Represents Grant table in the DB

GET /v1/grants?sort=-abstract
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{
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        "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=-abstract",
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    "data": [
        {
            "type": "Grant",
            "id": "7574",
            "attributes": {
                "award_id": "5UG4LM012346-05",
                "title": "National Network of Libraries of Medicine Greater Midwest (Region 3)",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Library of Medicine (NLM)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 8207,
                        "first_name": "ALAN",
                        "last_name": "VANBIERVLIET",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2016-05-01",
                "end_date": "2022-04-30",
                "award_amount": 2279507,
                "principal_investigator": {
                    "id": 23373,
                    "first_name": "LINDA J",
                    "last_name": "WALTON",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 220,
                            "ror": "https://ror.org/036jqmy94",
                            "name": "University of Iowa",
                            "address": "",
                            "city": "",
                            "state": "IA",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 220,
                    "ror": "https://ror.org/036jqmy94",
                    "name": "University of Iowa",
                    "address": "",
                    "city": "",
                    "state": "IA",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant):This proposal describes how the Hardin Library for the Health Sciences (HLHS), University of Iowa will assist the National Network of Libraries of Medicine (NN/LM), a program of the National Library of Medicine (NLM) with its mission of advancing the progress of medicine and improving the health of the public by: 1) providing all U.S. health professionals with equal access to biomedical information and, 2) improving the public's access to information to enable them to make informed decisions about their health. Located within the Greater Midwest Region (GMR), the Hardin Library proposes to serve as the Regional Medical Library for one of the largest and most diverse regions in the Network using leadership, partnerships and innovations as the backbone of the network. The RML will actively involve network members in supporting the mission through training and awards. The GMR includes ten states: Iowa, Illinois, Indiana, Kentucky, Michigan, Minnesota, North Dakota, Ohio, South Dakota, and Wisconsin. All states in the Greater Midwest Region have pockets large and small of poverty and medically underserved areas in both urban and rural communities. With tools from the U.S. Census Bureau and the Health Resources and Services Administration (HRSA) we can now drill down to counties within states to help us to identify those areas that are economically and medically underserved and to target these communities in our outreach in order to improve their access to health and medical information. We are requesting $6.5 million over a 5-year period for this proposal.",
                "keywords": [
                    "Access to Information",
                    "Area",
                    "Award",
                    "Censuses",
                    "Communication",
                    "Communities",
                    "Community Health",
                    "County",
                    "Data",
                    "Disasters",
                    "Economics",
                    "Education",
                    "Education and Outreach",
                    "Emergency Situation",
                    "Ensure",
                    "Grant",
                    "Health",
                    "Health Professional",
                    "Health Resources",
                    "Health Science Library",
                    "Health Sciences",
                    "Healthcare",
                    "Illinois",
                    "Indiana",
                    "Individual",
                    "Information Resources",
                    "Internet",
                    "Interruption",
                    "Iowa",
                    "Kentucky",
                    "Knowledge",
                    "Leadership",
                    "Librarians",
                    "Libraries",
                    "Life Cycle Stages",
                    "Location",
                    "Medical",
                    "Medical Libraries",
                    "Medically Underserved Area",
                    "Medicine",
                    "Michigan",
                    "Midwestern United States",
                    "Minnesota",
                    "Mission",
                    "North Dakota",
                    "Ohio",
                    "Poverty",
                    "PubMed",
                    "Public Health",
                    "Readiness",
                    "Research Personnel",
                    "Resources",
                    "Rural Community",
                    "Services",
                    "South Dakota",
                    "Time",
                    "Training",
                    "United States Health Resources and Services Administration",
                    "United States National Library of Medicine",
                    "Universities",
                    "Vertebral column",
                    "Wisconsin",
                    "Work",
                    "community organizations",
                    "data management",
                    "health training",
                    "improved",
                    "innovation",
                    "medically underserved",
                    "member",
                    "outreach",
                    "peer networks",
                    "programs",
                    "response",
                    "skills",
                    "tool"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "7535",
            "attributes": {
                "award_id": "5UG4LM012340-05",
                "title": "Southeastern/Atlantic Regional Medical Library",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Library of Medicine (NLM)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 8207,
                        "first_name": "ALAN",
                        "last_name": "VANBIERVLIET",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2016-05-01",
                "end_date": "2021-07-15",
                "award_amount": 1749912,
                "principal_investigator": {
                    "id": 23338,
                    "first_name": "Mary Joan",
                    "last_name": "Tooey",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 793,
                            "ror": "",
                            "name": "UNIVERSITY OF MARYLAND BALTIMORE",
                            "address": "",
                            "city": "",
                            "state": "MD",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 793,
                    "ror": "",
                    "name": "UNIVERSITY OF MARYLAND BALTIMORE",
                    "address": "",
                    "city": "",
                    "state": "MD",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant): With 33 years of experience in providing the service, the Health Sciences and Human Services Library of the University of Maryland, Baltimore (UMB) seeks to continue a Regional Medical Library Program supporting the Southeastern/Atlantic Region. UMB proposes a systematic approach to the project by establishing a governance and feedback structure; cultivating a network that provides access to biomedical and health information to all; building capacity through training, exhibits, and funding of outreach; conducting continual assessment of the program; and cooperating with the other RMLs and national NN/LM Offices to reduce duplication of effort and emphasize regional expertise. The approach is integrated, with each area depending upon the other for success and feedback.",
                "keywords": [
                    "Access to Information",
                    "Advisory Committees",
                    "Area",
                    "Baltimore",
                    "Big Data",
                    "Communication",
                    "Disasters",
                    "Education",
                    "Education and Outreach",
                    "Emergency Situation",
                    "Ensure",
                    "Environment",
                    "Evaluation",
                    "Exhibits",
                    "Family",
                    "Feedback",
                    "Friends",
                    "Funding",
                    "Health",
                    "Health Professional",
                    "Health Sciences",
                    "Healthcare",
                    "Human",
                    "Information Networks",
                    "Information Specialists",
                    "Knowledge",
                    "Leadership",
                    "Library Associations",
                    "Library Services",
                    "Maryland",
                    "Medical Libraries",
                    "Medicine",
                    "Mission",
                    "Outcome",
                    "Pacific Northwest",
                    "Persons",
                    "Program Evaluation",
                    "Provider",
                    "Public Health",
                    "Research Personnel",
                    "Seasons",
                    "Services",
                    "Structure",
                    "System",
                    "Target Populations",
                    "Training",
                    "Universities",
                    "data management",
                    "education evaluation",
                    "experience",
                    "improved",
                    "member",
                    "operation",
                    "outreach",
                    "programs",
                    "success",
                    "support network",
                    "tool",
                    "training project"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "9474",
            "attributes": {
                "award_id": "7R01AI045818-21",
                "title": "RNA-dependent RNA Polymerase",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute of Allergy and Infectious Diseases (NIAID)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 6054,
                        "first_name": "Eun-Chung",
                        "last_name": "Park",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2019-09-01",
                "end_date": "2021-06-30",
                "award_amount": 311837,
                "principal_investigator": {
                    "id": 8755,
                    "first_name": "CRAIG E.",
                    "last_name": "CAMERON",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 817,
                            "ror": "",
                            "name": "UNIV OF NORTH CAROLINA CHAPEL HILL",
                            "address": "",
                            "city": "",
                            "state": "NC",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 817,
                    "ror": "",
                    "name": "UNIV OF NORTH CAROLINA CHAPEL HILL",
                    "address": "",
                    "city": "",
                    "state": "NC",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant): Using poliovirus (PV) and its RNA-dependent RNA polymerase (RdRp), 3Dpol, as our primary model system, we, our collaborators and other picorna virologists have made a very compelling case for RdRp fidelity and the corresponding genetic diversity of the viral population as contributors to viral pathogenesis and virulence. This relationship between viral genetic diversity and viral fitness established using the PV model has now been demonstrated for a variety of virus families. In addition, we have demonstrated that the rate of nucleotide addition can be tuned and contributes to viral genetic diversity and viral fitness. Therefore, the overarching hypothesis driving our studies is that mechanisms governing RdRp speed and fidelity can be targeted genetically and chemically for development of attenuated viruses and antiviral agents, respectively. If one is to harness the full therapeutic an prophylactic potential of modulated RdRp function, however, knowledge of the physical mechanism(s) controlling RdRp speed and fidelity is needed. One goal of this application is to test and to exploit a new model for nucleotide selection that we anticipate can be applied to any RdRp. Recombination is a major contributor to viral evolution, leading to the emergence of vaccine-resistant strains and expansion of virus host range. Unfortunately, we lack sufficient knowledge of the molecular mechanism of RNA virus recombination to prevent this process from thwarting vaccine development and long- term efficacy. Therefore, an understanding of recombination is of potentially broad, practical value. For example, detailed knowledge of the mechanism of recombination may establish principles that can be exploited for development of strategies to suppress recombination and/or design of recombination-deficient vaccine strains. A second goal of this application is to create fundamental knowledge on the mechanism of RNA virus recombination using the PV model. During the next funding period, our central objectives will be: (1) Identify active-site determinants of RdRp incorporation fidelity that can be targeted for viral attenuation; (2) Exploit the promiscuity of the RdRp nascent base pair-binding pocket for antiviral therapy; (3) Elucidate a mechanism for template switching/strand transfer by PV RdRp and establish its relevance to RNA recombination by PV in cells. The proposed studies will create important knowledge that should contribute to development of strategies to treat and to prevent RNA viral infections, including those of current concern: Ebola virus, enterovirus D68, and Middle Eastern respiratory syndrome coronavirus.",
                "keywords": [],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "6398",
            "attributes": {
                "award_id": "5UG4LM012341-05",
                "title": "Regional Medical Library for the National Network of Libraries of Medicine Region 7 (Arizona, California, Hawaii, Nevada, and U.S. Territories in the Pacific Basin).",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Library of Medicine (NLM)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 21523,
                        "first_name": "LYNDA R",
                        "last_name": "HARDY",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2016-05-01",
                "end_date": "2021-10-31",
                "award_amount": 1446990,
                "principal_investigator": {
                    "id": 21524,
                    "first_name": "JUDITH C.",
                    "last_name": "CONSALES",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 818,
                            "ror": "",
                            "name": "UNIVERSITY OF CALIFORNIA LOS ANGELES",
                            "address": "",
                            "city": "",
                            "state": "CA",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 818,
                    "ror": "",
                    "name": "UNIVERSITY OF CALIFORNIA LOS ANGELES",
                    "address": "",
                    "city": "",
                    "state": "CA",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant): The NN/LM Pacific Southwest Region consists of a vast and diverse area of roughly 48 million people. The RML, based at the UCLA Louise M. Darling Biomedical Library in Los Angeles, supports a variety of libraries and health information centers in Arizona, California, Hawaii, Nevada, and the U. S. Territories in the Pacific. The Region stretches across six time zones, as well as the International Date Line. The geographic diversity presents a study in contrasts and great differences in information needs, from the urban hubs of Los Angeles, San Francisco, San Diego, Phoenix, and Las Vegas, to the remote island communities of the Pacific. The Region covers 11% of the total U.S. land area, and includes nearly 16% of the total U. S. population.         In addition to the great geographical distances, the Region is culturally, ethnically, and linguistically very diverse. Over 200 languages and dialects are known to be spoken and read in California, making it one of the most linguistically diverse areas in the world. Arizona is home to many Native Americans and Hispanic Americans, Nevada has many frontier counties, and Hawaii has the largest population of Native Hawaiians. Another challenge is the changing landscape of health sciences libraries, particularly hospital libraries, which are undergoing a continuing trend of downsizing and closure, primarily due to institutional economic pressures and retirements of senior librarians.         Despite these challenges, we have developed a program to publicize and promote the resources and services of the National Library of Medicine to as many audiences as possible. One of our key strategies is carefully planning the timing of webinars and other online meetings for the convenience of all parts of the Region. We also make extensive use of social media channels, two blogs, and an electronic announcement list to promote the word about new or revised NLM resources, upcoming events, technology tips, training information, and funding opportunities that may be of interest to our constituents. To support hospital librarians, we have extensively supported advocacy efforts by sponsoring workshops and providing professional development funding directed at hospital librarians wishing to enhance their skills.         The Louise M. Darling Biomedical Library proposes to continue providing Regional Medical Library services to the states of Arizona, California, Hawaii, Nevada, and U.S. Territories in the Pacific Basin for the 2016-2021 Cooperative Agreement. We recognize that technologies and health information priorities will change during the course of the agreement, and we stand ready to monitor and evaluate the communication tools used by our primary audiences, and to adapt our methods accordingly. We believe that the program put forward in this proposal to serve the NN/LM Pacific Southwest Region provides a balanced, logical, and flexible approach to improving access to health information and to promoting the systems and services of the National Library of Medicine.",
                "keywords": [
                    "Access to Information",
                    "Advocacy",
                    "Agreement",
                    "Area",
                    "Arizona",
                    "California",
                    "Communication Tools",
                    "Communities",
                    "Development",
                    "Economics",
                    "Education",
                    "Educational workshop",
                    "Event",
                    "Funding",
                    "Funding Opportunities",
                    "Geographic Factor",
                    "Geography",
                    "Hawaii",
                    "Health",
                    "Health Professional",
                    "Health Science Library",
                    "Hispanic Americans",
                    "Home environment",
                    "Hospital Libraries",
                    "Hospitals",
                    "Improve Access",
                    "Individual",
                    "Information Centers",
                    "Information Resources",
                    "International",
                    "Island",
                    "Language",
                    "Librarians",
                    "Libraries",
                    "Library Services",
                    "Linguistics",
                    "Los Angeles",
                    "Medical Libraries",
                    "Medicine",
                    "Methods",
                    "Mission",
                    "Monitor",
                    "Native Americans",
                    "Native Hawaiian",
                    "Nevada",
                    "Population",
                    "Public Health",
                    "Resources",
                    "Retirement",
                    "San Francisco",
                    "Services",
                    "Stretching",
                    "System",
                    "Technology",
                    "Time",
                    "Training",
                    "U-Series Cooperative Agreements",
                    "United States National Library of Medicine",
                    "Work",
                    "base",
                    "expectation",
                    "flexibility",
                    "frontier counties",
                    "improved",
                    "interest",
                    "meetings",
                    "member",
                    "outreach",
                    "pressure",
                    "programs",
                    "response",
                    "skills",
                    "social media",
                    "trend",
                    "webinar"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "6390",
            "attributes": {
                "award_id": "3U45ES019350-10S1",
                "title": "Project SEAMIST (South East Area Marine Industry Safety Training)",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute of Environmental Health Sciences (NIEHS)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 21505,
                        "first_name": "James W",
                        "last_name": "Remington",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2010-08-17",
                "end_date": "2021-05-31",
                "award_amount": 172977,
                "principal_investigator": {
                    "id": 21506,
                    "first_name": "Darren",
                    "last_name": "Cohen",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 934,
                            "ror": "https://ror.org/042bbge36",
                            "name": "Nova Southeastern University",
                            "address": "",
                            "city": "",
                            "state": "FL",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 934,
                    "ror": "https://ror.org/042bbge36",
                    "name": "Nova Southeastern University",
                    "address": "",
                    "city": "",
                    "state": "FL",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant): The Institute for Disaster and Emergency Preparedness at Nova Southeastern University proposes to continue and expand it's successful maritime workers hazardous materials handling training program, Project SEAMIST (South East Area Maritime Industry Safety Training) under the auspices of RFA-ES-14-008 \"Hazardous Materials Worker Health and Safety Training\". We also propose to extend our training model to workers who will respond to such incidents and will be responsible for cleaning up hazardous materials in the wake of such incidents with a concurrent program in Hazardous Material Maritime Industry Response Training Safety Initiative (HazMIRTSI). We have an established network of maritime industry clientele (companies and ports), safety training partners and law enforcement representatives in Virginia, Florida and Louisiana that we propose to expand into further Gulf (Mississippi and Texas; Project SEAMIST) and Atlantic (6 northern states; HazMIRTSI) states. These required training courses prepare maritime workers for the possibility of exposure to hazardous materials in the course of their regular duties, during accidents, and incidents due to either natural disasters or the possibility of targeted terrorism attacks. We provide three levels of training, from basic worker awareness to training trainers in order to reach the greatest number of at-risk personnel. Through HazMIRTSI, we will provide additional training on hazardous material disaster response preparedness.",
                "keywords": [
                    "Accidents",
                    "Area",
                    "Awareness",
                    "Cessation of life",
                    "Communities",
                    "Disasters",
                    "Docking",
                    "Educational Curriculum",
                    "Educational Status",
                    "Emergency Medical Technicians",
                    "Emergency Situation",
                    "Employee",
                    "Ensure",
                    "Event",
                    "Exposure to",
                    "Familiarity",
                    "Fire - disasters",
                    "Florida",
                    "Geography",
                    "Goals",
                    "Hazardous Substances",
                    "Health",
                    "Human Resources",
                    "Industry",
                    "Injury",
                    "Institutes",
                    "Law Enforcement",
                    "Louisiana",
                    "Methods",
                    "Mississippi",
                    "Modeling",
                    "Natural Disasters",
                    "Occupational",
                    "Occupations",
                    "Oceans",
                    "Personnel Management",
                    "Police",
                    "Population",
                    "Population Heterogeneity",
                    "Readiness",
                    "Risk",
                    "Rivers",
                    "Safety",
                    "Ships",
                    "Site",
                    "Terrorism",
                    "Texas",
                    "Time",
                    "Trainers Training",
                    "Training",
                    "Training Programs",
                    "Universities",
                    "Virginia",
                    "Work",
                    "ethnic diversity",
                    "first responder",
                    "hazardous materials disaster",
                    "hazardous materials worker",
                    "prevent",
                    "programs",
                    "public health relevance",
                    "response"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "6600",
            "attributes": {
                "award_id": "3R00AA024215-05S1",
                "title": "The role of serotonin signaling in the nucleus accumbens in excessive alcohol drinking",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute on Alcohol Abuse and Alcoholism (NIAAA)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 22119,
                        "first_name": "Qi-Ying",
                        "last_name": "Liu",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2017-06-01",
                "end_date": "2023-05-31",
                "award_amount": 154500,
                "principal_investigator": {
                    "id": 22120,
                    "first_name": "Catherine Anne",
                    "last_name": "Marcinkiewcz",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": []
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 220,
                    "ror": "https://ror.org/036jqmy94",
                    "name": "University of Iowa",
                    "address": "",
                    "city": "",
                    "state": "IA",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant): Alcohol abuse is a significant public health burden that is often difficult to manage with current treatment options. Chronic intermittent ethanol (CIE can induce adaptations in neural circuits that govern anxiety and motivated behavior and may have relevance for ethanol dependence. The goal of this application is to dissect neural circuits that are critically involved in dependence induced escalations in ethanol drinking. Recent evidence indicates that both 5-HT2CR and kappa opioid receptor (KOR) in the nucleus accumbens (NAc) shell contribute to CIE enhanced drinking. My central hypothesis is that chronic intermittent ethanol (CIE) augments 5-HT release in the NAc, which activate local dynorphin neurons that in turn reduce dopamine release. This degrades the reward value of ethanol and leads to increased ethanol consumption. In Specific Aim 1, I will use a multiplexed DREADD strategy to delineate the role of 5HT inputs to the NAc shell in CIE induced elevations in voluntary ethanol drinking. In Specific Aim 2, I will examine the impact of CIE on excitability f dynorphin neurons using slice electrophysiology. Based on preliminary data that stimulation of NAc dynorphin neurons modulates dopamine release in the NAc, I will also use slice voltammetry to examine how CIE shapes dynorphin-dopamine interactions in the NAc. Specific Aim 3 is designed to clarify the role of these NAc dynorphin neurons in excessive ethanol drinking after CIE. In total, the proposed research will provide essential information concerning the actions of CIE on the 5-HT-dynorphin circuits in the NAc that specifically drive excessive alcohol consumption.",
                "keywords": [
                    "Air",
                    "Alcohol abuse",
                    "Alcohol consumption",
                    "Alcohol dependence",
                    "Alcohol withdrawal syndrome",
                    "Alcoholism",
                    "Alcohols",
                    "Anxiety",
                    "Automobile Driving",
                    "Bathing",
                    "Behavior",
                    "Chronic",
                    "Coupled",
                    "Data",
                    "Dependence",
                    "Dopamine",
                    "Dynorphins",
                    "Electrophysiology (science)",
                    "Ethanol",
                    "Ethanol dependence",
                    "Exposure to",
                    "Frequencies",
                    "Goals",
                    "Heavy Drinking",
                    "Hyperactivity",
                    "Infusion procedures",
                    "Investigation",
                    "Left",
                    "Membrane",
                    "Messenger RNA",
                    "Microdialysis",
                    "Mus",
                    "Neurons",
                    "Nucleus Accumbens",
                    "Opioid Antagonist",
                    "Opioid agonist",
                    "Outcome",
                    "Pathogenesis",
                    "Pharmacology Study",
                    "Population",
                    "Proteins",
                    "Public Health",
                    "Receptor Signaling",
                    "Reporter",
                    "Reporting",
                    "Research",
                    "Rewards",
                    "Role",
                    "Serotonin",
                    "Shapes",
                    "Signal Transduction",
                    "Slice",
                    "Techniques",
                    "Testing",
                    "Tracer",
                    "Training",
                    "Up-Regulation",
                    "alcohol abuse therapy",
                    "alcohol exposure",
                    "alcohol seeking behavior",
                    "alcohol use disorder",
                    "base",
                    "career",
                    "design",
                    "designer receptors exclusively activated by designer drugs",
                    "drinking",
                    "drinking behavior",
                    "experimental study",
                    "gamma-Aminobutyric Acid",
                    "kappa opioid receptors",
                    "motivated behavior",
                    "neural circuit",
                    "neuroadaptation",
                    "optogenetics",
                    "public health relevance",
                    "response"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "7422",
            "attributes": {
                "award_id": "3U45ES006179-28S1",
                "title": "Hazardous Materials Worker Health and Safety Training (U45) Cooperative Agreement",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute of Environmental Health Sciences (NIEHS)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 7656,
                        "first_name": "Sharon",
                        "last_name": "Beard",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "1992-09-16",
                "end_date": "2020-07-31",
                "award_amount": 85914,
                "principal_investigator": {
                    "id": 20651,
                    "first_name": "Mitchel A",
                    "last_name": "Rosen",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 1418,
                            "ror": "",
                            "name": "RBHS-SCHOOL OF PUBLIC HEALTH",
                            "address": "",
                            "city": "",
                            "state": "NJ",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 1418,
                    "ror": "",
                    "name": "RBHS-SCHOOL OF PUBLIC HEALTH",
                    "address": "",
                    "city": "",
                    "state": "NJ",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "    DESCRIPTION (provided by applicant):  The NJ/NY Hazardous Materials Worker Training Center has a long history of effective training that meets the requirements of OSHA 29CFR1910.120, providing hazardous materials knowledge and skills to over 450,000 workers since 1987. Our Center will train workers about safety issues during clean-up hazardous waste sites, issues related to generation, treatment and storage of hazardous materials, and emergency response. The courses develop competency in workers to critically analyze dangerous situations, and enable them to identify safe work practices. Key principals of adult education are incorporated into our training, and training courses are developed to include peer-learning, hands-on activities, and development critical thinking skills. The Center has a robust evaluation plan, and will continue to expand the types of date collected on impact of training on workplace practice, as well as how training can more effectively influence workplace safety culture. The Center is applying for funding for the HWWT, ECWT, and HDPT programs. The focus of the HWWT program is to provide comprehensive training for workers who clean-up hazardous waste sites, are involved in the generation, treatment and storage of hazardous materials, and respond to transportation and other emergencies. Over the next five years, the Center proposes to train 51,890 workers in 2,315 courses in the HWWTP. The ECWTP will utilize focused strategies to recruit, train and employ underserved residents living in disadvantaged communities for construction and environmental remediation work. The Center has long-term, effective partnerships in minority and underserved communities that help reinforce occupational health and worker education, and mitigate health disparities at the community level. Our Center includes training in environmental justice, health and safety, and life skills, preparing trainees for a career in the environmental industry. Over the next five year, the Center proposes to train 300 workers in 75 courses in the ECWTP. The HDPT program enhances the safety and health of current hazardous materials workers and chemical responders by delivering training to workers responding to disaster. These courses focus on prevention and preparedness so that disaster response personnel are aware of safety and health hazards and mitigation techniques before they initiate a disaster response. Over the next five years, the Center proposes to train 14,191 workers in 740 courses in the HDPTP.",
                "keywords": [
                    "Address",
                    "Adult",
                    "Awareness",
                    "Buffaloes",
                    "Caring",
                    "Chemicals",
                    "Communities",
                    "Competence",
                    "Critical Thinking",
                    "Dangerousness",
                    "Development",
                    "Disadvantaged",
                    "Disasters",
                    "Disease",
                    "Ebola",
                    "Education",
                    "Educational Curriculum",
                    "Emergency Situation",
                    "Emergency response",
                    "Evaluation",
                    "Funding",
                    "Generations",
                    "Hazardous Substances",
                    "Hazardous Waste",
                    "Hazardous Waste Operations and Emergency Response",
                    "Hazardous Waste Sites",
                    "Health",
                    "Health Hazards",
                    "Health Personnel",
                    "Human Resources",
                    "Individual",
                    "Industry",
                    "Injury",
                    "Knowledge",
                    "Language",
                    "Life",
                    "Minority",
                    "Morbidity - disease rate",
                    "Municipalities",
                    "New Jersey",
                    "New York",
                    "Occupational Health",
                    "Occupational Safety",
                    "Police",
                    "Population",
                    "Prevention",
                    "Program Description",
                    "Property",
                    "Public Health",
                    "Public Health Schools",
                    "Puerto Rico",
                    "Readiness",
                    "Recording of previous events",
                    "Risk",
                    "Safety",
                    "Security",
                    "Site",
                    "Source",
                    "Target Populations",
                    "Techniques",
                    "Training",
                    "Transportation",
                    "U-Series Cooperative Agreements",
                    "United States",
                    "Universities",
                    "Work",
                    "Workplace",
                    "career",
                    "chemical responder",
                    "climate change",
                    "climate impact",
                    "college",
                    "disability",
                    "emergency service responder",
                    "environmental justice",
                    "first responder",
                    "hazard",
                    "hazardous materials disaster",
                    "hazardous materials worker",
                    "health disparity",
                    "improved",
                    "member",
                    "mortality",
                    "operation",
                    "peer learning",
                    "prevent",
                    "programs",
                    "public health relevance",
                    "recruit",
                    "remediation",
                    "resilience",
                    "response",
                    "skills",
                    "technical college",
                    "volunteer"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "9693",
            "attributes": {
                "award_id": "1T15LM013979-01",
                "title": "Johns Hopkins Training Program in Biomedical Informatics and Data Science",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Library of Medicine (NLM)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 21523,
                        "first_name": "LYNDA R",
                        "last_name": "HARDY",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2022-07-01",
                "end_date": "2027-06-30",
                "award_amount": 325816,
                "principal_investigator": {
                    "id": 10399,
                    "first_name": "CHRISTOPHER G",
                    "last_name": "CHUTE",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 765,
                            "ror": "https://ror.org/009avj582",
                            "name": "Oregon Health & Science University",
                            "address": "",
                            "city": "",
                            "state": "OR",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [
                    {
                        "id": 25518,
                        "first_name": "Hadi",
                        "last_name": "Kharrazi",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "awardee_organization": {
                    "id": 344,
                    "ror": "https://ror.org/00za53h95",
                    "name": "Johns Hopkins University",
                    "address": "",
                    "city": "",
                    "state": "MD",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": " PROJECT SUMMARY  Johns Hopkins University has recently re-established a multi-disciplinary, multi-school education program in Biomedical Informatics and Data Science (BIDS). The program is centrally coordinated and managed by the newly established Section of Biomedical Informatics and Data Science (BIDS) in the Division of General Internal Medicine. Faculty are drawn from the Johns Hopkins School of Medicine, the Bloomberg School of Public Health, the Whiting School of Engineering, the School of Nursing, and the Krieger School of Arts and Sciences. The program is structured around four tracks: Translational Bioinformatics, Clinical Research Informatics, Healthcare/Clinical Informatics, and Public Health Informatics. The program is built on the decades of informatics training tradition fostered by the Welch Medical Library and the Division of Health Sciences Informatics, now consolidated in the new BIDS Section. The new organization has established tight integration with the University and School of Medicine Education leadership, support systems, and infrastructure. We have revamped and extended our core curriculum to balance traditional informatics topics with current data science principles and methods. Specialized curricula have been developed in depth for each academic track of the program. Because of our newly formalized administrative structure, students are now free to take elective courses anywhere in the University with tuition reciprocity. Students also have access to the deep bench of research programs across informatics, computer science, biomedical engineering, and data science throughout the university, anchored by an ever-growing portfolio of BIDS grants and cooperative agreements in the BIDS Section such as the National COVID Cohort Collaborative (N3C). Thus, BIDS students have unprecedented opportunities for applied practica at depth to enrich and reinforce their education, provide a basis for theses, and more importantly achieve experience as collaborators, contributors, and authors. The University and School of Medicine provide state-of-the-art clinical and basic science data-analytics environments, including our Secure Analytic Framework Environment (SAFE) virtual machines, the Precision Medicine Analytics Platform (PMAP), the state HIE population-based EHR analyses platform (on PMAP), and well-curated clinical data warehouses in OMOP, PCORNet, ACT, and TriNetX formats. Training in biomedical ethics and the responsible conduct of research is deeply embedded in all practica involving patient data. Students have opportunity to work with well-established, well-funded research mentors, and to receive instruction from faculty with a deep commitment to education and training. The strengthening of translational science, multidisciplinary teams, and enterprise-class infrastructure and computer support across Johns Hopkins University provides students with opportunities to witness and participate in the new shape of collaborative science into the future.",
                "keywords": [
                    "Arts",
                    "Basic Science",
                    "Bioethics",
                    "Bioinformatics",
                    "Biomedical Engineering",
                    "Clinical Informatics",
                    "Clinical Research",
                    "Clinical Sciences",
                    "Computers",
                    "Data",
                    "Data Analytics",
                    "Data Science",
                    "Education",
                    "Educational Curriculum",
                    "Engineering",
                    "Environment",
                    "Equilibrium",
                    "Faculty",
                    "Fostering",
                    "Funding",
                    "Future",
                    "Grant",
                    "Health Sciences",
                    "Healthcare",
                    "Informatics",
                    "Infrastructure",
                    "Instruction",
                    "Internal Medicine",
                    "Leadership",
                    "Medical Libraries",
                    "Mentors",
                    "Methods",
                    "Patients",
                    "Public Health Informatics",
                    "Public Health Schools",
                    "Research",
                    "School Nursing",
                    "Schools",
                    "Science",
                    "Secure",
                    "Shapes",
                    "Structure",
                    "Students",
                    "Support System",
                    "Training",
                    "Training Programs",
                    "Training and Education",
                    "Translational Research",
                    "U-Series Cooperative Agreements",
                    "Universities",
                    "Work",
                    "biomedical informatics",
                    "clinical data warehouse",
                    "cohort",
                    "computer science",
                    "coronavirus disease",
                    "experience",
                    "informatics training",
                    "medical schools",
                    "multidisciplinary",
                    "population based",
                    "precision medicine",
                    "programs",
                    "responsible research conduct",
                    "virtual environment",
                    "virtual machine"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "15443",
            "attributes": {
                "award_id": "5R01DA059415-02",
                "title": "Integrating eye-tracking and ECG methodologies for remote infant neurocognitive assessments in the home",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute on Drug Abuse (NIDA)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 12931,
                        "first_name": "Janani",
                        "last_name": "Prabhakar",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2023-09-30",
                "end_date": "2027-07-31",
                "award_amount": 540717,
                "principal_investigator": {
                    "id": 22463,
                    "first_name": "Natalie Hiromi",
                    "last_name": "Brito",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": [
                        {
                            "id": 167,
                            "ror": "https://ror.org/0190ak572",
                            "name": "New York University",
                            "address": "",
                            "city": "",
                            "state": "NY",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 167,
                    "ror": "https://ror.org/0190ak572",
                    "name": "New York University",
                    "address": "",
                    "city": "",
                    "state": "NY",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "“This study is part of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative bolsters research across NIH to improve treatment for opioid misuse and addiction.” Use of remote data collection methodology in developmental research has increased significantly, in part due to in-person data collection stoppage that occurred at the start of the COVID-19 pandemic. These kinds of data collection methods are likely to decrease barriers to participation for families, increase sample sociodemographic diversity, and could potentially address common problems in the field related to statistical power and sampling bias, all significant issues associated with construct and ecological validity. The central objective of this proposal is to support the rigorous application and validation of remote infant testing methodology of early cognitive development when infants are 4, 8, and 12-month of age. We will recruit 300 families who are traditionally underrepresented in developmental neuroscience research to participate in this longitudinal study. The primary aims of this project are to (i) establish and validate remote physiological and behavioral measurements of infant attention and memory skills, (ii) investigate the impact of caregiver-infant physiological co-regulation on infant outcomes, and (iii) evaluate predictors of infant attention phenotypes and longitudinal associations with socioemotional outcomes and autism risk. This proposal integrates multi-level data to improve measurement of infant cognition within the home and will substantially enrich our understanding of developmental trajectories and mechanisms across socio-demographically diverse environments and contexts, leading to increased precision for prevention and intervention efforts.",
                "keywords": [],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "14657",
            "attributes": {
                "award_id": "1R13AI183910-01",
                "title": "Virus Structure and Assembly",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute of Allergy and Infectious Diseases (NIAID)"
                ],
                "program_reference_codes": [],
                "program_officials": [
                    {
                        "id": 22396,
                        "first_name": "Martin",
                        "last_name": "Gutierrez",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
                        "websites": null,
                        "desired_collaboration": null,
                        "comments": null,
                        "affiliations": []
                    }
                ],
                "start_date": "2024-04-18",
                "end_date": "2024-09-30",
                "award_amount": 35000,
                "principal_investigator": {
                    "id": 31350,
                    "first_name": "Gino",
                    "last_name": "Cingolani",
                    "orcid": null,
                    "emails": "",
                    "private_emails": "",
                    "keywords": null,
                    "approved": true,
                    "websites": null,
                    "desired_collaboration": null,
                    "comments": null,
                    "affiliations": []
                },
                "other_investigators": [],
                "awardee_organization": {
                    "id": 1511,
                    "ror": "",
                    "name": "FEDERATION OF AMER SOC FOR EXPER BIOLOGY",
                    "address": "",
                    "city": "",
                    "state": "MD",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "“The Virus Structure and Assembly Conference” is the premier international meeting for structural virology, attracting hundreds of researchers at every career level from around the world. Organized as part of the FASEB Science Research Conference series, it has been running biennially since 1990. The Conference covers a broad range of bacterial and eukaryotic viruses, with an initial focus on virus structure and assembly pathways, mechanisms of virus entry, virus-host interactions, and viral replication, recently expanded to encompass viral genomics and evolution, therapeutics, vaccines, and nanotechnological applications. A unique feature of the Virus Structure and Assembly Conference has been the ability to merge and integrate tremendous advances in biophysical studies of viruses with functional aspects of virus biology. Fueled by the cryo-electron microscopy revolution, the FASEB meeting has brought together structural biologists, virologists, and microbiologists, promoting interactions and guiding young researchers to embrace studies on viruses. The broad focus on virus systems studied from different angles encourages inter-disciplinary approaches, stimulates collaborations, and supports the rapid transfer of technology, overcoming silos and roadblocks of more topic-focused conferences. To maintain its legacy of scientific innovation in virology, our program includes top investigators in all areas of structural virology from around the world, more than one-third of whom are new to the Conference. For 2024, we will strengthen the focus on pandemic readiness with ample exposure to RNA viruses such as HIV-1, Influenza, and SARS-CoV-2.  A vital aspect of the FASEB Virus Structure and Assembly Conference pedigree is the focus on mentoring and training sessions that we achieve through extensive small-group activities between senior and junior researchers. Scientific discussions with speakers and among participants are vital to encourage the flow of new ideas and new collaborations, expanding the base and bringing new scientists to the Conference. In 2024, we will have feature daily “Meet the Expert” sessions as well as “Meet the Sponsor” and “Flash Talk” sessions for graduate students to present posters selected by our judges for 15-minute platform talks. A rich “Career Development Workshop” will be offered to early-stage researchers with guests from academia, the private sector, and government agencies, who will present, compare and contrast alternative career paths in science. All sessions will keep a strong focus on women and underrepresented groups in science, creating awareness and promoting scientific inclusiveness. Robust fundraising primarily made possible by our super-sponsor Thermo Scientific and support through this NIH R13 will allow us to offer travel scholarships to an unprecedented number of graduate students, postdocs, and early-stage researchers. While continuing the tradition of top-quality FASEB meetings, the 2024 Virus Structure and Assembly Conference will also substantially attempt to enlarge the scientific base and promote the participation of underrepresented scientists.",
                "keywords": [
                    "2019-nCoV",
                    "Academia",
                    "Active Learning",
                    "Anti-viral Response",
                    "Archaeal Viruses",
                    "Area",
                    "Award",
                    "Awareness",
                    "Bacteriophages",
                    "Biological",
                    "Biology",
                    "Biomedical Technology",
                    "Career Choice",
                    "Cells",
                    "Collaborations",
                    "Communication",
                    "Complement",
                    "Cryoelectron Microscopy",
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                    "Dedications",
                    "Defense Mechanisms",
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                    "Doctor of Philosophy",
                    "Educational process of instructing",
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                    "Pathway interactions",
                    "Postdoctoral Fellow",
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                    "RNA Viruses",
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                    "Scientist",
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                    "Structural Biologist",
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                    "Students",
                    "System",
                    "Technology Transfer",
                    "Textbooks",
                    "Therapeutic",
                    "Training",
                    "Travel",
                    "Underrepresented Minority",
                    "Underrepresented Populations",
                    "United States National Institutes of Health",
                    "Vaccines",
                    "Viral",
                    "Virus",
                    "Virus Assembly",
                    "Virus Replication",
                    "Woman",
                    "Women&apos",
                    "s Group",
                    "base",
                    "biophysical analysis",
                    "career",
                    "career development",
                    "comparative",
                    "design",
                    "genetic pedigree",
                    "graduate student",
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                    "macromolecule",
                    "meetings",
                    "pandemic preparedness",
                    "pathogenic virus",
                    "posters",
                    "programs",
                    "success",
                    "symposium",
                    "tool",
                    "viral genomics",
                    "virology",
                    "virus classification",
                    "virus host interaction",
                    "virus infection mechanism"
                ],
                "approved": true
            }
        }
    ],
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            "page": 1,
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        }
    }
}