Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=5&sort=title
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=title", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1442&sort=title", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=6&sort=title", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=4&sort=title" }, "data": [ { "type": "Grant", "id": "7571", "attributes": { "award_id": "3R34DA050266-01S2", "title": "2/2 Optimizing access, engagement and assessment to elucidate prenatal influences on neurodevelopment: The Brains Begin Before Birth(B4 ) Midwest Consortium", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Drug Abuse (NIDA)" ], "program_reference_codes": [], "program_officials": [ { "id": 12931, "first_name": "Janani", "last_name": "Prabhakar", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2019-09-30", "end_date": "2022-03-31", "award_amount": 158585, "principal_investigator": { "id": 23108, "first_name": "LAUREN S", "last_name": "WAKSCHLAG", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 924, "ror": "", "name": "NORTHWESTERN UNIVERSITY AT CHICAGO", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 924, "ror": "", "name": "NORTHWESTERN UNIVERSITY AT CHICAGO", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true }, "abstract": "PROJECT SUMMARY: The accelerating U.S. opioid crisis requires urgent scientific and public health action. Maternal perinatal use/abuse is particularly deleterious due to its reverberating intergenerational impact. Though prenatal exposure to opioids and other substances have adverse effects on neurodevelopment, advances in neuroimaging and developmentally- sensitive phenotypic measurement now enable characterization of typical and atypical brain- behavior pathways on an unprecedented scale. Mechanistic study that traces the multi-level determinants and patterns of risk and resilience from the prenatal period through childhood requires a large, national cohort that accounts for regional and racial/ethnic variation. We propose the Brains Begin Before Birth (B4) Midwest Consortium, a partnership of neuroscience, substance use, perinatal mental health and child welfare scientists at Washington University School of Medicine (WUSM) and neuroscience, bioethics, pediatric population health, maternal- fetal and addiction scientists at Northwestern University (NU). Along with scientific complementarity, a strength of this regional Consortium is its ability to leverage the contrasting approaches of Illinois (punitive) and Missouri (non-punitive) to prenatal opioid use, providing an exceptional platform for examining the impact of jurisdictional variations on science and practice. Together we provide a framework for addressing three major areas of challenge key to a high-quality, representative, national multi-site study: (1) Legal/Ethical: Led by NU bioethics and population health experts, we propose a mixed methods approach to delineating barriers and generating solutions to scientific engagement of opioid using pregnant women from varied jurisdictions; (2) Recruitment/Retention: Led by NU experts in behavioral economics approaches to research participation and WUSM experts in care coordination, child welfare and mobile technology, we use innovative methods to test differential effectiveness of messaging in recruitment materials using eye tracking, and employ novel apps and care coordination methods for retention enhancement; and (3) Imaging/Assessment Methods: Led by neuroscience and substance use experts at WUSM and an NU data scientist, we generate best practices recommendations for an informed protocol via: (i) pilot testing a comprehensive pre-/perinatal maternal substance/mental health protocol; (ii) obtaining feasibility data on MRI scans in neonatal abstinence syndrome, also testing other developmental imaging modalities (e.g., EEG, fNIRS), including in community settings; and (iii) applying state-of-the-art epidemiologic risk prediction methods to extant Consortium data to identify methods and timing of key assessments that provide added predictive value. All activities draw on extensive community stakeholder partnerships. Our central focus is the prenatal-early childhood period, with a framework designed to enable meaningful contributions to consortia including later childhood. Transdisciplinary integration spanning population health to neuroscience is essential to ensure that a large national effort delineating the impact of this pernicious epidemic and corollary risk on health and development of children and families can be fully realized.", "keywords": [ "Accounting", "Address", "Adverse effects", "Age", "Alcohol or Other Drugs use", "Area", "Behavior assessment", "Behavioral", "Bioethics", "Bioethics Consultants", "Biological Assay", "Birth", "Brain", "Catalogs", "Categories", "Child", "Child Development", "Child Welfare", "Childhood", "Clinical", "Cognitive", "Collaborations", "Communities", "Data", "Data Scientist", "Data Set", "Development", "Discipline", "Effectiveness", "Electroencephalography", "Emotional", "Ensure", "Epidemic", "Epidemiology", "Equilibrium", "Ethics", "Exposure to", "Family", "Feedback", "Fertilization", "Follow-Up Studies", "Fostering", "Functional Magnetic Resonance Imaging", "Goals", "Health", "Human", "Illinois", "Image", "Individual Differences", "Infant", "Institution", "Interview", "Leadership", "Legal", "Link", "Longitudinal Studies", "MRI Scans", "Manuscripts", "Measurement", "Mental Health", "Methodology", "Methods", "Midwestern United States", "Missouri", "Modality", "Modeling", "Modification", "Multimodal Imaging", "Neonatal Abstinence Syndrome", "Neurosciences", "Opioid", "Outcome", "Pathway interactions", "Pattern", "Perinatal", "Phase", "Phenotype", "Policies", "Population", "Postpartum Period", "Predictive Value", "Pregnant Women", "Protocols documentation", "Public Health", "Recommendation", "Reporting", "Reproducibility", "Research", "Research Design", "Research Personnel", "Risk", "Science", "Scientist", "Site", "Social Interaction", "Structure", "Surveys", "Testing", "Universities", "Variant", "Washington", "Woman", "addiction", "adverse outcome", "age group", "base", "behavioral economics", "brain behavior", "care coordination", "cohort", "community setting", "design", "drug of abuse", "early childhood", "early life exposure", "falls", "fetal", "high risk", "imaging modality", "infant morbidity/mortality", "innovation", "intergenerational", "longitudinal design", "medical schools", "middle childhood", "mobile application", "mobile computing", "multidisciplinary", "neurodevelopment", "neuroimaging", "novel", "offspring", "opioid abuse", "opioid epidemic", "opioid use", "opioid use in pregnancy", "peer", "perinatal mental health", "phase 2 designs", "population health", "portability", "postnatal", "prenatal", "prenatal exposure", "prenatal influence", "psychosocial", "racial and ethnic", "recruit", "regional difference", "relating to nervous system", "research study", "resilience", "retention rate", "risk prediction model" ], "approved": true } }, { "type": "Grant", "id": "6328", "attributes": { "award_id": "3U54CA143924-12S2", "title": "2/2 Partnership for Native American Cancer Prevention", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Cancer Institute (NCI)" ], "program_reference_codes": [], "program_officials": [ { "id": 21344, "first_name": "LEEANN ODETTE", "last_name": "Bailey", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2009-09-01", "end_date": "2024-08-31", "award_amount": 166201, "principal_investigator": { "id": 21345, "first_name": "MARGARET M", "last_name": "BRIEHL", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 438, "ror": "https://ror.org/03m2x1q45", "name": "University of Arizona", "address": "", "city": "", "state": "AZ", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 21346, "first_name": "Andrew S", "last_name": "Kraft", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 438, "ror": "https://ror.org/03m2x1q45", "name": "University of Arizona", "address": "", "city": "", "state": "AZ", "zip": "", "country": "United States", "approved": true }, "abstract": "The Navajo Nation is reporting the highest per-capita coronavirus infection rate in the United States (US) with 3.6% infected and a 4.7% case fatality rate, despite quickly responding to the first cases with prevention messaging and community lock-down measures. Chronic conditions like diabetes and obesity, prevalent on the Navajo Nation, have been associated with severe COVID-19 illness. Although several factors have contributed to the high incidence of infection in this population, cultural and economic factors are playing a major role. These conditions complicate maintaining medical care while engaging with the recommendations to reduce COVID-19 transmission. The impact of COVID-19 for the Navajo Nation can become broader than the immediate morbidity and mortality; cancer prevention and early detection screenings may have been postponed, cancer treatments may have been stopped or delayed. It is unknown how SARS-CoV-2 infection and the measures to prevent infection will impact health care delivery, including cancer screening, detection, and care. To address these disparities and to better respond to the impact of the pandemic within one of the most impoverished regions of the US, we propose to use a multimethod approach to determine the impact of the COVID-19 pandemic from the perspectives both the health care providers and facilities and from the individual patients’ perspective on health related care delivery, including cancer prevention, early detection, screening, diagnosis, and treatment planning, and the interaction of chronic diseases with SARS-CoV-2 infection. Specifically, we will 1) investigate provider/health care worker perceptions about COVID-19 impacts using online surveys and semi-structured interviews and 2) investigate changes in patients’ and communities’ care seeking capacity, using online and telephone surveys and Zoom-based focus groups with members of the community and with cancer patients. Our research team from two universities and Navajo community members is uniquely suited to respond because of our current partnerships with the Navajo Nation and medical facilities. Beyond understanding what factors are contributing to the high transmission on the Navajo Nation, the data collected for this project may allow for future assessment of the impact of delay in cancer treatment or detection for patients. Through surveys, semi-structured interviews, and focus groups, we will provide a broad assessment of the experiences of Navajo households and Navajo cancer patients throughout the pandemic and how this widespread community transmission and infection has influenced access, utilization, and quality of health care.", "keywords": [ "2019-nCoV", "Address", "American Indians", "Arizona", "COVID-19", "COVID-19 pandemic", "Cancer Center", "Cancer Detection", "Cancer Patient", "Caring", "Case Fatality Rates", "Chronic", "Chronic Disease", "Cities", "Communities", "Communities That Care", "Community Health", "Coronavirus Infections", "Data", "Detection", "Diabetes Mellitus", "Diagnosis", "Drug Prescriptions", "Early Diagnosis", "Economic Factors", "Faculty", "Family", "Focus Groups", "Future", "Generations", "Health", "Health Personnel", "Health Services Accessibility", "Health care facility", "Healthcare", "Home environment", "Hour", "Household", "Incidence", "Individual", "Infection", "Infection prevention", "Internet", "Interview", "Life", "Measures", "Medical", "Morbidity - disease rate", "Native Americans", "Navajo", "Obesity", "Oncology", "Patients", "Perception", "Play", "Population", "Prevention", "Prevention program", "Provider", "Recommendation", "Reporting", "Research", "Research Methodology", "Risk", "Role", "Screening for cancer", "Speed", "Structure", "Surveys", "Telemedicine", "Telephone", "Time", "Travel", "United States", "Universities", "Water", "Work", "base", "cancer care", "cancer prevention", "cancer therapy", "care delivery", "care providers", "care seeking", "cohort", "experience", "follow-up", "health care delivery", "health care quality", "individual patient", "infection rate", "member", "mortality", "pandemic disease", "prevent", "response", "screening", "transmission process", "treatment planning" ], "approved": true } }, { "type": "Grant", "id": "11396", "attributes": { "award_id": "1U24HL164284-01", "title": "2/2 REPRIEVE Extension for Trial Completion", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Heart Lung and Blood Institute (NHLBI)" ], "program_reference_codes": [], "program_officials": [ { "id": 10288, "first_name": "Patrice", "last_name": "Desvigne-Nickens", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-05-01", "end_date": "2026-04-30", "award_amount": 1243585, "principal_investigator": { "id": 27449, "first_name": "Michael Tse-Yin", "last_name": "Lu", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 27450, "first_name": "Heather Jane", "last_name": "Ribaudo", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 736, "ror": "https://ror.org/002pd6e78", "name": "Massachusetts General Hospital", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "This proposal will support the Data Coordinating Center (DCC) for the Randomized Trial to Prevent Vascular Events in HIV Trial (REPRIEVE) Extension for up to two additional years, with an additional year for study close-out. This additional time is necessary to collect the major adverse cardiovascular events (MACE) required to ensure adequate power to address the primary aim of REPRIEVE, to determine the efficacy of statins as a primary cardiovascular prevention strategy in HIV. Completion of the trial will protect the value of the initial NIH investment and leverage existing REPRIEVE infrastructure, with its data analytical and oversight structures. This DCC proposal is a companion to the REPRIEVE Clinical Coordinating Center (CCC) proposal. REPRIEVE is a multicenter, randomized, placebo controlled, pragmatic trial investigating the efficacy of statins for primary prevention of cardiovascular disease (CVD) events (primary endpoint) in 7,770 persons with HIV (PWH) without known CVD and with low to moderate CVD risk as per the 2013 ACC/AHA Pooled Cohort Equations, (referred to as ASCVD risk). To understand the biology of statin effects, 805 participants were co- enrolled in an embedded mechanistic substudy that will determine the effects of statins on non-calcified plaque volume and high risk plaque morphology using coronary computed tomographic angiography (CTA), as well as on blood biomarkers of vascular inflammation and immune activation after 4 months and two years. Further, in response to the global SARS-CoV-2 pandemic, REPRIEVE will address critical knowledge gaps regarding the epidemiology of SARS-CoV-2 infection and COVID-related CVD complications among PWH, and determine the protective statin effects for COVID disease across the globe. In the proposed extension, the REPRIEVE DCC will continue to provide methodological and logistical support for the collection, quality control, and analysis of data including rigorous, timely, and independent adjudication of potential MACE events. Furthermore, the DCC remains responsible for statistical design and analysis, assistance in protocol development, data management, CTA data acquisition and interpretation, biospecimen analysis, and electronic communications.", "keywords": [ "AIDS clinical trial group", "Address", "Ancillary Study", "Angiography", "Authorization documentation", "Biological Assay", "Biological Markers", "Biology", "Blood", "Blood Vessels", "COVID-19 pandemic", "Cardiovascular Diseases", "Cardiovascular system", "Clinical", "Clinical Data", "Clinical Trials", "Clinical Trials Data Monitoring Committees", "Collaborations", "Collection", "Companions", "Computers", "Coronary artery", "Data", "Data Analyses", "Data Analytics", "Data Collection", "Data Coordinating Center", "Data Reporting", "Disease", "Electronic Mail", "Enrollment", "Ensure", "Epidemiology", "Equation", "Event", "HIV", "Heart Diseases", "Information Dissemination", "Infrastructure", "Investments", "Knowledge", "Laboratories", "Lead", "Leadership", "Letters", "Methodology", "Morphology", "Myocardial Infarction", "National Heart Lung and Blood Institute", "Outcome", "Participant", "Persons", "Placebo Control", "Preparation", "Prevention strategy", "Primary Prevention", "Procedures", "Process", "Publications", "Quality Control", "Randomized", "Reporting", "Research", "Research Design", "Risk", "SARS-CoV-2 infection", "Site", "Statistical Data Interpretation", "Stroke", "Structure", "System", "Time", "Training", "United States National Institutes of Health", "X-Ray Computed Tomography", "adjudication", "archive data", "cardiovascular disorder prevention", "cardiovascular disorder risk", "cohort", "coronary computed tomography angiography", "coronavirus disease", "data acquisition", "data archive", "data exchange", "data management", "data repository", "data sharing", "design", "follow-up", "high risk", "imaging study", "immune activation", "inflammatory marker", "medical specialties", "meetings", "pragmatic trial", "prevent", "primary endpoint", "protocol development", "randomized trial", "response", "stroke event", "tool", "trial design", "vascular inflammation" ], "approved": true } }, { "type": "Grant", "id": "14733", "attributes": { "award_id": "1U24HL168491-01A1", "title": "2/2 Self-directed mobile adaptive coping skills intervention to improve psychological distress symptoms among cardiorespiratory failure survivors: the Blueprint RCT", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Heart Lung and Blood Institute (NHLBI)" ], "program_reference_codes": [], "program_officials": [ { "id": 22589, "first_name": "CHRISTIAN RENE", "last_name": "Gomez", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2024-02-15", "end_date": "2029-01-31", "award_amount": 555597, "principal_investigator": { "id": 21554, "first_name": "Catherine Lee", "last_name": "Hough", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 21697, "first_name": "Cynthia D", "last_name": "Morris", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 765, "ror": "https://ror.org/009avj582", "name": "Oregon Health & Science University", "address": "", "city": "", "state": "OR", "zip": "", "country": "United States", "approved": true }, "abstract": "Cardiorespiratory conditions such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are among the most common causes of mortality and morbidity. They are also notable for high rates of persistent psychological distress symptoms including depression, anxiety, and PTSD that worsen quality of life and outcomes of the underlying conditions. Yet there are few effective strategies able to overcome barriers of limited access to mental health care. Even less is known about distress management among people from structurally disadvantaged backgrounds such as racially and ethnically minoritized populations because of their suboptimal representation in relevant clinical trials. To fill this gap, we developed Blueprint, an adaptive coping skills training intervention, and have optimized it over years of research. We conducted a multicenter RCT (PCORI PFA 195) of a telephone- and web-based version among those recently hospitalized with serious cardiorespiratory conditions, finding that it reduced depression symptoms and improved quality of life among those with elevated baseline distress. Informed by lessons learned about intervention delivery and eligibility criteria, we next conducted a single-center pilot RCT (R34 HL145387) that targeted a broader population and tested a completely automated, self-guided, symptom-responsive mobile app version of Blueprint. We found excellent adherence and a strong effect on depression, anxiety, PTSD, and quality of life compared to control. Given these promising findings, a formal test of the Blueprint adaptive coping skills training intervention’s efficacy is needed. Therefore, we propose a 5-year multicenter RCT with 6-month follow up in which 400 cardiorespiratory failure survivors with elevated symptoms of psychological distress post-discharge are randomized to either Blueprint or an Education Program control, both delivered through similar mobile app platforms. Our specific aims will: (1) Test Blueprint vs. control on symptoms of depression, anxiety, PTSD, and quality of life; (2) Determine patient-level characteristics associated with a great treatment response among sociodemographic subgroups of interest, also applying a heterogeneity of treatment effects analysis to identify other groups of clinical relevance; and (3) Ensure off-the-shelf intervention readiness for implementation by using an exploratory mixed-methods hybrid type 1 implementation framework analysis that integrates semi-structured interviews with trial participants and quantitative trial data from Aims 1 and 2. This DCC proposal will provide the data management infrastructure and will maintain study integrity. Innovative elements include a fully automated mobile health delivery system that personalizes content in response to changes in symptom trajectories, a focus on racially and ethnically minoritized persons, the integration of a Spanish language intervention version, and strong community engagement. This project addresses national research priorities and could advance the field with a personalizable yet population- focused therapy that could be scaled broadly and efficiently to enhance mental health equity.", "keywords": [ "Acute Respiratory Distress Syndrome", "Address", "Adherence", "Age", "Anxiety", "Behavioral", "Biometry", "Black race", "COVID-19", "COVID-19 pneumonia", "Characteristics", "Clinical", "Clinical Trials", "Cognitive Therapy", "Colorado", "Congestive Heart Failure", "Coping Skills", "Critical Illness", "Data", "Data Reporting", "Disease", "Distress", "Education", "Educational Intervention", "Electronic Health Record", "Elements", "Eligibility Determination", "Enrollment", "Ensure", "Ethnic Origin", "Failure", "Gender", "Health", "Heterogeneity", "Hispanic", "Home", "Hospitalization", "Hospitals", "Hybrids", "Implementation readiness", "Infrastructure", "Intervention", "Interview", "Language", "Lead", "Learning", "Mental Depression", "Mental Health", "Mental Health Services", "Methods", "Modeling", "Morbidity - disease rate", "Online Systems", "Oregon", "Outcome", "Participant", "Patients", "Persons", "Population", "Population Heterogeneity", "Post-Traumatic Stress Disorders", "Problem Solving", "Protocols documentation", "Quality of life", "Race", "Randomized", "Reach Effectiveness Adoption Implementation and Maintenance", "Relaxation", "Reporting", "Research", "Research Priority", "Safety", "Sampling", "Security", "Self Direction", "Self Efficacy", "Sepsis", "Severity of illness", "Site", "Structure", "Subgroup", "Survivors", "Symptoms", "Telephone", "Testing", "Time", "Training Programs", "Treatment Efficacy", "Work", "clinically relevant", "community engagement", "comparison control", "data infrastructure", "data integrity", "data management", "data quality", "depressive symptoms", "design", "disadvantaged background", "efficacy testing", "emotion regulation", "ethnic minority population", "experience", "follow-up", "future implementation", "health care delivery", "health equity", "implementation framework", "implementation outcomes", "improved", "innovation", "interest", "intervention delivery", "mHealth", "mobile application", "mortality", "physical symptom", "primary outcome", "programs", "psychological distress", "psychological symptom", "quality assurance", "racial minority population", "recruit", "response", "skills", "social", "social factors", "sociodemographics", "symptom treatment", "therapy design", "tool", "treatment effect", "treatment response" ], "approved": true } }, { "type": "Grant", "id": "16087", "attributes": { "award_id": "1U24AT013110-01", "title": "2/2 Self-directed mobile mindfulness intervention to improve psychological distress symptoms among cardiorespiratory failure survivors: the Lift RCT", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Center for Complementary and Integrative Health (NCCIH)", "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 44565, "first_name": "LANAY MARIE", "last_name": "MUDD", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2026-07-15", "end_date": "2031-06-30", "award_amount": 619287, "principal_investigator": { "id": 21554, "first_name": "Catherine Lee", "last_name": "Hough", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 21697, "first_name": "Cynthia D", "last_name": "Morris", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 3496, "ror": "", "name": "OREGON HEALTH & SCIENCE UNIVERSITY", "address": "", "city": "", "state": "OR", "zip": "", "country": "United States", "approved": true }, "abstract": "Cardiorespiratory conditions such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are among the most common causes of mortality and morbidity. They are associated with high rates of persistent psychological distress symptoms including depression, anxiety, and PTSD that worsen quality of life and outcomes of the underlying conditions. Yet there are few effective strategies able to overcome barriers of limited access to mental health care. Even less is known about distress management among people from structurally disadvantaged backgrounds such as racially and ethnically minoritized populations. To address this gap, we developed Lift from the ground up with patient input; Lift is a completely automated and self-directed mindfulness training intervention. Lift reduced depression symptoms and improved quality of life compared to an education program control in a multicenter pilot RCT (R34 AT008819) among those recently hospitalized with serious cardiorespiratory conditions. Next, a 247-person multicenter 2x2x2 factorial optimization trial (U01 AT00974) compared 8 intervention versions differing by program introduction (app vs. therapist), dose (standard vs. high), and approach to in-the-moment symptom management (app vs. therapist). This trial demonstrated that while all versions had a strong effect on depression, anxiety, and PTSD symptoms, the high dose, app-only version was optimal for effect, adherence, and retention. Given these promising findings, we propose a formal test of the efficacy of an optimized Lift mobile mindfulness intervention in a 4-site multicenter RCT with 6-month follow up among 450 cardiorespiratory failure survivors with elevated post-discharge symptoms of psychological distress. Our specific aims will: (1) Test Lift vs. an education program control delivered by similar platforms on symptoms of depression, anxiety, PTSD, and quality of life; (2a) Determine patient-level characteristics associated with a greater treatment response among a priori-defined subgroups using a heterogeneity of treatment effects analysis; (2b) Explore novel adherence metrics and outcomes; and (3) Ensure off-the-shelf intervention readiness with an exploratory mixed-methods hybrid type 1 implementation framework analysis that integrates quantitative trial implementation data with semi-structured trial participant interviews. This DCC proposal creates the data management infrastructure for the Lift trial to maintain study integrity. Innovative elements include a fully automated mobile health delivery system that personalizes content in response to changes in symptom trajectories, a focus on racially and ethnically minoritized populations, the inclusion of interventions in Spanish language, and strong community engagement.", "keywords": [ "Acute Respiratory Distress Syndrome", "Address", "Adherence", "Affect", "Age", "Anxiety", "Behavioral", "Biometry", "COVID-19", "COVID-19 pneumonia", "Characteristics", "Clinical", "Clinical Trials", "Collaborations", "Congestive Heart Failure", "Data", "Data Reporting", "Demographic Factors", "Disease", "Distress", "Dose", "Education", "Educational Intervention", "Electronic Health Record", "Elements", "Enrollment", "Ensure", "Ethnic Origin", "Failure", "Financial Hardship", "Gender", "Goals", "Health", "Health Services Accessibility", "Heterogeneity", "Hospitalization", "Hybrids", "Infrastructure", "Intensive Care Units", "Intervention", "Language", "Lead", "Lifting", "Measures", "Mental Depression", "Mental Health", "Mental Health Services", "Methods", "Mindfulness Training", "Minority Groups", "Morbidity", "Mosses", "Multicenter Trials", "Outcome", "Participant", "Patients", "Persons", "Pneumonia", "Population", "Population Heterogeneity", "Post-Traumatic Stress Disorders", "Protocols documentation", "Quality of life", "Questionnaires", "Race", "Randomized", "Reach Effectiveness Adoption Implementation and Maintenance", "Readiness", "Recording of previous events", "Reporting", "Research", "Safety", "Sampling", "Security", "Self Direction", "Self Efficacy", "Sepsis", "Severity of illness", "Site", "Social support", "Socioeconomic Factors", "Socioeconomic Status", "Spanish", "Spanish/English", "Structure", "Subgroup", "Survivors", "Symptoms", "Testing", "Training", "Training Programs", "Trajectory", "Work", "clinical implementation", "clinical trial participant", "cohort", "community engagement", "comparison control", "data infrastructure", "data integrity", "data management", "data quality", "depressive symptoms", "design", "disadvantaged background", "effectiveness/implementation design", "efficacy testing", "emotion regulation", "ethnic minority population", "experience", "follow-up", "future implementation", "health care delivery", "implementation framework", "implementation intervention", "improved", "innovation", "mHealth", "mindfulness", "mindfulness intervention", "mindfulness-based stress reduction", "mobile application", "mortality", "multiphase optimization strategy", "novel", "participant interview", "physical symptom", "primary outcome", "programs", "psychological distress", "psychological symptom", "quality assurance", "quality of li" ], "approved": true } }, { "type": "Grant", "id": "12061", "attributes": { "award_id": "1U24HL166784-01A1", "title": "2/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Heart Lung and Blood Institute (NHLBI)" ], "program_reference_codes": [], "program_officials": [ { "id": 22589, "first_name": "CHRISTIAN RENE", "last_name": "Gomez", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-09-01", "end_date": "2030-08-31", "award_amount": 1175434, "principal_investigator": { "id": 27913, "first_name": "Elias", "last_name": "Baedorf Kassis", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 27914, "first_name": "TIMOTHY T", "last_name": "HOULE", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 771, "ror": "https://ror.org/04drvxt59", "name": "Beth Israel Deaconess Medical Center", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "/ ABSTRACT Acute respiratory distress syndrome (ARDS) occurs in up to one-quarter of all critically ill adults receiving mechanical ventilation and is associated with high risk of morbidity and mortality, which is compounded by ventilation-induced lung injury (VILI). Current ventilation strategies and standard care attempt to lessen the effects of VILI, but have not been uniformly successful. The need for improved ventilation strategies have become more compelling and urgent in the context of the COVID-19 pandemic. Precise ventilator titration of tidal volumes to maintain driving pressure ≤ 12 cm H2O may improve overdistension injury and application of positive end expiratory pressure (PEEP) with titration to transpulmonary pressure of 0±2cmH2O may prevent injury from lung collapse. This U24 grant application will establish a Data Coordinating Center (DCC) that supports the PREcision VENTilation to attenuate VILI Clinical Coordinating Center (CCC) in conducting a multicenter, prospective phase III randomized trial to test the hypothesis that this precision ventilation strategy will improve 60-day mortality compared to guided usual care in patients with moderate or severe ARDS. The DCC will provide the infrastructure, support, oversight and quality control necessary to conduct this trial guided by the following aims: Aim 1 - To collaborate in the protocol development. The DCC will assist the CCC in defining the overarching plan of the trial, and ensure the inclusion of essential sections within the protocol document. Aim 2 - To design and execute an appropriate, pre-determined, innovative statistical plan including analysis of study data, assessment of safety, investigation of mechanism of benefit, and facilitation of manuscript preparation. Aim 3 – To facilitate a patient centered study, with community engagement, by providing video-assisted consent materials, real-time reporting of accrual rates, with emphasis on ensuring a diverse participant population and ensuring patient safety by providing clear instructions on identification and timing of adverse event reporting and creation of the Data and Safety Monitoring Board. Aim 4 - To support an advanced physiological core laboratory to integrate physiological expertise into trial conduct and data management and to ensure rigor and reproducibility of respiratory waveform interpretation used for protocol-directed ventilator management in the intervention arm. The DCC will review all physiological waveforms submitted by sites and provide feedback regarding quality and interpretation. Aim 5 - To provide data administration and monitor trial activities. The DCC will build the eCRFs on a state-of-the-art electronic data capture system. During enrollment, the DCC will ensure high-quality data collection and measure and improve protocol compliance. To foster site communication and identity, the DCC will develop a trial website and quarterly newsletter, and assist the CCC in organizing meetings and conference calls. Aim 6 - To ensure completeness of the study and post-trial activities. This includes meeting milestones and end-of-trial support for participating sites and providing the funding agency with a finalized, deidentified, and locked data set for public use.", "keywords": [ "Acute Respiratory Distress Syndrome", "Address", "Admission activity", "Adult", "Adverse event", "Applications Grants", "Attenuated", "Automobile Driving", "Biological Markers", "Body Weight", "Breathing", "COVID-19 mortality", "COVID-19 pandemic", "Case Report Form", "Cause of Death", "Clinical", "Clinical Trials Data Monitoring Committees", "Collaborations", "Communication", "Consent", "Critical Illness", "Data", "Data Collection", "Data Coordinating Center", "Data Set", "Electronics", "Enrollment", "Ensure", "Feedback", "Fostering", "Funding Agency", "Goals", "Grant", "Healthcare Systems", "Infrastructure", "Injury", "Instruction", "Intervention", "Investigation", "Laboratories", "Lung", "Maintenance", "Manuscripts", "Measurement", "Measures", "Mechanical ventilation", "Methodology", "Monitor", "Morbidity - disease rate", "Newsletter", "Outcome", "Participant", "Patients", "Phase", "Physiological", "Population", "Positive-Pressure Respiration", "Preparation", "Prevention strategy", "Protocol Compliance", "Protocols documentation", "Quality Control", "Randomized Controlled Trials", "Recording of previous events", "Recovery", "Reporting", "Reproducibility", "Research", "Research Personnel", "Respiratory Mechanics", "Risk", "Shock", "Site", "Stress", "Techniques", "Teleconferences", "Testing", "Tidal Volume", "Time", "Titrations", "Ventilator", "Ventilator-induced lung injury", "arm", "atelectrauma", "community engagement", "cost", "data management", "design", "efficacy testing", "electronic data capture system", "evidence base", "expiration", "hemodynamics", "high risk", "high standard", "improved", "innovation", "lung injury", "lung pressure", "meetings", "mortality", "novel", "patient oriented", "patient safety", "personalized approach", "personalized strategies", "pre-pandemic", "pressure", "prevent", "primary outcome", "prospective", "protocol development", "randomized trial", "respiratory", "safety assessment", "standard care", "standard of care", "statistical center", "support tools", "symposium", "treatment arm", "treatment as usual", "trial planning", "usual care arm", "ventilation", "web site" ], "approved": true } }, { "type": "Grant", "id": "15437", "attributes": { "award_id": "5U24HL166784-02", "title": "2/2: PREcision VENTilation to attenuate Ventilation-Induced Lung Injury (PREVENT VILI)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Heart Lung and Blood Institute (NHLBI)" ], "program_reference_codes": [], "program_officials": [ { "id": 22589, "first_name": "CHRISTIAN RENE", "last_name": "Gomez", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-09-01", "end_date": "2030-08-31", "award_amount": 661149, "principal_investigator": { "id": 27913, "first_name": "Elias", "last_name": "Baedorf Kassis", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 27914, "first_name": "TIMOTHY T", "last_name": "HOULE", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 771, "ror": "https://ror.org/04drvxt59", "name": "Beth Israel Deaconess Medical Center", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "/ ABSTRACT Acute respiratory distress syndrome (ARDS) occurs in up to one-quarter of all critically ill adults receiving mechanical ventilation and is associated with high risk of morbidity and mortality, which is compounded by ventilation-induced lung injury (VILI). Current ventilation strategies and standard care attempt to lessen the effects of VILI, but have not been uniformly successful. The need for improved ventilation strategies have become more compelling and urgent in the context of the COVID-19 pandemic. Precise ventilator titration of tidal volumes to maintain driving pressure ≤ 12 cm H2O may improve overdistension injury and application of positive end expiratory pressure (PEEP) with titration to transpulmonary pressure of 0±2cmH2O may prevent injury from lung collapse. This U24 grant application will establish a Data Coordinating Center (DCC) that supports the PREcision VENTilation to attenuate VILI Clinical Coordinating Center (CCC) in conducting a multicenter, prospective phase III randomized trial to test the hypothesis that this precision ventilation strategy will improve 60-day mortality compared to guided usual care in patients with moderate or severe ARDS. The DCC will provide the infrastructure, support, oversight and quality control necessary to conduct this trial guided by the following aims: Aim 1 - To collaborate in the protocol development. The DCC will assist the CCC in defining the overarching plan of the trial, and ensure the inclusion of essential sections within the protocol document. Aim 2 - To design and execute an appropriate, pre-determined, innovative statistical plan including analysis of study data, assessment of safety, investigation of mechanism of benefit, and facilitation of manuscript preparation. Aim 3 – To facilitate a patient centered study, with community engagement, by providing video-assisted consent materials, real-time reporting of accrual rates, with emphasis on ensuring a diverse participant population and ensuring patient safety by providing clear instructions on identification and timing of adverse event reporting and creation of the Data and Safety Monitoring Board. Aim 4 - To support an advanced physiological core laboratory to integrate physiological expertise into trial conduct and data management and to ensure rigor and reproducibility of respiratory waveform interpretation used for protocol-directed ventilator management in the intervention arm. The DCC will review all physiological waveforms submitted by sites and provide feedback regarding quality and interpretation. Aim 5 - To provide data administration and monitor trial activities. The DCC will build the eCRFs on a state-of-the-art electronic data capture system. During enrollment, the DCC will ensure high-quality data collection and measure and improve protocol compliance. To foster site communication and identity, the DCC will develop a trial website and quarterly newsletter, and assist the CCC in organizing meetings and conference calls. Aim 6 - To ensure completeness of the study and post-trial activities. This includes meeting milestones and end-of-trial support for participating sites and providing the funding agency with a finalized, deidentified, and locked data set for public use.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "6538", "attributes": { "award_id": "3R34DA050291-01S2", "title": "2/7: Longitudinal evaluation of the impact of the COVID-19 pandemic on high-risk new and expectant mothers", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Drug Abuse (NIDA)" ], "program_reference_codes": [], "program_officials": [ { "id": 21898, "first_name": "Vani", "last_name": "Pariyadath", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2019-09-30", "end_date": "2021-03-31", "award_amount": 180332, "principal_investigator": { "id": 21899, "first_name": "Damien A", "last_name": "Fair", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 21900, "first_name": "Alice M", "last_name": "Graham", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 765, "ror": "https://ror.org/009avj582", "name": "Oregon Health & Science University", "address": "", "city": "", "state": "OR", "zip": "", "country": "United States", "approved": true }, "abstract": "The COVID-19 pandemic represents the most significant environmental event in living history and is leading to unprecedented social, economic and health consequences. There is an urgent need to longitudinally study the impact of the pandemic on pregnant women and the care they receive, and to understand the consequences for their children's birth outcomes and neurobehavioral development. Importantly, women with pre-existing substance use, mental health conditions and limited economic resources may be at increased risk for the wide- ranging, deleterious sequelae of the pandemic. The proposed project seeks to address these critical gaps by building upon ongoing harmonized research efforts across seven geographically-representative sites from the NIH HEALthy Brains and Cognitive Development study (HBCD) initiative, including New York University, Oregon Health Sciences University, Washington University in St. Louis, University of Pittsburgh, Cedars Sinai Medical Center, University of Vermont and Northwestern University. We will enroll pregnant and postpartum women into a multi-wave study in which we assess medical, economic, psychosocial and substance use risk across pregnancy and the perinatal period, studying associations of these factors to infant neurobehavioral development during the first year of life. Our central hypotheses include: 1) individual variation in perinatal COVID-19 related stress leads to differences in birth outcomes, parenting stress and infant temperament and neurodevelopment and 2) substance use, mental health and economic risk enhance susceptibility to negative COVID-19 related health and psychosocial outcomes. To pursue these aims, prospective longitudinal survey, birth and postpartum data will be obtained across a 3-month period in N=100 pregnant and new mothers per site (providing a total consortium sample of N=700) to generate individual temporal profiles of COVID-19 related experiences and responses, comparing outcomes with existing data from maternal-infant cohorts obtained prior to the pandemic. Further, to identify avenues for intervention, will evaluate substance use, poor mental health and low social economic status as risk factors and coping, agency and utilization of resources as resilience factors that influence COVID-19 related maternal stress and child health and neurobehavioral outcomes. The effects of geographic location will be used to examine the influence of pandemic severity, variation in local government policies and resource availability on these outcomes. Finally, we will collect and bank longitudinal perinatal biospecimens in N=40 women per site that will provide a foundation for future studies to evaluate the biological mechanisms through which the effects on maternal psychological and physical health influence offspring brain and behavioral development. Through this analysis of COVID-19 related stress, contextual factors and child outcomes, we will develop comprehensive understanding of effects and modifiers of this event on health outcomes in individuals that vary in dispositional risk during perinatal life, one of the most sensitive timepoints in human development.", "keywords": [ "Address", "Alcohol or Other Drugs use", "Apgar Score", "Behavioral", "Biological", "Biological Specimen Banks", "Biology", "Birth", "Birth Records", "Brain", "COVID-19", "COVID-19 pandemic", "Caring", "Child", "Child Health", "Child Rearing", "Childhood", "Cognitive", "Collection", "Communities", "Coping Behavior", "Data", "Data Set", "Development", "Developmental Delay Disorders", "Economics", "Emotional", "Enrollment", "Equation", "Event", "Exposure to", "Factor Analysis", "Foundations", "Future", "Gene Expression", "Geographic Locations", "Geography", "Gestational Age", "Health", "Health Sciences", "Healthcare", "Human", "Human Development", "Impact evaluation", "Individual", "Infant", "Institution", "Intervention", "Life", "Local Government", "Longitudinal Studies", "Longitudinal Surveys", "Longitudinal prospective study", "Low Birth Weight Infant", "Medical Economics", "Medical center", "Mental Health", "Modeling", "Mothers", "New York", "Oregon", "Outcome", "Parents", "Perinatal", "Policies", "Postpartum Period", "Postpartum Women", "Predisposition", "Pregnancy", "Pregnant Women", "Protocols documentation", "Proxy", "Psychological Stress", "Recording of previous events", "Research", "Resources", "Risk", "Risk Factors", "Sampling", "Severities", "Site", "Social support", "Specimen", "Stress", "Structure", "Surveys", "Testing", "Time", "Uncertainty", "United States National Institutes of Health", "Universities", "Variant", "Vermont", "Viral", "Virus", "Vulnerable Populations", "Washington", "Woman", "Work", "behavioral health", "brain health", "cognitive development", "cohort", "contextual factors", "coping", "coronavirus disease", "experience", "health economics", "high risk", "improved", "indexing", "individual variation", "infant temperament", "inflammatory marker", "interest", "maternal stress", "maternal weight", "microbiome", "neurobehavioral", "neurodevelopment", "offspring", "pandemic disease", "perinatal period", "physical conditioning", "postnatal", "pregnant", "prenatal", "prospective", "protective factors", "psychosocial", "public health emergency", "resilience", "response", "secondary analysis", "social", "stressor" ], "approved": true } }, { "type": "Grant", "id": "5352", "attributes": { "award_id": "0710685", "title": "2007 Electrochemistry GRC - GOALI: Gordon Research Conference Activities to Stimulate University-Industry-Government Laboratory Partnerships and Increase Diversity in Science", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "OFFICE OF MULTIDISCIPLINARY AC" ], "program_reference_codes": [], "program_officials": [], "start_date": "2007-01-15", "end_date": "2007-12-31", "award_amount": 20000, "principal_investigator": { "id": 18780, "first_name": "Carol", "last_name": "Korzeniewski", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 18779, "first_name": "Peter T", "last_name": "Kissinger", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "This GOALI award enables participation by a significant number of female and underrepresented minority scientists in the 2007 Gordon Research Conference (GRC) on Electrochemistry that will be held in Ventura, CA, January 14 - 19, 2007. Additionally, this award provides support for two half-day 'mini-workshops', embedded within the GRC program structure, that focus on two important facets of the American Competitiveness Initiative (ACI), namely (1) partnerships among academia, industry, and national laboratories and (2) development of a diverse, well prepared workforce, and do so within the critical technology of fundamental and applied electrochemistry.\n\nBroader impacts of this activity include seeding the development of (1) a diverse workforce in the electrochemical sciences and (2) new partnerships that capture sector synergy in multidisciplinary electrochemical sciences in pursuit of ACI goals.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "5351", "attributes": { "award_id": "0904257", "title": "2009 Gordon Research Conference on Thin Film and Crystal Growth Mechanisms; New London, NH; Summer 2009", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "BIOMATERIALS PROGRAM" ], "program_reference_codes": [], "program_officials": [], "start_date": "2008-12-15", "end_date": "2009-11-30", "award_amount": 5000, "principal_investigator": { "id": 18778, "first_name": "Jonah", "last_name": "Erlebacher", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "ID: MPS/DMR/BMAT(7623) 0904257 PI: Erlebacher, Jonah ORG: Gordon Research Conferences\n\nTitle: 2009 Gordon Research Conference on Thin Film and Crystal Growth\n\nINTELLECTUAL MERIT: The 2009 Gordon Research Conference on Thin Films and Crystallization addresses the fundamental issues underlying processes associated with crystal growth, which is central to a broad array of technologies. The conference will attract scientists from a wide range of disciplines, from semiconductor thin film growth to biocrystallization and crystallization for pharmaceutical drug delivery. Sessions devoted to the following timely topics are included: crystal surface morphology and kinetics, low dimensional crystals, fundamentals of crystal nucleation and growth, large biomolecule crystallization, biocrystallization and biomineralization, organic electronics, advanced electron microscopy, and structure function relationships on catalytic crystal surfaces. These topics intersect the portfolios of the NSF Biomaterials and Solid State and Materials Chemistry programs, which will provide partial support for the Conference..\n\nBROADER IMPACTS: The Gordon Research Conferences have a long standing reputation for providing an informal atmosphere for intimate scientific exchange among scientists from around the world. The plans for this conference fit this mold very well. The Vice-Chair and at least 6 of the 19 invited speakers are females. Participation in the Conference is by invitation, and the organizers describe a plan to ensure participation from a diverse selection of scientists, including especially women, racial and ethnic minorities, persons with disabilities, and others from groups that have been traditionally underrepresented in science. NSF support will help to facilitate participation by young scientists who might otherwise be unable to attend. The organizers have given due attention in the expenditure of support funds provided to further the NSF goals of broadening participation and integration of research and education.", "keywords": [], "approved": true } } ], "meta": { "pagination": { "page": 5, "pages": 1442, "count": 14420 } } }