Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=4&sort=program_officials
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=program_officials", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1419&sort=program_officials", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=5&sort=program_officials", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=3&sort=program_officials" }, "data": [ { "type": "Grant", "id": "10343", "attributes": { "award_id": "1S06GM146079-01", "title": "Strengthening COVID-19 prevention strategies via wastewater surveillance in a Northern Plains Tribe", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of General Medical Sciences (NIGMS)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-09-01", "end_date": "2026-07-31", "award_amount": 516672, "principal_investigator": { "id": 26306, "first_name": "Jeffrey A", "last_name": "Henderson", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1920, "ror": "", "name": "BLACK HILLS CTR/AMERICAN INDIAN HEALTH", "address": "", "city": "", "state": "SD", "zip": "", "country": "United States", "approved": true }, "abstract": "Despite the abundance of clinical and epidemiologic data collected during this pandemic, relatively little focus has been paid to the examination of infectious agents through bulk wastewater detection and epidemiological data that is particularly well-suited for disease surveillance in remote, frontier settings such as the CRST Reservation. The goal of this application is to develop and implement a 15-community wastewater testing program for viral contaminants, including SARS-CoV-2, to better understand the utility of wastewater testing and COVID-19 or other viral outbreaks in this remote, low-resourced, and relatively low-density Tribal community. We will use our highly collaborative, multidisciplinary team of Native investigators to develop and implement, and evaluate the effectiveness of a viral wastewater sequencing testing program in a very rural and remote Northern Plains Lakota Reservation. Therefore, we propose to leverage our 20-year, long-running partnership with CRST to address the following Specific Aims: 1. Use a highly participatory approach to design, garner approval for, and implement a wastewater testing system in a large Tribal reservation community. This community surveillance approach will screen for viral isolates, including SARS-CoV-2, in coordination with CRST’s preexisting COVID-19 surveillance system; and 2. Deploy qualitative methods to examine 16 key Tribal stakeholders’ and Tribal members’ attitudes towards this new community wastewater testing approach and, ultimately, how this new environmental testing effort affects Tribal members socially, ethically, and behaviorally; and 3. Seek to codify this new resource into the Tribe’s public health emergency response program, thereby enhancing the Tribe’s capacity for future viral and other likely epidemic and pandemic outbreaks.", "keywords": [ "2019-nCoV", "Address", "Affect", "Alaska Native", "American Indians", "Attitude", "Behavioral", "Businesses", "COVID-19", "COVID-19 pandemic", "COVID-19 prevention", "COVID-19 surveillance", "Cessation of life", "Cheyenne", "Chronic", "Clinical Data", "Color", "Communicable Diseases", "Communities", "Coronavirus", "Detection", "Diagnostic Reagent Kits", "Disease", "Disease Outbreaks", "Disease Surveillance", "Emergency response", "Environmental Impact", "Environmental Monitoring", "Epidemic", "Ethics", "Ethnic group", "Future", "Generations", "Geographic state", "Goals", "Health", "Housing", "Incidence", "Indian reservation", "Infectious Agent", "Infrastructure", "Knowledge", "Mind", "Northern Plains Tribe", "Prevention strategy", "Process", "Qualitative Methods", "Research", "Research Personnel", "Reservations", "Resources", "Rivers", "Running", "Rural", "Schools", "Sioux Indians", "Smallpox", "South Dakota", "Spanish flu", "Speed", "Surveillance Program", "System", "Testing", "Teton Sioux Indian", "Thinking", "Travel", "Tribes", "United States", "United States Indian Health Service", "Viral", "Virus", "density", "design", "effectiveness evaluation", "epidemiologic data", "experience", "frontier", "multidisciplinary", "northern plains", "novel coronavirus", "pandemic disease", "personal protective equipment", "programs", "public health emergency", "racial and ethnic", "screening", "social", "tribal community", "tribal leader", "tribal member", "wastewater surveillance", "wastewater testing" ], "approved": true } }, { "type": "Grant", "id": "5274", "attributes": { "award_id": "0814552", "title": "Group Travel Support for International Conference on Inverse Problems", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "TTP-Thermal Transport Process" ], "program_reference_codes": [], "program_officials": [], "start_date": "2008-05-01", "end_date": "2009-04-30", "award_amount": 10200, "principal_investigator": { "id": 18587, "first_name": "Guy", "last_name": "Raguin", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 521, "ror": "https://ror.org/05hs6h993", "name": "Michigan State University", "address": "", "city": "", "state": "MI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 18586, "first_name": "Neil T", "last_name": "Wright", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 521, "ror": "https://ror.org/05hs6h993", "name": "Michigan State University", "address": "", "city": "", "state": "MI", "zip": "", "country": "United States", "approved": true }, "abstract": "CBET-0814552\nRaguin\n\nPartial support is provided for US participation in the Sixth International Conference on Inverse Problems in Engineering (6th ICIPE), which will be held in Dourdan, France, on June 15 - 19, 2008. The purpose of this meeting is to enable US researchers to become more engaged in this field, which is being led by researchers from outside the US.\n\nWith respect to the intellectual merit of the conference, inverse problems impact a wide variety of interdisciplinary engineering fields, including (but not limited) to thermal transport. Significant advances have been made primarily outside the US, indicating that US researchers are lagging their international counterparts. It is thus very important for US researchers to be involved with this meeting, particularly junior investigators.\n\nThe broader impacts of the conference include support for a number of junior, female, and under-represented minority researchers to attend this meeting. A key goal of the conference is to enhance international collaboration opportunities. Results from the meeting will be disseminated by publication in the Journal of Physics: Conference Series, an open-access web-based journal.\n\nThis project is funded by the Thermal Transport Processes (TTP) Program of the Chemical, Bioengineering, Environmental, and Transport Systems (CBET) Division.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "5351", "attributes": { "award_id": "0904257", "title": "2009 Gordon Research Conference on Thin Film and Crystal Growth Mechanisms; New London, NH; Summer 2009", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "BIOMATERIALS PROGRAM" ], "program_reference_codes": [], "program_officials": [], "start_date": "2008-12-15", "end_date": "2009-11-30", "award_amount": 5000, "principal_investigator": { "id": 18778, "first_name": "Jonah", "last_name": "Erlebacher", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "ID: MPS/DMR/BMAT(7623) 0904257 PI: Erlebacher, Jonah ORG: Gordon Research Conferences\n\nTitle: 2009 Gordon Research Conference on Thin Film and Crystal Growth\n\nINTELLECTUAL MERIT: The 2009 Gordon Research Conference on Thin Films and Crystallization addresses the fundamental issues underlying processes associated with crystal growth, which is central to a broad array of technologies. The conference will attract scientists from a wide range of disciplines, from semiconductor thin film growth to biocrystallization and crystallization for pharmaceutical drug delivery. Sessions devoted to the following timely topics are included: crystal surface morphology and kinetics, low dimensional crystals, fundamentals of crystal nucleation and growth, large biomolecule crystallization, biocrystallization and biomineralization, organic electronics, advanced electron microscopy, and structure function relationships on catalytic crystal surfaces. These topics intersect the portfolios of the NSF Biomaterials and Solid State and Materials Chemistry programs, which will provide partial support for the Conference..\n\nBROADER IMPACTS: The Gordon Research Conferences have a long standing reputation for providing an informal atmosphere for intimate scientific exchange among scientists from around the world. The plans for this conference fit this mold very well. The Vice-Chair and at least 6 of the 19 invited speakers are females. Participation in the Conference is by invitation, and the organizers describe a plan to ensure participation from a diverse selection of scientists, including especially women, racial and ethnic minorities, persons with disabilities, and others from groups that have been traditionally underrepresented in science. NSF support will help to facilitate participation by young scientists who might otherwise be unable to attend. The organizers have given due attention in the expenditure of support funds provided to further the NSF goals of broadening participation and integration of research and education.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "4878", "attributes": { "award_id": "1135231", "title": "Social Science and the Alternative Energy Future: A Workshop Proposal to the National Science Foundation", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "Cross-Directorate Activities" ], "program_reference_codes": [], "program_officials": [], "start_date": "2011-06-01", "end_date": "2012-05-31", "award_amount": 50000, "principal_investigator": { "id": 17568, "first_name": "Leslie", "last_name": "Berlowitz", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1351, "ror": "", "name": "American Academy of Arts and Sciences (AAAS)", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 17566, "first_name": "", "last_name": "", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 17567, "first_name": "Robert W", "last_name": "Fri", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 1351, "ror": "", "name": "American Academy of Arts and Sciences (AAAS)", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "American Academy of Arts and Sciences\nSocial Science and the Alternative Energy Future: A workshop proposal to the National Science Foundation\n\nPROJECT SUMMARY\nThere is a critical need to identify the legal, social, and economic barriers to the adoption of new energy technologies and to assess how they might be better understood and managed using tools developed by the social sciences. To address this need, the American Academy will convene a workshop on \"Social Science and the Alternative Energy Future\" on May 19-20, 2011, in Washington, D.C., that will identify priority areas for future social science research and develop recommendations for bridging the gap between the energy and the social science communities. The workshop will bring together social scientists, scientists and engineers, legal scholars, business leaders, and government officials to investigate issues that will benefit from further social science research and to understand how social science expertise can be more effectively applied to the development of energy policy.\n\nIntellectual Merit: Previous studies from the National Academies and others have concluded that the energy system must undergo transformational change to ensure an affordable, secure, and sustainable energy system. Transformational change of the existing technological infrastructure will require changes to economic, social, and legal structures as well, yet many of the societal considerations underlying these necessary changes have not been adequately addressed. This workshop will consider four key issues that will require new thinking from social scientists in order to meet the needs of policy-makers, and that have not been adequately addressed by other studies:\n\n1. How will the transformation of the energy system affect the decisions made by individuals and communities?\n2. How do regulations need to change to support new energy technologies?\n3. What governance framework will help sustain energy policies over the long term?\n4. What will be the effect of changing the energy system on other physical systems, including ecosystems and natural resources?\n\nBroader Impact: The final workshop report will review existing social science research, identify priority areas for future research, and develop recommendations for increasing communication between social scientists and energy policy-makers. By creating new interdisciplinary collaborations between previously-isolated professional communities, this workshop will inform governmental policy development and the research initiatives of nongovernmental organizations, and will increase public awareness of the societal risks and benefits of alternative energy technologies.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "11445", "attributes": { "award_id": "272201700014C-P00023-9999-2", "title": "COVID-19: NIAID Regulatory Support Center", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2023-04-15", "end_date": "2024-04-14", "award_amount": 5439404, "principal_investigator": { "id": 25151, "first_name": "ASIMAH", "last_name": "RAFI", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1608, "ror": "", "name": "TECHNICAL RESOURCES INTERNATIONAL, INC.", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1608, "ror": "", "name": "TECHNICAL RESOURCES INTERNATIONAL, INC.", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true }, "abstract": "The purpose of this contract is to provide regulatory expertise and support to operate and manage the NIAID Regulatory Support Center (RSC) to provide a wide range of clinical research activities and programs for NIAID. The RSC provides comprehensive regulatory support to: 1) perform NIAID-funded and NIAID-sponsored domestic and international clinical trial research; 2) provide training in key functions of clinical trial research to NIAID staff, investigators, and collaborators; and 3) maintain all contract-associated data and records in the NIAID-Clinical Research Management System (N-CRMS), including the electronic submission of required regulatory information. This project will provide regulatory support services for the COVID-19 clinical trial ACTIV-2 (Outpatient Monoclonal Antibodies And Other Therapies).", "keywords": [ "Agreement", "COVID-19", "Clinical Research", "Clinical Trials", "Contracts", "Data", "Electronics", "Funding", "International", "Investigational New Drug Application", "Monoclonal Antibodies", "National Institute of Allergy and Infectious Disease", "Outpatients", "Preparation", "Protocols documentation", "Records", "Research", "Research Activity", "Research Personnel", "Review Committee", "Services", "System", "Training", "clinical application", "human subject protection", "meetings", "programs" ], "approved": true } }, { "type": "Grant", "id": "10867", "attributes": { "award_id": "1I01HX003574-01", "title": "Impact of COVID-era Disrupted Care on Disparities in Outcomes among Veterans with Kidney Failure", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [], "start_date": "2022-08-01", "end_date": "2024-07-31", "award_amount": null, "principal_investigator": { "id": 12730, "first_name": "AMAL N.", "last_name": "TRIVEDI", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 26960, "first_name": "Virginia", "last_name": "Wang", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 1827, "ror": "https://ror.org/034adnw64", "name": "Durham VA Medical Center", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "Background: The COVID-19 pandemic significantly disrupted care delivery that limited access to providers, acute and timely non-acute evaluation, and clinical intervention. Dialysis patients with kidney failure are particularly vulnerable to COVID-19 infection, COVID-19 related morbidity and mortality because they commonly have multiple chronic conditions, typically require thrice weekly life-sustaining dialysis treatment in close- quartered clinic settings, are already prone to fragmented care, and especially susceptible to disrupted care. The COVID-19 pandemic presents fundamental threats to dialysis patients, and there is an urgent need to examine the impact of disrupted care for this vulnerable and uniquely healthcare reliant population of patients. Over 16,000 of enrolled Veterans receive chronic dialysis through Veterans Health Administration (VA) Kidney Program’s VA and VA Community Care providers. VA Community Care improves access to life- sustaining dialysis services for 80% of Veterans with kidney failure with limited access to the VHA’s 70 dialysis units. In prior work, we found lower 2-year mortality among Veterans receiving dialysis exclusively in VA compared to those receiving dialysis in non-VA settings, consistent with VA and non-VA comparative studies in other clinical contexts. These differences may be due to more comprehensive integrated services (e.g., co- located primary and tertiary care services, care management, social work, national electronic medical record) in VA, compared with the more fragmented and siloed dialysis care in private sector community settings. Significance: Pandemic-related disruptions may disproportionately affect Veterans with serious conditions and social risk factors like those with kidney failure and the nature and impact of pandemic-related disruptions may differ in VA and non-VA systems. However, rigorous comparisons of COVID-related care disruptions and outcomes between Veterans receiving healthcare in VA and non-VA settings are lacking. Specific Aims: Building on our team’s research expertise, this study will: 1) Quantify the impact of COVID-19 on 1a) disrupted care for prevalent patients and 1b) deferred care for incident patients in a national cohort of Veterans with ESKD and compare the extent of these impacts between VA- financed dialysis care in VA and VA Community Care settings from 2018-2022. 2) Compare patient-level outcomes and racial and socioeconomic disparities in outcomes in VA and non-VA dialysis settings before and during the COVID pandemic time periods. Methodology: We will conduct a longitudinal cohort study of all VA-enrolled patients with end-stage kidney disease receiving VA-financed dialysis care between 2018 and 2022, to observe care patterns before the pre- COVID phase (Jan 2018-Feb 2020), the acute COVID phase defined as the first case of COVID until authorization of the vaccine (Mar 2020-Dec 2020) and the recovery phase when COVID-19 vaccination was available (Jan 2021-Dec 2022). Study data will be derived from linkages of VA and Medicare administrative data with community-level national COVID-19 tracking and neighborhood socioeconomic status data to assess the impacts of pandemic-related disruptions in care on disparities in outcomes among Veterans receiving dialysis in VA and non-VA settings. Next Steps/Implementation: This research is directly responsive to the COVID RFA HX-21-025: Pandemic related disrupted and deferred care and three VA HSR&D priority areas (Access to Care, Complex Disease Management, Social Determinants of Health). The study team is conducting this work partnership with the VHA National Program for Kidney Disease to ensure that our work is poised to shape evolving VA policy around provision of community care and to improve care for Veterans during the COVID-19 pandemic, recovery, and future public health crises. Results will inform how VA manages its Veterans in disaster scenarios, particularly with provider partners in VA community care, for whom the VA relies on for reliable and accessible dialysis care.", "keywords": [ "Acute", "Address", "Affect", "Ambulatory Care", "Area", "Authorization documentation", "Blood Vessels", "COVID-19", "COVID-19 impact", "COVID-19 morbidity", "COVID-19 pandemic", "COVID-19 vaccination", "Caring", "Chronic", "Clinic", "Clinical", "Collaborations", "Communities", "Community Financing", "Comparative Study", "Complex", "Computerized Medical Record", "Critical Care", "Data", "Dedications", "Diagnostic", "Dialysis patients", "Dialysis procedure", "Disasters", "Disease Management", "Emergency Situation", "End stage renal failure", "Enrollment", "Ensure", "Evaluation", "Frequencies", "Future", "Health", "Health Personnel", "Health Services Accessibility", "Health Services Administration", "Healthcare", "Immunocompromised Host", "Improve Access", "Integrated Health Care Systems", "Intervention", "Kidney", "Kidney Diseases", "Kidney Failure", "Life", "Longitudinal cohort study", "Maintenance", "Managed Care", "Medicare", "Methodology", "Morbidity - disease rate", "Nature", "Neighborhoods", "Outcome", "Patient Transfer", "Patients", "Patterns of Care", "Phase", "Policies", "Predisposition", "Primary Care", "Private Sector", "Procedures", "Process", "Provider", "Public Health", "Recovery", "Renal function", "Research", "Resources", "Risk Factors", "SARS-CoV-2 exposure", "SARS-CoV-2 infection", "Services", "Shapes", "Social Work", "Socioeconomic Status", "Structure", "Survival Rate", "System", "Time", "Vaccines", "Veterans", "Veterans Health Administration", "Work", "authority", "base", "care delivery", "care fragmentation", "care providers", "care systems", "cohort", "community setting", "coronavirus disease", "disadvantaged population", "ethnic minority", "experience", "health equity", "improved", "medical specialties", "military veteran", "mortality", "multiple chronic conditions", "pandemic disease", "participant enrollment", "patient population", "programs", "racial and ethnic", "social", "social health determinants", "socioeconomic disadvantage", "socioeconomic disparity", "tertiary care", "treatment adherence" ], "approved": true } }, { "type": "Grant", "id": "10787", "attributes": { "award_id": "1I01HX003576-01A1", "title": "Impact of COVID-19 on Continuity of Care for Veterans on Antipsychotic Medications", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [], "start_date": "2022-11-01", "end_date": "2024-10-31", "award_amount": null, "principal_investigator": { "id": 26863, "first_name": "ANOUK L", "last_name": "GRUBAUGH", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1782, "ror": "", "name": "RALPH H JOHNSON VA MEDICAL CENTER", "address": "", "city": "", "state": "SC", "zip": "", "country": "United States", "approved": true }, "abstract": "Background: Severe mental illnesses are consistently ranked as some of the most debilitating health conditions worldwide due to their early age of onset, chronicity, and impact on functioning. Fortunately, a number of antipsychotic medications have been found to be effective for managing the symptoms of severe mental illness (SMI) and for preventing relapse and rehospitalization. Despite their efficacy, treatment non-compliance for individuals on these medications is high due to a number of factors including poor insight into illness, negative attitudes about medication, and medication related side effects. Further complicating care and outcomes for this clinical population, providers must maintain close oversight of patients on antipsychotics due to the impact of these medications on metabolic and cardiac functioning which confer an increased risk of obesity, diabetes, heart problems, and other chronic illnesses. This oversight includes regular monitoring of weight, blood pressure, fasting blood glucose, and lipid levels. Additionally, clozapine, indicated for treatment-resistant schizophrenia, requires weekly-to-monthly monitoring of absolute neutrophil counts to prevent potentially fatal clozapine- induced agranulocytosis. Significance: The proposed project has significant and immediate relevance to Veterans and the VHA in that it seeks to better understand if and to what extent COVID-19 related care disruptions impacted care and outcomes for Veterans with SMI prescribed antipsychotic medications. Given pre- existing challenges in the treatment of this Veteran population, this is an important area of inquiry as well as one for which little is known. Added strengths of the proposed study include the use of a mixed methods approach that includes national level data from multiple sources. Aside from addressing a critical knowledge gap, the proposed study targets what is unarguably one of the most vulnerable patient populations within the VA and other healthcare systems—patients with SMI prescribed antipsychotic medications. Specific Aims: Aim 1: To assess the impact of COVID-19 related care disruptions on healthcare use and outcomes for Veterans on antipsychotic medications using robust statistical methods and national level data; Aim 2: To assess whether the impact of COVID-19 related care disruptions differ by race/ethnicity, gender, age, and rural/urban status using national level data; Aim 3: To conduct thematic interviews with provider and patient stakeholder groups at the national level to better understand COVID-19 related care disruptions. Provider stakeholders (e.g., psychiatrists, advanced nurse practitioners) will be interviewed to better understand COVID-19 related changes in practice behaviors, the perceived impact of these changes on care continuity and outcomes, and to solicit suggestions to mitigate the impact of interrupted care in the future; Veterans prescribed antipsychotic medication prescriptions in the pre COVID-19 window will be interviewed to better understand the impact of COVID-19 related care disruptions on treatment seeking behaviors, obstacles encountered with regard to access, and to explore other factors potentially impacting outcomes in this patient group. Methodology: The proposed study will employ a mixed-methods (quantitative/qualitative) approach. For Aims 1 & 2 we will employ retrospective, observational analyses using a national cohort of Veterans (N>250,000) with an ICD-CM-10 diagnostic code for schizophrenia or bipolar disorder prescribed a first-generation or second-generation antipsychotic [1/19-12/21]. Veterans of all ages, genders, racial groups, military eras will be included in the cohort. Aim 3 will involve individual thematic interviews with provider (n=35-45) and patient stakeholders (n=50-60). Next Steps/Implementation: Findings from this 2-year project will be of immediate relevance and impact for local, regional, and national level administrators and mental health providers as well as the VA Office of Mental Health and Suicide Prevention and VA Pharmacy Benefits Management Services. Collectively, data from this project will serve to identify potential strategies to further mitigate the impact of COVID-19 on the care and outcomes of Veterans with SMI as well as prepare for future public health and/or other national emergencies.", "keywords": [ "Address", "Adherence", "Administrator", "Admission activity", "Age", "Age of Onset", "Agranulocytosis", "Antipsychotic Agents", "Area", "Attitude", "Behavior", "Bipolar Disorder", "Blood Glucose", "Blood Pressure", "COVID-19", "COVID-19 impact", "Caring", "Chronic", "Chronic Disease", "Clinical", "Clozapine", "Code", "Continuity of Patient Care", "Data", "Data Sources", "Diabetes Mellitus", "Diagnostic", "Disease", "Drug Prescriptions", "Emergency Care", "Emergency Situation", "Ethnic Origin", "Event", "Fasting", "Future", "Gender", "Generations", "Guidelines", "Health", "Health Personnel", "Healthcare", "Healthcare Systems", "Heart", "Heart Diseases", "Individual", "Inpatients", "Interruption", "Interview", "Knowledge", "Lipids", "Malignant Neoplasms", "Mental Health", "Mental disorders", "Metabolic", "Methodology", "Methods", "Military Personnel", "Minority Women", "Monitor", "Nurse Practitioners", "Outcome", "Outpatients", "Patients", "Pharmaceutical Preparations", "Pharmacists", "Population", "Provider", "Psychiatrist", "Public Health", "Race", "Relapse", "Research Design", "Resistance", "Rural", "Safety", "Schizophrenia", "Services", "Statistical Methods", "Suggestion", "Suicide", "Suicide prevention", "System", "Testing", "Time", "Veterans", "Visit", "Weight", "behavioral outcome", "care outcomes", "cohort", "cost", "economic impact", "experience", "health care availability", "health care delivery", "health care service utilization", "heart function", "hospital readmission", "insight", "military veteran", "mortality", "multiple data sources", "neutrophil", "non-compliance", "obesity risk", "patient population", "pharmacy benefit", "post-COVID-19", "prevent", "racial and ethnic", "rural area", "severe mental illness", "side effect", "symptom management", "urban dwelling" ], "approved": true } }, { "type": "Grant", "id": "4897", "attributes": { "award_id": "1114183", "title": "2011 Chemical Oceanography Gordon Research Conference", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "Chemical Oceanography" ], "program_reference_codes": [], "program_officials": [], "start_date": "2011-07-15", "end_date": "2012-06-30", "award_amount": 37000, "principal_investigator": { "id": 17631, "first_name": "David", "last_name": "Burdige", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 17630, "first_name": "Nancy R", "last_name": "Gray", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 226, "ror": "https://ror.org/05rad4t93", "name": "Gordon Research Conferences", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "A major objective of the Chemical Oceanography Gordon Research Conference is to bring together every two years leading members of the scientific community, graduate students, and post docs to discuss new, cutting-edge research projects in marine chemistry within an informal setting. In 2011, the Chemical Oceanography Gordon Research Conference will be held August 14-19, 2011 at Proctor Academy in New Hampshire. The theme for this year's conference will be \"Linking the Time and Space Scales of Chemical Oceanography\" and will emphasize the need to comprehend the response of the ocean to anthropogenic forcing within the context of a mechanic understanding of the underlying processes and an historical perspective for how the processes have changed over time. The primary goal of the conference is to provide a forum that brings together scientists that are leading contributors in the field of marine chemistry and graduate students/postdocs to exchange ideas on new, innovative research. Presentations and discussions at the 2011 Gordon Conference will center around the following session topics: (1) The Gulf of Mexico Oil Spill: A Status Report; (2) The Marine Phosphorus Cycle: Past, Present and Future; (3) New Insights Into the Marine Nitrogen Cycle; (4) Chemical Oceanography in Deep Time; (5) Glacial-Interglacial Changes in Ocean Chemistry; (6) Trace Element Cycling in the Oceans: Biotic Influences and Responses; (7) Submarine Groundwater Discharge; (8) Carbon Processing in the Coastal Ocean; and (9) Benthic Biogeochemical Processes Across Space and Time. The Chemical Oceanography Gordon Research Conference has become recognized as an important venue to exchange ideas in the interdisciplinary field of marine chemistry and to forge new scientific alliances. For this reason, the National Science Foundation, along with the Gordon Research Conference, will co-sponsor the participation of at least 17 graduate student/post docs and 33 invited speakers/discussion leaders/chairs in the 2011 Chemical Oceanography Gordon Research Conference.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "11718", "attributes": { "award_id": "1I21RX004371-01A1", "title": "Fatigue and Fatigability in Veterans Following SARS-CoV-2 Infection", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [], "start_date": "2023-07-01", "end_date": "2025-06-30", "award_amount": null, "principal_investigator": { "id": 27588, "first_name": "JARED M.", "last_name": "GOLLIE", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 2041, "ror": "", "name": "U.S. DEPT/VETS AFFAIRS MEDICAL CENTER", "address": "", "city": "", "state": "DC", "zip": "", "country": "United States", "approved": true }, "abstract": "The chronic presence of elevations in fatigue suggests that individuals with post-COVID-19 fatigue (PCF) may be at risk for experiencing increased fatigability when engaging in physical activity. An individual’s level of fatigability is determined by the interactions between objective declines in performance (performance fatigability) and perceptual changes regulating activity performance (i.e., perceived fatigability). Skeletal muscle alterations including reduced force capacity, fiber atrophy, and metabolic dysfunction have been observed in patients following SARS-CoV-2 infection. In addition, depression and anxiety have been identified as common pre-existing conditions in patients with PCF. Thus, psychological as well as physiological consequences of SARS-CoV-2 may provide insight into co-occurring mechanisms by which increased fatigability occurs and persists following SARS-CoV-2 infection. While there have been widespread calls for the implementation of rehabilitation for individuals recovering from SARS-CoV-2 infection, relatively little is known about the potential benefits of physical exercise in this population. Home-based exercise programs maybe particularly advantageous due to its ability to provide an exercise option to combat sedentary behavior imposed by lockdowns, quarantines, and restrictions on community activity caused by the COVID-19 pandemic. To date, the safety and feasibility of home-based exercise has yet to be thoroughly investigated in people previously infected by SARS-CoV-2. The overall goal of this project is to advance our understanding of underlying mechanisms impacting performance fatigability and perceived fatigability in Veterans with PCF and explore the safety and feasibility of a home-based “minimal-dose” resistance exercise program in this population. The central hypothesis is that declines in force capacity, skeletal muscle oxygen extraction, and affective responses to physical activity offer potential mechanisms through which fatigability is increased in Veterans with PCF. Moreover, home-based resistance exercise delivered remotely may provide a safe and feasible treatment option for this population. To address this hypothesis, the following aims are proposed: Aim 1: Compare fatigability, and the underlying neuromuscular and neurobiological factors, in Veterans with post- COVID-19 fatigue to Veterans previously infected by SARS-CoV-2 without fatigue. Hypothesis 1a. Veterans with post-COVID-19 fatigue will exhibit greater performance fatigability and perceived fatigability compared to Veterans previously infected with SARS-CoV-2 not reporting post-COVID-19 fatigue. Hypothesis 1b. Veterans with post-COVID-19 fatigue will exhibit reductions in knee extensor force capacity, muscle oxygen extraction, and affective valence compared to Veterans previously infected with SARS-CoV-2 not reporting post-COVID-19 fatigue. Aim 2: Determine the safety and feasibility of an 8-week home-based “minimal-dose” resistance exercise program for Veterans with post-COVID-19 fatigue. Hypothesis 2a. 8 weeks of home-based minimal- dose resistance exercise will be safe and feasible in Veterans with post-COVID-19 fatigue. To test aim 2, we will use a randomized controlled feasibility trial. Skeletal muscle force will be assessed during isometric and dynamic knee extensor contractions using dynamometry and muscle oxygen extraction of the vastus lateralis will be estimated using near-infrared spectroscopy. Affective responses will be measured using the Feeling Scale. Secondary measures include motor unit properties, functional outcomes, and health-related quality of life.", "keywords": [ "2019-nCoV", "Address", "Affective", "Anxiety", "Atrophic", "Award", "Awareness", "COVID-19 pandemic", "Chronic", "Clinical", "Clinical Trials", "Communities", "Data", "Dose", "Effectiveness", "Exercise", "Exhibits", "Extensor", "Fatigue", "Feeling", "Fiber", "Goals", "Health", "Home", "Individual", "Isometric Exercise", "Knee", "Measures", "Mental Depression", "Metabolic dysfunction", "Motor", "Muscle", "Near-Infrared Spectroscopy", "Neurobiology", "Oxygen", "Patients", "Performance", "Persons", "Physical Exercise", "Physical activity", "Physiological", "Population", "Prevalence", "Property", "Quarantine", "Randomized", "Rehabilitation therapy", "Reporting", "Risk", "SARS-CoV-2 infection", "Severities", "Skeletal Muscle", "Symptoms", "Testing", "Veterans", "appropriate dose", "base", "combat", "design", "exercise program", "experience", "feasibility trial", "functional outcomes", "health related quality of life", "improved", "insight", "neurobehavioral", "neuromuscular", "novel", "patient population", "post SARS-CoV-2 infection", "post-COVID-19", "psychologic", "remote delivery", "resistance exercise", "response", "safety and feasibility", "sedentary lifestyle", "skeletal muscle weakness", "vastus lateralis" ], "approved": true } }, { "type": "Grant", "id": "3670", "attributes": { "award_id": "1700152", "title": "Increasing the Student Biotech Pipeline", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "Advanced Tech Education Prog" ], "program_reference_codes": [], "program_officials": [], "start_date": "2017-05-01", "end_date": "2021-04-30", "award_amount": 199980, "principal_investigator": { "id": 11960, "first_name": "Parvaneh", "last_name": "Mohammadian", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 11959, "first_name": "Stephen T", "last_name": "Brown", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 459, "ror": "https://ror.org/01stcbz02", "name": "Los Angeles Mission College", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "Los Angeles Mission College (LAMC) will prepare community college and high school students for jobs in biotechnology. The new programs developed will explicitly address skill development and offer students counseling, tutoring, industry field trips, external speakers, and internship opportunities. Combined with excellent instruction in the classroom, these activities will prepare students for entry-level, middle-skill technician positions. LAMC serves a large underrepresented student body and will provide these students with employment opportunities in a high growth sector that needs a skilled workforce. Project evaluation will focus on measuring student progression, success, retention, and degree attainment.\n\nLAMC will develop new academic pathways and curricula in biotechnology leading to stackable certificates and an Associate of Science degree. Stackable credentials will prepare students to enter the workforce in a short period of time while retaining the opportunity to pursue higher degrees at a later date. It will also allow for flexibility that will contribute to student retention and success. The project will provide high school students an opportunity to earn college credit and credentials that will ultimately assist them in obtaining employment.", "keywords": [], "approved": true } } ], "meta": { "pagination": { "page": 4, "pages": 1419, "count": 14184 } } }