Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=3&sort=-funder
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=-funder", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1424&sort=-funder", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=4&sort=-funder", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=2&sort=-funder" }, "data": [ { "type": "Grant", "id": "10685", "attributes": { "award_id": "272201700040I-0-759302200006-1", "title": "Task C14: Advancing Human Lung Microphysiological Systems to Model Coronavirus Infection and Test Candidate Countermeasures", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-09-23", "end_date": "2024-03-22", "award_amount": 1108255, "principal_investigator": { "id": 26740, "first_name": "JENNIFER", "last_name": "YOUNG", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 851, "ror": "", "name": "UNIVERSITY OF TEXAS MED BR GALVESTON", "address": "", "city": "", "state": "TX", "zip": "", "country": "United States", "approved": true }, "abstract": "This contract provides for the development and standardization of difficult-to-source reagents that require the use of nontraditional animal models of infectious diseases.", "keywords": [ "2019-nCoV", "Animal Model", "Basic Science", "COVID test", "Contracts", "Coronavirus Infections", "Development", "Human", "Lung", "Modeling", "Reagent", "Source", "Standardization", "infectious disease model", "microphysiology system" ], "approved": true } }, { "type": "Grant", "id": "10621", "attributes": { "award_id": "75N91019D00024-0-759102200021-1", "title": "NIAID / CHILDRENS NATIONAL MEDICAL CENTER JOINT CLINICAL RESEARCH PROGRAM (JCRP) IMMUNOLOGIC AND INFECTIOUS DISEASES CLINICAL RESEARCH", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-09-02", "end_date": "2026-09-01", "award_amount": 3893764, "principal_investigator": { "id": 26665, "first_name": "KEVIN", "last_name": "NEWELL", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1610, "ror": "", "name": "LEIDOS BIOMEDICAL RESEARCH, INC.", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true }, "abstract": "This is a multisite prospective observational study to evaluate the clinical sequelae of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population (aged 0-21 years), including coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C).", "keywords": [ "2019-nCoV", "COVID-19", "Child", "Childhood", "Clinical", "Clinical Research", "Communicable Diseases", "Evaluation", "Genetic", "Household", "Immune System Diseases", "Immune response", "Incidence", "Joints", "Medical", "Medical center", "Multisystem Inflammatory Syndrome in Children", "National Institute of Allergy and Infectious Disease", "Observational Study", "Outcome", "Population", "Prevalence", "Recovery", "Role", "SARS-CoV-2 infection", "Survivors", "aged", "biobank", "pediatric patients", "programs", "prospective" ], "approved": true } }, { "type": "Grant", "id": "10793", "attributes": { "award_id": "1UM2HD111076-01", "title": "Baylor College of Medicine Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-09-22", "end_date": "2029-06-30", "award_amount": 308382, "principal_investigator": { "id": 26869, "first_name": "MARY E", "last_name": "PAUL", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 849, "ror": "", "name": "WESTAT, INC.", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true }, "abstract": "Baylor College of Medicine Harris County, which includes the City of Houston, is among the 48 counties in the United States (U.S.) in which more than 50 percent of new HIV diagnoses occur. There is an urgent need for innovative and collaborative new approaches to HIV treatment and prevention in adolescents and young adults (AYA) in Houston. The long-term goal of this research is to move the U.S. and Houston area closer to ending the HIV epidemic by addressing the issues involved in successful prevention and treatment of HIV in AYA. These goals align with Adolescent Trials Network (ATN) research objectives and Houston Consortium partnerships will allow research to be conducted in AYA in all five priority areas of the ATN: improving HIV testing, preventing new infections, engaging youth in care, improving treatment and treatment effectiveness, and reducing adverse HIV health outcomes due to COVID-19. We plan to accomplish the following specific aims as a site for HIV care, research, and prevention in AYA. Aim 1 – Conduct the Trials of the ATN as identified by the ATN Executive Committee (EC) and Scientific Leadership Committee (SLC): Baylor College of Medicine (BCM) ATN site has a longstanding research unit with staff with years of experience working with AYA, both in a clinical trials settings and in the community, who are living with HIV (LWH) or are at risk for HIV. Aim 2 – Participate in the Development of Trials: BCM's ATN Project Lead and staff have years of experience in development and conducting of clinical trials in AYA and so will work in collaboration with the ATN Operations and Collaborations Center (OCC) to develop and conduct the trials performed in the ATN. In addition, the BCM Youth Community Advisory Board, (YCAB), which has had members who have been active in the ATN Youth Advisory Council (YAC) and National CAB, Youth Experts and Advocates for Health (ATN-YEAH), will evaluate and provide input on developing studies and provide and enhance ideas for future studies. Aim 3 – Provide Innovation Regarding Successful Recruitment and Enrollment of Participants: As an ATN Site Consortium, we have the structure, experience, and outreach to approach this aim at multiple levels with outreach in hard-to- reach AYA including racial and gender minority and homeless youth. Aim 4 – Provide Sites (Texas Children's Hospital and Harris Health Northwest and Thomas Street Health Center) as well as outreach within the Houston ATN Consortium, local laboratory capacity, and pharmacy support in order to conduct the ATN trials in collaboration with the OCC. Aim 5 – Continued evaluation and adjustment of Houston collaborative consortium leadership model for meaningful and continued community engagement as reflected in ATN research study participation of AYA at risk for or LWH. We anticipate the expected outcomes of improvements in each ATN priority area along the continuums of HIV infection and prevention. This project is high impact because it will provide the necessary consortium in impacted communities of AYA in a high-priority region of the U.S. to collaborate with the OCC to make sustainable progress in reaching the ATN goals.", "keywords": [ "AIDS/HIV problem", "Acquired Immunodeficiency Syndrome", "Address", "Adherence", "Adolescent Medicine Trials Network", "Adolescent and Young Adult", "Advisory Committees", "Advocate", "Affect", "African American population", "Area", "Black race", "COVID-19", "COVID-19 pandemic", "Caring", "Cities", "Clinical Trials", "Collaborations", "Communities", "Conduct Clinical Trials", "County", "Development", "Diagnosis", "Discipline of Nursing", "Drug Kinetics", "Epidemic", "Evaluation", "Failure", "Feedback", "Future", "Goals", "HIV", "HIV Infections", "HIV diagnosis", "Health", "Healthcare", "Heterosexuals", "Hispanic", "Homeless Youth", "Human Resources", "Human immunodeficiency virus test", "Individual", "Infection", "Infection prevention", "Intervention", "Intervention Studies", "Intervention Trial", "Laboratories", "Latino", "Latinx", "Lead", "Leadership", "Low income", "Medicaid", "Medical", "Medicine", "Minority Groups", "Modality", "Modeling", "Online Systems", "Outcome", "Pediatric Hospitals", "Pharmacy facility", "Prevention", "Reporting", "Research", "Risk", "Services", "Site", "Structure", "Technology", "Texas", "Treatment Effectiveness", "Uninsured", "United States", "Work", "Youth", "age group", "base", "case-based", "college", "community engagement", "design", "ethnic minority population", "experience", "gender minority youth", "health inequalities", "high risk", "human old age (65+)", "improved", "innovation", "male", "marginalized community", "meetings", "member", "motivational enhancement therapy", "novel strategies", "operation", "outreach", "participant enrollment", "pre-exposure prophylaxis", "prevent", "prevention service", "programs", "racial minority", "recruit", "research study", "sexual minority", "testing services", "transmission process", "treatment services", "uptake" ], "approved": true } }, { "type": "Grant", "id": "10833", "attributes": { "award_id": "1IK6BX006192-01", "title": "BLRD Research Career Scientist Award Application", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [], "start_date": "2023-01-01", "end_date": "2027-12-31", "award_amount": null, "principal_investigator": { "id": 22724, "first_name": "Thomas S", "last_name": "Griffith", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 764, "ror": "https://ror.org/017zqws13", "name": "University of Minnesota", "address": "", "city": "", "state": "MN", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1973, "ror": "", "name": "MINNEAPOLIS VA MEDICAL CENTER", "address": "", "city": "", "state": "MN", "zip": "", "country": "United States", "approved": true }, "abstract": "Sepsis remains the leading cause of hospital mortality today. Despite its increasing incidence due to an aging population with greater comorbidities, in-hospital mortality from sepsis has significantly declined over the past decade. This decline in mortality is due in large part to earlier recognition and better compliance with best practices in early sepsis management. Despite decreased in-hospital mortality, a large fraction (up to 50% in some studies) of sepsis survivors never fully recover and develop chronic critical illness – characterized by persistent immune suppression, recurrent infections, sepsis recidivism, and poor long-term outcomes. The applicant of this BLRD Merit Review Research Career Scientist (RCS) Award is Thomas S. Griffith, Ph.D., a Research Health Science Specialist at the Minneapolis VA Health Care System (MVAHCS) currently supported by two VA Merit Awards (I01 BX001324-10 and I01 BX001324-01). Dr. Griffith is also a Professor (with tenure) in the Department of Urology at the University of Minnesota, serving as PI on two NIH grants (1R35 GM140881-01 and 1R21 AI154527-01) and co-investigator on a third NIH grant (1R01 CA260825-01). Over the past 12 years, the applicant’s laboratory has been investigating sepsis-induced immune suppression using a combination of multiple preclinical models and human samples. Current preclinical research activities in the applicant’s laboratory leverage a novel mouse model that mimics a critical aspect of human biology – exposure to multiple ongoing and resolved infections to train the immune system for robust responses to new pathogens. Environmental pathogen exposure is one important difference between basic human and laboratory mouse biology that must be considered when using mice to evaluate immune system fitness. Humans are naturally exposed to both commensal and pathogenic microbes daily from birth, and the immune system of adult humans has been trained and shaped by each infection and vaccination experienced. While specific pathogen-free (SPF) housing of laboratory mice has been instrumental in increasing experimental reproducibility, it has simultaneously further distanced the mouse as a model from humans largely because SPF mice live their lives with limited microbial exposure. Thus, the over-arching goal of the research performed in Dr. Griffith’s laboratory is to study how changing the “starting point” of the immune system (i.e., mature, adult-like immune system of ‘dirty’ mice that have experienced physiological microbial exposure vs. naïve, neonate-like immune system of SPF mice) influences the magnitude of the acute innate immune response to a septic event. Moreover, the work being done may also help to address the important fact that there is a lack of successful treatments for humans with sepsis. Over 100 agents (many targeting cytokines) with preclinical efficacy in mouse models of sepsis have been unsuccessful in humans, making it tempting to speculate the exclusive use of SPF mice in previous preclinical studies may have underestimated the magnitude of the sepsis-induced cytokine storm and/or pathophysiology. It is expected that comparing the extent of immune dysfunction during sepsis in microbially-experienced ‘dirty’ mice to human samples will help to validate the clinical relevance of this novel mouse model that mimics this critical aspect of human biology – exposure to multiple infectious pathogens that generates an experienced immune system – to serve as an important addition to the preclinical toolbox for studying sepsis. An key component of the work performed is the expectation of making the research discoveries available to other researchers and clinicians to help inform the development and testing of new treatment options to improve the health needs of our nation’s Veterans who have experienced a septic event. It is the applicant’s goal to use this RCS award to help him put the applicant’s laboratory in the position to continue this trajectory towards clinical translation of important insights in sepsis pathophysiology gained from basic biomedical research.", "keywords": [ "Acute", "Address", "Adult", "Age", "American", "Award", "B-Lymphocytes", "Biology", "Biomedical Research", "Birth", "CD4 Positive T Lymphocytes", "Cause of Death", "Cell Compartmentation", "Cells", "Cellular Immunity", "Cessation of life", "Chronic", "Classification", "Clinical", "Clinical Research", "Clinical Treatment", "Collaborations", "Critical Illness", "Data", "Development", "Diagnosis", "Dissection", "Doctor of Philosophy", "Event", "Expenditure", "Exposure to", "Functional disorder", "Funding", "Goals", "Grant", "Growth", "Health", "Healthcare", "Healthcare Systems", "Heterogeneity", "Hospital Mortality", "Hospitalization", "Hospitals", "Housing", "Human", "Human Biology", "Immune", "Immune System Diseases", "Immune response", "Immune system", "Immunologic Adjuvants", "Immunosuppression", "Impairment", "Incidence", "Infection", "Innate Immune Response", "Inpatients", "Institution", "Intervention", "Investigation", "Iowa", "Knowledge", "Laboratories", "Laboratory mice", "Medical", "Minnesota", "Modeling", "Molecular", "Morbidity - disease rate", "Mus", "Outcome", "Paper", "Patients", "Persons", "Physiological", "Population", "Positioning Attribute", "Pre-Clinical Model", "Productivity", "Public Health", "Publications", "Publishing", "Reporting", "Reproducibility", "Research", "Research Activity", "Research Personnel", "Resources", "Sampling", "Scientist", "Sepsis", "Shapes", "Specialist", "Survivors", "T-Lymphocyte", "Testing", "Training", "Treatment Efficacy", "United States National Institutes of Health", "Universities", "Urology", "Vaccination", "Validation", "Veterans", "Vulnerable Populations", "Work", "aging population", "career", "clinical translation", "clinically relevant", "clinically significant", "commensal microbes", "comorbidity", "cytokine", "cytokine release syndrome", "emerging pathogen", "expectation", "experience", "fitness", "germ free condition", "gut microbiota", "health science research", "hospital readmission", "improved", "indexing", "insight", "memory CD4 T lymphocyte", "microbial", "mortality", "mouse model", "neonate", "novel", "pathogen", "pathogen exposure", "pathogenic microbe", "pre-clinical", "pre-clinical research", "preclinical efficacy", "preclinical study", "professor", "readmission rates", "recidivism", "recurrent infection", "response", "secondary infection", "septic", "septic patients", "success" ], "approved": true } }, { "type": "Grant", "id": "10809", "attributes": { "award_id": "1R21AG080331-01", "title": "Development and Assessment of Diagnostic Accuracy of a Telemedicine-Based Delirium Assessment Tool (The Tele-CAM)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 21701, "first_name": "Luci", "last_name": "Roberts", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-02-01", "end_date": "2025-01-31", "award_amount": 248635, "principal_investigator": { "id": 26890, "first_name": "Charles Adrian", "last_name": "Austin", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 817, "ror": "", "name": "UNIV OF NORTH CAROLINA CHAPEL HILL", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "The overarching objective of this project is to develop and establish the diagnostic accuracy of a telemedicine- based delirium assessment tool, the TELE-CAM. Delirium, an acute change in cognition and attention is associated with a variety of undesirable outcomes including increased in-hospital mortality, long-term cognitive decline that mimics dementia, and increased risk for institutionalization. Delirium is prevalent in the post-operative population, and prevalence increases with age. Recent work performed by Dr. Austin and his research team demonstrated that many subjects were discharged home with active delirium. Patients discharged with active delirium to a nursing facility have worse outcomes than non-delirious patients. Despite the known negative effects of delirium in the post-acute care institution population, little is known about the impact of persistent delirium on functional recovery after discharge to the home setting. Current clinical diagnosis of delirium requires a face-to-face encounter, which limits the ability to feasibly perform frequent delirium assessments in the post-discharge setting. Over the past few years, devices that support videoconferencing, such as smart phones, have become commonplace. Concurrently, interest in telemedicine and remote diagnoses of cognitive disorders has grown. This interest has become even more acute due to the ongoing COVID-19 pandemic. We hypothesize that currently available videoconferencing capabilities can be easily and quickly utilized to perform reliable delirium assessments in older adults in the home setting. This project will refine and assess the diagnostic accuracy of a telemedicine-based delirium assessment tool based on the CAM (the TELE-CAM) that can be utilized in the home setting and assessed by remote researchers. We propose a prospective cohort study that will develop and refine this tool as well as demonstrate the feasibility of conducting in-home delirium assessments (Aim 1). We will also establish the diagnostic accuracy of our remote delirium assessment tool compared to a reference standard face-to-face assessment (Aim 2). We will enroll 400 older participants either hospitalized for an acute medical problem or major surgery for this project. The ability to perform in-home delirium assessments will prove invaluable to researchers investigating the appropriateness of discharging actively delirious patients’ home versus keeping them in the hospital until resolution of their delirium. Further, it will provide a method for clinicians to perform quick, remote delirium assessments of their patients.", "keywords": [ "Activities of Daily Living", "Acute", "Adverse drug event", "Age", "Area Under Curve", "Assessment tool", "Attention", "Blood Vessels", "COVID-19 pandemic", "Cardiac", "Caregivers", "Cellular Phone", "Cessation of life", "Characteristics", "Clinical", "Clinical Research", "Cognition", "Cognition Disorders", "Confusion", "Delirium", "Dementia", "Detection", "Deterioration", "Development", "Devices", "Diagnostic", "Discipline of Nursing", "Early Diagnosis", "Elderly", "Enrollment", "Event", "Family", "Goals", "Home", "Home Health Aides", "Home environment", "Hospital Mortality", "Hospitalization", "Hospitals", "Impaired cognition", "Infection", "Inpatients", "Institution", "Institutionalization", "Intervention", "Interviewer", "Knowledge", "Length of Stay", "Life", "Malignant Neoplasms", "Medical", "Medicine", "Methods", "Myocardial Infarction", "Operative Surgical Procedures", "Outcome", "Participant", "Patient Discharge", "Patient-Focused Outcomes", "Patients", "Performance", "Persons", "Pharmaceutical Preparations", "Pilot Projects", "Population", "Postoperative Period", "Predictive Value", "Prevalence", "Prospective cohort study", "Recovery of Function", "Reference Standards", "Rehabilitation therapy", "Research", "Research Personnel", "Resolution", "Risk", "Sensitivity and Specificity", "Sepsis", "Skilled Nursing Facilities", "Specificity", "Stroke", "Tablet Computer", "Telemedicine", "Testing", "Time", "Videoconferencing", "Work", "acceptability and feasibility", "acute care", "austin", "base", "brain dysfunction", "clinical care", "clinical diagnosis", "cognitive testing", "confusion assessment method", "cost", "diagnostic accuracy", "diagnostic strategy", "disability", "experience", "feasibility testing", "functional decline", "heart function", "hospital readmission", "inattention", "innovation", "interest", "mortality", "mortality risk", "new technology", "remote assessment", "remote diagnosis", "statistics", "tool" ], "approved": true } }, { "type": "Grant", "id": "15995", "attributes": { "award_id": "1IK2HX003695-01A2", "title": "Improving Specialty Care Through Virtual Care Models", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [], "start_date": "2026-01-01", "end_date": "2030-12-31", "award_amount": null, "principal_investigator": { "id": 44448, "first_name": "Rebecca", "last_name": "Tisdale", "orcid": "", "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 3442, "ror": "", "name": "VETERANS ADMIN PALO ALTO HEALTH CARE SYS", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "1 Background: Specialty care deserts—the absence of specialists in geographic regions—have led to an access 2 crisis for the VA. In addition to increasing wait times and causing delays in care, these access needs drive many 3 Veterans to seek care outside VA, resulting in fragmented care, increased risks for hospitalization and hospital 4 readmission, and higher costs. In response, VA has launched the Clinical Resource Hub (CRH) program, which 5 seeks to deliver virtual care from “hub” to “spoke” sites in VA. VISN 21 has begun implementing this model in 6 cardiology at several spoke sites, but little is known about how care utilization and quality within the program. 7 Significance/Impact: This work seeks to better understand the effects of a virtual model of specialty care, in 8 this case cardiology care, on Veterans’ care access and quality. In addition, it aligns closely with several VA and 9 HSR&D priorities, chiefly access to care, virtual care/telehealth, and advancing the goals of the MISSION Act. 10 Innovation: The CRH program and the virtual care model at its core have yet to be studied in depth, and there 11 is no research in progress regarding specialty CRH despite strong interest at the national VA level in 12 understanding how specialty CRH is used and associated outcomes. Given that virtual cardiology care was very 13 limited prior to the COVID-19 pandemic, cardiology CRH is particularly novel. Hence, this project would add to 14 the limited body of research examining virtual cardiology care in the VA. In addition, the proposed work seeks to 15 evaluate this virtual care model at a time of unprecedented choice for Veterans between in-person and virtual 16 care, and limited data on how best to integrate these modalities. 17 Specific Aims: The proposed CDA will offer mentorship and training for me to pursue the following aims: 18 Aim 1. Evaluate quality of cardiology care associated with CRH implementation with administrative data. 19 I will use adjusted difference-in-difference event studies to compare cardiology quality metric achievement for 20 patients who received cardiology care via CRH versus those who received conventional VA-based cardiology care. 21 Aim 2. Assess Veteran perceptions of quality of cardiology care delivered via CRH. 22 I will interview Veterans participating in the CRH program and their caregivers regarding their experiences and 23 perceptions of quality of CRH cardiology care and elicit suggestions for key metrics to focus on for improvement. 24 Aim 3. Construct intervention to track and improve access to high-quality, equitable care through CRH. 25 Building on finding from Aims 1 and 2, I will interview clinicians and employ a facilitated deliberative process with 26 an expert advisory group to construct and pilot an intervention to improve quality. 27 Methodology: In Aim 1, I will use a difference-in-difference event study design to assess the impact of the program 28 on a battery of validated and/or guideline-based quality of cardiology care metrics. In Aim 2, guided by the Fortney 29 model of care access and quality, I will conduct semi-structured interviews of Veterans and caregivers receiving 30 care through the VISN 21 CRH program to understand their experiences with the CRH program and what outcomes 31 they recommend to include in a quality improvement intervention. In Aim 3, I will interview clinicians (Aim 3.1) and 32 conduct a facilitated deliberation process (Aim 3.2) to inform the construction of an intervention (proactive panel 33 management using a clinical dashboard tool) to track and improve quality of care and pilot the intervention. 34 Next Steps/Implementation: To continue moving this research into practice to improve health outcomes for 35 Veterans, I will extend the analysis of cardiology quality of care to compare cardiology care in the community to 36 CRH care. In addition, I will assess the effect of the intervention constructed in Aim 3 on patient outcomes and 37 clinician satisfaction via a hybrid implementation-effectiveness trial. I will continue to work with operational partners 38 to ensure cardiology CRH is improving access to high-quality cardiology care for Veterans. This project supports 39 my goal of becoming an independent VA health services researcher and leader in optimizing cardiovascular 40 disease care access, value, and equity for Veterans through virtual care innovations and implementation.", "keywords": [ "Achievement", "Address", "Area", "COVID-19 pandemic", "California", "Cardiology", "Cardiovascular Diseases", "Cardiovascular system", "Caregivers", "Caring", "Characteristics", "Cladribine", "Clinical", "Clinical Services", "Communities", "Community Health Care", "Dangerousness", "Data", "Disease", "Ensure", "Equity", "Evaluation", "Event", "Geographic Locations", "Goals", "Guidelines", "Health", "Health Services", "Health Services Accessibility", "Heart failure", "Homogeneously Staining Region", "Hospitalization", "Hospitals", "Improve Access", "Intervention", "Interview", "Medical", "Mentors", "Mentorship", "Methodology", "Methods", "Modality", "Modeling", "Morbidity - disease rate", "Nevada", "Outcome", "Pacific Islands", "Patient-Focused Outcomes", "Patients", "Perception", "Persons", "Physicians", "Policies", "Positioning Attribute", "Process", "Qualitative Methods", "Quality of Care", "Recommendation", "Research", "Research Design", "Research Personnel", "Resources", "Risk", "Rural Health", "Safety", "Site", "Specialist", "Structure", "Suggestion", "Telemedicine", "Telephone", "Testing", "Time", "Training", "Training Activity", "Veterans", "Visit", "Wait Time", "Work", "adverse outcome", "care fragmentation", "care seeking", "care utilization", "clinical implementation", "connected care", "cost", "dashboard", "design", "effectiveness/implementation trial", "experience", "follow-up", "health economics", "hospital readmission", "hospitalization rates", "implementation efforts", "implementation science", "improved", "innovation", "insight", "interest", "intervention effect", "medical specialties", "mortality", "novel", "operation", "patient subsets", "pilot test", "preference", "programs", "rapid growth", "research to practice", "response", "rural counties", "satisfaction", "sociodemographics", "southern nevada", "telehealth", "therapy design", "tool", "virtual", "virtual delivery", "virtual health care", "virtual model" ], "approved": true } }, { "type": "Grant", "id": "10881", "attributes": { "award_id": "5R01AI165947-02", "title": "Effect of natural and engineered variations on structure and biophysics of SARS-CoV-2 spike", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 26420, "first_name": "MARY KATHERINE", "last_name": "Bradford", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2022-02-01", "end_date": "2027-01-31", "award_amount": 762466, "principal_investigator": { "id": 6013, "first_name": "Priyamvada", "last_name": "Acharya", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 246, "ror": "https://ror.org/00py81415", "name": "Duke University", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 6015, "first_name": "Rory", "last_name": "Henderson", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 246, "ror": "https://ror.org/00py81415", "name": "Duke University", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "Effect of natural and engineered variations on structure and biophysics of SARS-CoV-2 spike COVID-19, caused by SARS-CoV-2, has devasted global health and economics. Vaccines are being deployed worldwide to gain control of the pandemic, although emergence of fast-spreading “variants of concern” (VOCs) have caused concern. Mutations in the spike (S) protein are under scrutiny due to its essential role in the virus life cycle, and being the dominant target of neutralizing antibodies. Widespread vaccine hesitancy and the current spread of the Delta variant provide fertile ground for emergence of vaccine- resistant variants. We and others have shown that variants use a plethora of strategies to modify antibody and receptor interactive surfaces, and spike conformation, resulting in antibody evasion and greater infectivity. Over the last two years, utilizing urgent supplement funding from the NIH, we studied the structures of SARS- CoV-2 S proteins and have established workflows spanning structure, biochemistry, biophysics and computation. Here we propose to continue the essential work of detangling the effects of variant S protein mutations, and to enhance our understanding of spike structure to further efforts to predict where the virus is heading and to inform novel vaccine designs. The scientific premise of this grant is that understanding spike structure and allostery will provide insights into its function, inform vaccine development, and provide mechanistic information essential for relating spike structure to beta-CoV replication, evolution, and immune evasion. The innovations in this grant derive from technologies we have developed for structural analyses of the S protein: an integrative structural biology pipeline combines cryo-electron microscopy (cryo-EM), Negative Stain Electron Microscopy (NSEM) and X-ray crystallography, with computational methods, and biochemical and biophysical analyses to study structural and functional properties of the spike, including furin cleavage, receptor binding, and antigenicity.", "keywords": [ "2019-nCoV", "Antibodies", "Antigens", "Biochemical", "Biochemistry", "Biological", "Biophysics", "COVID-19", "COVID-19 susceptibility", "Communication", "Computing Methodologies", "Coronavirus", "Coronavirus spike protein", "Cryoelectron Microscopy", "Data", "Data Set", "Economics", "Electron Microscopy", "Emergency Situation", "Engineering", "Evolution", "Funding", "Future", "Goals", "Grant", "Head", "Immune Evasion", "In Vitro", "Kinetics", "Life Cycle Stages", "Link", "Measures", "Methods", "Mink", "Molecular", "Molecular Conformation", "Mutagenesis", "Mutation", "Negative Staining", "Occupations", "Pathogenesis", "Peptide Hydrolases", "Peptides", "Population", "Positioning Attribute", "Predisposition", "Property", "Protein Conformation", "Proteins", "Proteolysis", "Protomer", "Recurrence", "Reporting", "Research", "Resistance", "Resolution", "Role", "SARS-CoV-2 B.1.1.7", "SARS-CoV-2 B.1.351", "SARS-CoV-2 B.1.617.2", "SARS-CoV-2 spike protein", "Site", "Structure", "Surface", "TMPRSS2 gene", "Techniques", "Technology", "United States National Institutes of Health", "Vaccine Design", "Vaccines", "Variant", "Viral", "Virus", "Work", "X-Ray Crystallography", "advanced simulation", "base", "betacoronavirus", "biophysical analysis", "combat", "computer studies", "design", "expectation", "experimental study", "global health", "in vivo", "innovation", "insight", "neutralizing antibody", "novel vaccines", "pandemic disease", "pandemic response", "protein structure", "receptor", "receptor binding", "reconstruction", "structural biology", "synergism", "vaccine development", "vaccine hesitancy", "variants of concern" ], "approved": true } }, { "type": "Grant", "id": "10605", "attributes": { "award_id": "1R01MD017521-01", "title": "Impact of Structural Racism and Discrimination on Liver Disease Disparities in High-Risk Asian American Populations", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Minority Health and Health Disparities (NIMHD)" ], "program_reference_codes": [], "program_officials": [ { "id": 8046, "first_name": "Nathaniel", "last_name": "Stinson", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2022-09-15", "end_date": "2027-05-31", "award_amount": 838349, "principal_investigator": { "id": 26647, "first_name": "GRACE X.", "last_name": "MA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1445, "ror": "", "name": "TEMPLE UNIV OF THE COMMONWEALTH", "address": "", "city": "", "state": "PA", "zip": "", "country": "United States", "approved": true }, "abstract": "Impact of Structural Racism and Discrimination on Liver Disease Disparities in High-Risk Asian American Populations Project Summary Structural racism and discrimination (SRD) play an important role in shaping persistent health disparities, including liver disease disparities among racialized Asian Americans (AAs). Despite comprising 7% of U.S. population, AAs account for more than half of all Hepatitis B (HBV) infections in the U.S. Of 2.4 million Americans infected with HBV, 58% are AAs who have the highest HBV prevalence of any racial/ethnic group. Despite CDC and U.S. Preventive Services Task Force recommendations to screen Asian adults who are at high risk for infection, a significant majority of AAs (~68-75%) have never been screened, remaining undiagnosed. SRD manifests in structural inequalities by limited access to care, culturally and linguistically appropriate services/resources, social segregation, mistrust of health system, anti-Asian racism, immigration and poverty in AAs. Most SRD research has examined how structural racism and multilevel determinants disadvantaged healthcare access for Black/African Americans and Latinx, few have included AAs. Our preliminary studies among Chinese, Korean and Vietnamese indicated that HBV screening and linkage to care disparities are attributable to the intersection of multilevel structural barriers. During COVID-19 pandemic, barriers to care for AAs are increasingly affected by anti-Asian racism, hate crimes and discrimination at each level, which impedes HBV screening and care and exacerbates liver disease disparities. The overall goal of this innovative and timely study is to identify structural racism and protective factors in relation to liver disease disparities and impact of SRD on health outcomes by Asian Americans. Guided by an adapted multilevel Socio-Ecological Model, we will leverage 20-year established Regional Cancer Health Disparities Networks to collaborate with community-based organizations and clinical partners in greater Philadelphia and NYC. Specifically, our multidisciplinary team will use mixed methods to: 1) examine the longitudinal association of individual-level SRD lived experiences (e.g., COVID-19 Anti-Asian racism, socio-historical trauma, cultural stereotype racism) and HBV screening and care among 2000 Asian Americans: Chinese, Korean and Vietnamese; 2) examine the impact of institutional-level SRD in healthcare settings (e.g., Anti-Asian racial bias, resources for patient navigators) on HBV screening uptake and care; and 3) elucidate the impact of community-level SRD (e.g., Anti-Asian racism/xenophobia and residential segregation) and protective factors (e.g. residence, social norms/advocacy and neighborhood social cohesion) on impeding or promoting screening and care. Finally, we conduct integrative analysis to examine whether individual, institutional and community-level SRD are associated with HBV screening uptake and linkage to care. This is the first multilevel, longitudinal study that will enable us to understand how structural racism drives HBV-related liver disease disparities among high-risk Asian Americans. Our study findings will identify culturally attuned strategies to mitigate SRD and design interventions to improve overall quality of chronic HBV care. Our study will likely result in a paradigm shift from individual level approach to eliminate Hepatitis B by 2030.", "keywords": [ "Adult", "Advanced Malignant Neoplasm", "Advisory Committees", "Advocacy", "Affect", "African American population", "American", "Asia", "Asian", "Asian Americans", "Black race", "COVID-19", "COVID-19 pandemic", "Caring", "Centers for Disease Control and Prevention (U.S.)", "Chinese", "Chinese American", "Chinese population", "Chronic Hepatitis B", "Clinical", "Communities", "Community Health Systems", "Community Surveys", "Crime", "Data", "Data Analyses", "Data Collection", "Death Rate", "Detection", "Development", "Diagnosis", "Disadvantaged", "Discrimination", "Ethnic group", "Federally Qualified Health Center", "Funding", "Goals", "Health", "Health Care Surveys", "Health Disparities Research", "Health Services Accessibility", "Health system", "Hepatitis", "Hepatitis B", "Hepatitis B Infection", "Hepatitis B Prevalence", "Hepatology", "Immigrant", "Immigration", "Individual", "Inequality", "Infection", "Institutional Racism", "Insurance", "Intervention", "Interview", "Koreans", "Latinx", "Linguistics", "Link", "Liver diseases", "Longitudinal Studies", "Low income", "Malignant neoplasm of liver", "Methods", "Modeling", "National Institute on Minority Health and Health Disparities", "Neighborhood Health Center", "Neighborhoods", "Not Hispanic or Latino", "Organizational Policy", "Outcome", "Patients", "Philadelphia", "Play", "Population", "Poverty", "Preventive service", "Primary Health Care", "Procedures", "Provider", "Public Health", "Quality of Care", "Recommendation", "Recording of previous events", "Regional Cancer", "Research", "Resources", "Role", "Services", "Shapes", "Stereotyping", "Structural Racism", "Surveys", "Time", "Trauma", "United States National Institutes of Health", "Work", "barrier to care", "base", "cancer diagnosis", "cancer health disparity", "community based participatory research", "density", "disease disparity", "experience", "hate crimes", "health care availability", "health care disparity", "health care settings", "health disparity", "high risk", "improved", "infection risk", "innovation", "mortality", "multidisciplinary", "perceived discrimination", "population based", "protective factors", "racial and ethnic", "racial bias", "racial disparity", "racism", "residence", "residential segregation", "resilience", "screening", "segregation", "social", "social cohesion", "social norm", "systematic review", "theories", "therapy design", "up" ], "approved": true } }, { "type": "Grant", "id": "10857", "attributes": { "award_id": "1R36HS029267-01", "title": "Patient experiences and disparities in telehealth HIV care during the COVID-19 pandemic: A mixed methods study from the Southern US", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [], "program_reference_codes": [], "program_officials": [ { "id": 26941, "first_name": "Christopher M", "last_name": "Gaines", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-01-01", "end_date": "2023-09-30", "award_amount": 41983, "principal_investigator": { "id": 26942, "first_name": "Valerie", "last_name": "Yelverton", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 930, "ror": "", "name": "UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA", "address": "", "city": "", "state": "SC", "zip": "", "country": "United States", "approved": true }, "abstract": "South Carolina (SC) is one of the priority jurisdictions for the Ending the HIV Epidemic (EHE) campaign targeting high HIV transmission areas. During the COVID-19 pandemic, SC experienced care disruptions in more than 80% of HIV clinics. To mitigate these disruptions, almost all HIV care providers offered telehealth. However, participation in and benefits from telehealth were not distributed equally. People with unstable housing, racial and ethnic minorities, older individuals, non-native English speakers, and uninsured individuals engaged in fewer telehealth encounters or experienced more challenges. Organizational, provider-, and patient-side barriers to telehealth use in HIV care included technological, digital literacy, bureaucratic, regulatory, and reimbursement issues. The extent to which COVID-19-related transitions to telehealth for HIV care should be sustained, expanded, or reversed, is not clear. This dissertation seeks to characterize patterns of and disparities in telehealth HIV care during COVID-19 and understand decision processes guiding the selection of HIV visit type. I will address 3 specific aims using a mixed methods exploratory approach: Aim 1. To assess patient and provider experiences with telehealth HIV care and telehealth-related decision processes during COVID-19. I will conduct qualitative in-depth interviews with up to 20 patients and up to 10 HIV care providers. Thematic analysis will be used to explore and synthesize constructs related to barriers, decision making, and other domains of interest. Aim 2. To characterize patterns of telehealth HIV visits during COVID-19. I will analyze electronic health record (EHR) data from approximately 2,400 adult patients cared for at Prisma’s Immunology Center (PIC) in Columbia, the largest HIV care provider in SC, to explore whether the distribution of HIV visit types varied over time and the extent to which PWH switched between in-person and telehealth visits. Aim 3. To analyze systematic variation in telehealth use in HIV care during COVID-19 with race, ethnicity, age, and rural vs. urban residence. I will analyze the same EHR data as for Aim 2 using survival and recurrent event analyses to describe systematic variation in the initiation of telehealth, reversion to in-person care, and gaps between visits, with race, ethnicity, age, and rural/urban residence. This dissertation will describe patterns of and disparities in telehealth and in-person HIV care during the COVID- 19 pandemic. Analyses of patient and provider experiences during the pandemic will inform opportunities, barriers, and challenges related to telehealth HIV care and HIV care adjustments needed to meet patient needs and used to contextualize quantitative findings of this dissertation. Equitable access to HIV care is critical for adherence and retention in care. Results of this study therefore hold great potential to inform the optimal use of telehealth, thereby contributing to EHE goals of scaling up key HIV treatment strategies and mitigate disparities in health outcomes for disadvantaged PWH.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "10873", "attributes": { "award_id": "5R34AT011547-02", "title": "Feasibility of Remote-Delivery Interventions: Tai Chi and Wellness for PTSD and Pain in Veterans", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Center for Complementary and Integrative Health (NCCIH)" ], "program_reference_codes": [], "program_officials": [ { "id": 23837, "first_name": "Lanay Marie", "last_name": "Mudd", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2022-05-10", "end_date": "2025-01-31", "award_amount": 189407, "principal_investigator": { "id": 23838, "first_name": "Deanna L.", "last_name": "Mori", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 860, "ror": "", "name": "BOSTON UNIVERSITY MEDICAL CAMPUS", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 23839, "first_name": "Barbara L.", "last_name": "Niles", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 23840, "first_name": "CHENCHEN", "last_name": "WANG", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 860, "ror": "", "name": "BOSTON UNIVERSITY MEDICAL CAMPUS", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "Posttraumatic stress disorder (PTSD) affects almost one quarter of military Veterans seeking care from Veterans Administration healthcare facilities. PTSD is associated with many health-related issues, especially chronic musculoskeletal pain, and is increasingly considered a systemic disorder, affecting both mind and body. Accessible treatments that address PTSD and chronic pain are urgently needed. Tai Chi is an ancient Chinese exercise that uses an integrated mind-body approach to enhance quality of life. Tai Chi delivered in groups has been shown to improve both mental health and physical health in patients with a variety of chronic conditions. However, no studies to date have examined Tai Chi for PTSD and pain in Veterans. Since the onset of COVID-19, interventions that can be delivered without the need for face-to-face contact are greatly needed. Remote mind-body interventions delivered via videoconferencing platforms can reduce barriers to treatment for Veterans isolated by PTSD-related avoidance, travel related challenges, or public health social distancing restrictions. The proposed study will evaluate the feasibility of remotely delivered Tai Chi for PTSD and pain in Veterans. This trial represents first steps toward a long-term goal of establishing this mind-body treatment to address these maladies for Veterans via a remote videoconferencing platform. In Phase One, the research team will adapt and do a ‘dry run’ of two existing 12-week, twice per week interventions (Tai Chi and a Wellness control) for delivery via videoconferencing for the study population. In Phase One, the team will recruit 12 participants (6 in each group) and utilize quantitative and qualitative feedback to refine and standardize the interventions. In Phase Two, 36 participants will be randomly assigned over 3 cohorts (n = 12 for each cohort, n = 6 for each group) to either a Tai Chi or a Wellness group for 12 weeks with a three-month post-treatment follow up assessment. The feasibility and acceptability of a remotely delivered randomized trial of these two interventions and the assessment protocols will be determined. Feasibility will be quantified using rates of participant eligibility, recruitment, attrition, and adherence to the treatment and assessment protocols. Feasibility will be indicated (1) by the ability to meet recruitment goals, including women and minority participation, and (2) by having at least 75% of participants regularly attend sessions and engage in home practice and 70% complete post-intervention and follow-up assessments. Acceptability will be assessed via participants’ ratings on a standardized measure of treatment satisfaction, supplemented by qualitative exit interviews. Acceptability will be indicated by 70% of the participants reporting treatment satisfaction and credibility. Information from this trial will be utilized to design a large randomized control study evaluating the efficacy of Tai Chi for improving outcomes for Veterans with PTSD and chronic musculoskeletal pain. The proposed study will be pivotal to establish procedures to fully evaluate a novel, accessible, nonpharmacologic approach for symptom management of PTSD and chronic pain in a future large-scale trial of Tai Chi.", "keywords": [ "Address", "Adherence", "Aerobic", "Affect", "Aftercare", "Boston", "COVID-19", "COVID-19 pandemic", "Cardiovascular system", "Caring", "Chinese", "Chronic", "Chronic Post Traumatic Stress Disorder", "Clinical Trials", "Data", "Development", "Diagnosis", "Disease", "Ensure", "Exercise", "Feasibility Studies", "Feedback", "Future", "Goals", "Health", "Health Services Accessibility", "Health care facility", "Healthcare Systems", "Home", "Integrative Therapy", "Intervention", "Interview", "Life", "Measures", "Memory", "Mental Health", "Mental disorders", "Military Personnel", "Mind", "Mind-Body Intervention", "Minority Participation", "Muscle", "Outcome", "Outcome Measure", "Pain", "Participant", "Patients", "Perception", "Phase", "Physical Function", "Population", "Post-Traumatic Stress Disorders", "Procedures", "Protocols documentation", "Public Health", "Quality of life", "Randomized", "Reporting", "Research", "Severities", "Social Distance", "Standardization", "Symptoms", "Tai Ji", "Trauma", "Travel", "Treatment Protocols", "United States Department of Veterans Affairs", "Veterans", "Veterans Health Administration", "Videoconferencing", "Well in self", "Woman", "acceptability and feasibility", "barrier to care", "care seeking", "chronic musculoskeletal pain", "chronic pain", "cohort", "conditioning", "cost", "design", "disability", "effective therapy", "efficacy evaluation", "eligible participant", "feasibility trial", "flexibility", "follow up assessment", "follow-up", "global health", "improved", "improved outcome", "intervention delivery", "military veteran", "novel", "participant retention", "physical conditioning", "post intervention", "post-traumatic symptoms", "psychosocial", "randomized controlled study", "randomized trial", "recruit", "remote delivery", "satisfaction", "standardize measure", "stress related disorder", "study population", "success", "symptom management" ], "approved": true } } ], "meta": { "pagination": { "page": 3, "pages": 1424, "count": 14236 } } }