remaining session talks. A poster session will occur on the evening of day 2, and there will be a banquet on the evening of day 3. As is traditional for this symposium, the Journal of Medical Primatology will publish all poster and oral abstracts in a special issue. In partnership with the HIV Vaccine Trials Network (HVTN), the NHP AIDS Symposium will also host a pre-symposium meeting for early-stage investigators (ESI). This meeting will be open to the attendees of a linked ESI Conference the HVTN sponsors. ESI attendees and mentors will focus on grant writing, budgeting, and networking, and will participate in a Q&A with NIH Program Officers. We believe bringing together researchers from a variety of diverse backgrounds will generate future collaborations and scientific advances. Knowledge shared and gained at upcoming Annual Nonhuman Primate Models for AIDS Symposia will further the continued, effective use of NHP models to maintain long term control of HIV replication in the absence of antiretroviral therapy and to design interventions to prevent or eradicate HIV infection.", "keywords": [ "2019-nCoV", "AIDS Vaccines", "Acceleration", "Acquired Immunodeficiency Syndrome", "Address", "Applications Grants", "Budgets", "COVID-19 pathogenesis", "COVID-19 treatment", "COVID-19 vaccine", "Clinic", "Collaborations", "Communicable Diseases", "Development", "Disease", "Drug Delivery Systems", "Emerging Technologies", "Epidemic", "Fees", "Fostering", "Funding", "Future", "Generations", "Grant", "HIV", "HIV Infections", "HIV Vaccine Trials Network", "HIV vaccine", "HIV/AIDS", "Health", "Human", "Hybrids", "Immune response", "Immunologist", "Individual", "International", "Intervention", "Journals", "Knowledge", "Life", "Link", "Logistics", "Medical", "Mentors", "Mission", "Monkeypox", "Oral", "Participant", "Pathogenesis", "Persons", "Preventive vaccine", "Primates", "Publishing", "Research", "Research Personnel", "Resources", "Rotation", "SIV", "Scientific Advances and Accomplishments", "Scientist", "Technology", "Testing", "Translations", "United States National Institutes of Health", "Universities", "Viral reservoir", "Virus", "Virus Diseases", "Washington", "Wisconsin", "Writing", "Zika Virus", "Zoonoses", "antiretroviral therapy", "cost", "disability", "emerging virus", "experience", "falls", "global health", "immunodeficiency", "innovation", "meetings", "neutralizing antibody", "nonhuman primate", "nonhuman primate models", "novel therapeutics", "novel vaccines", "originality", "pandemic virus", "posters", "prevent", "programs", "response", "symposium", "therapy design", "tool" ], "approved": true } }, { "type": "Grant", "id": "15943", "attributes": { "award_id": "1R13OD039737-01", "title": "Annual Symposium on Nonhuman Primates", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 44387, "first_name": "SIGE", "last_name": "ZOU", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-05-01", "end_date": "2028-04-30", "award_amount": 74999, "principal_investigator": { "id": 8251, "first_name": "Deborah H.", "last_name": "Fuller", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44388, "first_name": "Jon E", "last_name": "Levine", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44389, "first_name": "Corinna Nicole", "last_name": "Ross", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 799, "ror": "", "name": "UNIVERSITY OF WISCONSIN-MADISON", "address": "", "city": "", "state": "WI", "zip": "", "country": "United States", "approved": true }, "abstract": "With this R13 application, we request funding to support, in part, the costs for planning, publicizing, and hosting the 42nd, 43rd, and 44th Annual Symposia on Nonhuman Primate Models for AIDS. For more than four decades, this symposium has served as the premier scientific forum for the exchange of information, including new research findings and scientific perspectives, among HIV/AIDS investigators whose research includes studies in nonhuman primates (NHPs). Disseminating the latest research findings in NHP models of AIDS while also facilitating discussion and exchange of information between basic scientists and clinicians remains a priority, as do focusing on emerging technologies to accelerate translation of NHP studies into the clinic and engaging a broader and more diverse group of researchers in HIV/AIDS research in NHP models. This meeting, the only one of its kind in the world, convenes an international group of scientists whose research focuses on the study of natural and experimental immunodeficiency virus infections in NHPs, as well as on the development of novel therapeutics, prophylactic vaccines for HIV, and curative approaches. Emerging topics in related infectious diseases (such as COVID-19 pathogenesis, vaccines and treatment) may also be included. The seven National Primate Research Centers (NPRCs) host this meeting in rotation, and upcoming symposia hosts will be the Wisconsin (2025), Southwest (2026), and Washington (2027) NPRCs. We plan a hybrid format with most participants attending in person and others joining online to access oral and poster sessions. The conference will begin on day 1 with registration, a keynote address by a leading HIV/AIDS researcher, and an evening reception. The following two and a half days will include scientific presentations from invited speakers and accepted oral abstracts. Each symposium scientific committee will select session topics and speakers to highlight new and cutting-edge technologies in their respective fields. Each session will open with a 30-minute talk by an invited chair. Individuals whose abstracts are accepted for oral presentations will give the remaining session talks. A poster session will occur on the evening of day 2, and there will be a banquet on the evening of day 3. As is traditional for this symposium, the Journal of Medical Primatology will publish all poster and oral abstracts in a special issue. In partnership with the HIV Vaccine Trials Network (HVTN), the NHP AIDS Symposium will also host a pre-symposium meeting for early-stage investigators (ESI). This meeting will be open to the attendees of a linked ESI Conference the HVTN sponsors. ESI attendees and mentors will focus on grant writing, budgeting, and networking, and will participate in a Q&A with NIH Program Officers. We believe bringing together researchers from a variety of diverse backgrounds will generate future collaborations and scientific advances. Knowledge shared and gained at upcoming Annual Nonhuman Primate Models for AIDS Symposia will further the continued, effective use of NHP models to maintain long term control of HIV replication in the absence of antiretroviral therapy and to design interventions to prevent or eradicate HIV infection.", "keywords": [ "2019-nCoV", "AIDS Vaccines", "Acceleration", "Acquired Immunodeficiency Syndrome", "Address", "Applications Grants", "Budgets", "COVID-19 pathogenesis", "COVID-19 treatment", "COVID-19 vaccine", "Clinic", "Collaborations", "Communicable Diseases", "Development", "Disease", "Drug Delivery Systems", "Emerging Technologies", "Epidemic", "Fees", "Fostering", "Funding", "Future", "Generations", "Grant", "HIV", "HIV Infections", "HIV Vaccine Trials Network", "HIV vaccine", "HIV/AIDS", "Health", "Human", "Hybrids", "Immune response", "Immunologist", "Individual", "International", "Intervention", "Journals", "Knowledge", "Life", "Link", "Logistics", "Medical", "Mentors", "Mission", "Monkeypox", "Oral", "Participant", "Pathogenesis", "Persons", "Preventive vaccine", "Primates", "Publishing", "Research", "Research Personnel", "Resources", "Rotation", "SIV", "Scientific Advances and Accomplishments", "Scientist", "Technology", "Testing", "Translations", "United States National Institutes of Health", "Universities", "Viral reservoir", "Virus", "Virus Diseases", "Washington", "Wisconsin", "Writing", "Zika Virus", "Zoonoses", "antiretroviral therapy", "cost", "disability", "emerging virus", "experience", "falls", "global health", "immunodeficiency", "innovation", "meetings", "neutralizing antibody", "nonhuman primate", "nonhuman primate models", "novel therapeutics", "novel vaccines", "originality", "pandemic virus", "posters", "prevent", "programs", "response", "symposium", "therapy design", "tool" ], "approved": true } }, { "type": "Grant", "id": "15938", "attributes": { "award_id": "3U01AI069911-20S3", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 276896, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15941", "attributes": { "award_id": "3U01AI069911-20S5", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 195343, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15936", "attributes": { "award_id": "3U01AI069911-20S1", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 317911, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15937", "attributes": { "award_id": "3U01AI069911-20S6", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 47470, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15940", "attributes": { "award_id": "3U01AI069911-20S4", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 747173, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15939", "attributes": { "award_id": "3U01AI069911-20S2", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 121192, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15940", "attributes": { "award_id": "3U01AI069911-20S4", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 747173, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } }, { "type": "Grant", "id": "15939", "attributes": { "award_id": "3U01AI069911-20S2", "title": "East Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 44382, "first_name": "JOANAD'ARC C", "last_name": "ROE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2025-06-01", "end_date": "2026-05-31", "award_amount": 121192, "principal_investigator": { "id": 44383, "first_name": "AGGREY SEMWENDERO", "last_name": "SEMEERE", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 44384, "first_name": "Kara Kay", "last_name": "Wools-Kaloustian", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 44385, "first_name": "CONSTANTIN THEODORE", "last_name": "YIANNOUTSOS", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3402, "ror": "", "name": "INDIANA UNIVERSITY INDIANAPOLIS", "address": "", "city": "", "state": "IN", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: Our primary goal continues to be the provision of answers to questions that clinicians, governments, programs and international organizations consider central to the evolution and sustainability of their long term HIV care and treatment strategies for achieving the UNAIDS 2030 targets of 95-95-95 in the midst of the SARS-CoV-2 pandemic and changes in public health funding priorities. Our central hypothesis is that retention in the HIV care cascade and treatment outcomes are influenced by patient-level demographic, clinical, developmental, and behavioral factors, as well as, factors within the ambient health care and broader contextual environment. We will leverage our strengths, including robust working relationships with HIV treatment programs, a substantial harmonized regional database, plus broad experience in sampling-based methodologies and novel analytical approaches. Over the course of this research we will: SA-1: Describe movement through the HIV care cascade with a focus on identifying broader and health care environment contextual factors that influence optimal retention in care and viral suppression, in the face of global disruption due to the COVID-19 pandemic and changes in donor funding priorities. The Post COVID-19 Double-Sampling Cohort (Post COVID) will address the impact of broader contextual factors (COVID-19) while the Telehealth and Structural Adaptations project will address the impact of health care structure. SA-2: Examine the impact of developmental stage and behavioral factors on retention in the cascade and subsequent outcomes. The multiregional Adolescent and Young Adult Network of IeDEA (AYANI) and regional Measuring Adverse Pregnancy and Newborn Congenital Outcomes (MANGO) cohorts will assess the impact of developmental stage on the cascade, while the Syndemics cohort will address the impact of mental health on the cascade.SA- 3: Examine the immediate and long-term outcomes of people diagnosed with Tuberculosis (TB) with a focus on identifying and addressing factors associated with patient outcomes. The multiregional TB Sentinel Research Network (TB-SRN) will focus on understanding TB outcomes and long-term pulmonary complications including associated factors. SA-4: Explore the use of new technologies, including eHealth and machine (deep) learning to diagnose and manage HIV-associated cancers with a focus on Kaposi’s Sarcoma (KS) and Cervical Cancer. The KS Project will assess implementation of a Dermatology Telehealth Program and the Cervical Cancer Project will assess the implementation of cervical image capture with machine learning for cancer diagnoses and management. SA-5: Examine the epidemiology of NCD comorbidities and ART complications with a focus on the oldest and youngest-age groups affected by HIV. The multi-regional Sentinel Research Network (SRN) will address non-communicable diseases in people living with HIV (PLHIV) > 40 years and the regional MANGO Cohort will address complications of ART/HIV exposure on HIV-Exposed Infants.", "keywords": [ "2019-nCoV", "AIDS related cancer", "Achievement", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent and Young Adult", "Affect", "Africa", "Behavioral", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical", "Clinic", "Clinical", "Collaborations", "Communities", "Country", "Data", "Data Sources", "Databases", "Dermatology", "Development", "Diagnosis", "Disease", "Environment", "Epidemiology", "Evolution", "Funding", "Gender", "Genetic", "Geography", "Goals", "Government", "Grant", "HIV", "HIV/AIDS", "Health", "Health Care", "Home", "Image", "Infant", "International", "Joints", "Kaposi Sarcoma", "Kenya", "Knowledge", "Learning", "Liver diseases", "Longevity", "Machine Learning", "Malignant Neoplasms", "Malignant neoplasm of cervix uteri", "Measures", "Mental Depression", "Mental Health", "Methodology", "Methods", "Movement", "Newborn Infant", "Operations Research", "Outcome", "Patient-Focused Outcomes", "Patients", "Persons", "Policies", "Pregnancy", "Public Health", "Research", "Resource-limited setting", "Risk Factors", "Sampling", "Sentinel", "Statistical Methods", "Structure", "Tanzania", "Technology", "Telemedicine", "Treatment outcome", "Tuberculosis", "Tuberculosis diagnosis", "Uganda", "United Nations", "Viral", "age group", "antiretroviral therapy", "cancer diagnosis", "cardiovascular risk factor", "care outcomes", "co-infection", "cohort", "comorbidity", "contextual factors", "eHealth", "experience", "implementation evaluation", "implementation research", "insight", "new technology", "novel", "post-COVID-19", "programs", "pulmonary", "scale up", "substance use", "syndemic", "telehealth", "tool", "treatment guidelines", "treatment program", "treatment strategy" ], "approved": true } } ], "meta": { "pagination": { "page": 1, "pages": 1419, "count": 14184 } } }