Represents Grant table in the DB

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        {
            "type": "Grant",
            "id": "7282",
            "attributes": {
                "award_id": "3UH3DA044822-04S1",
                "title": "Learning from the COVID-19 pandemic to improve emergency management planning for harm reduction services in rural Ohio",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute on Drug Abuse (NIDA)"
                ],
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                    {
                        "id": 20583,
                        "first_name": "KEISHER S",
                        "last_name": "Highsmith",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
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                ],
                "start_date": "2017-08-15",
                "end_date": "2022-07-31",
                "award_amount": 138423,
                "principal_investigator": {
                    "id": 23080,
                    "first_name": "VIVIAN F.",
                    "last_name": "GO",
                    "orcid": null,
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                        {
                            "id": 778,
                            "ror": "",
                            "name": "OHIO STATE UNIVERSITY",
                            "address": "",
                            "city": "",
                            "state": "OH",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [
                    {
                        "id": 23081,
                        "first_name": "WILLIAM C",
                        "last_name": "MILLER",
                        "orcid": null,
                        "emails": "",
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                    "id": 778,
                    "ror": "",
                    "name": "OHIO STATE UNIVERSITY",
                    "address": "",
                    "city": "",
                    "state": "OH",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "COVID-19 has been devastating in many areas of the United States. Both the disease itself and the necessary mitigation measures have affected local communities. Local health departments have struggled to identify ways to continue to serve their communities. One population that has been affected in multiple ways is people who inject drugs (PWID). In many rural areas, harm reduction services have been closed because of the response to COVID-19, isolating many PWID. Some health departments have noted the absence of a clear emergency response plan to continue serving the vulnerable PWID population. Building on our relationships that we have established in our UG3/UH3 Rural Opioid Initiative project, referred to as the Ohio Opioid Project (OHOP), we will assess the impact of the COVID-19 pandemic on local stakeholders and PWID in southern Ohio. We will then use this information to develop an emergency management plan for two local health departments that provide the only syringe service programs in the area. This plan will form the basis of a generalizable approach that can be used elsewhere in rural areas of the U.S. The aims for this supplement are to: Aim 1) Explore the impact of COVID-19 on PWID and harm reduction services to identify strengths and gaps in emergency preparedness in Scioto and Gallia Counties (Step 1, PHEPARC). Aim 2) Assess the impact of COVID-19 on overdose and infectious diseases among PWID (Step 1, PHEPARC) Aim 3) Develop an emergency management plan for harm reduction and treatment services for use in Ohio and other states. In Aim 1, we will assess provider preparation, unanticipated and anticipated challenges, and the impact on services in the immediate aftermath of the pandemic. We will conduct 30 in-depth interviews with PWID and 30 in-depth interviews with substance use providers, first responders, and state and local emergency response officials. In Aim 2, we will explore PWID’s experiences with stigma, injection networks, overdose, syringe access, and access to care for MOUD and other health care through our respondent-driven sampling (RDS) survey. In Aim 3, we will draw from Aim 1 and 2 findings and work closely with the Ohio governmental agencies, local health departments, and our community advisory board to develop a flexible emergency response plan that can address the unique needs of rural counties. The plan will include a decision structure, communication plan, and detailed guidelines for substance use providers to mitigate the impact of future crises. Upon completion of this supplement, we will have a clear understanding of the impact of the COVID-19 pandemic on PWID and harm reduction support in rural Ohio. And we will provide a strategy to mitigate the impact of future crises on the rural PWID population in the future.",
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            }
        },
        {
            "type": "Grant",
            "id": "7286",
            "attributes": {
                "award_id": "3R01DA044159-02S1",
                "title": "Testing of patient-centered e-health implementation model in addiction treatment",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "NIH Office of the Director"
                ],
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                    {
                        "id": 21283,
                        "first_name": "JULIA BETH",
                        "last_name": "Zur",
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                    }
                ],
                "start_date": "2018-09-01",
                "end_date": "2023-06-30",
                "award_amount": 154983,
                "principal_investigator": {
                    "id": 10356,
                    "first_name": "DAVID H",
                    "last_name": "GUSTAFSON",
                    "orcid": null,
                    "emails": "",
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                    "approved": true,
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                        {
                            "id": 799,
                            "ror": "",
                            "name": "UNIVERSITY OF WISCONSIN-MADISON",
                            "address": "",
                            "city": "",
                            "state": "WI",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [
                    {
                        "id": 23084,
                        "first_name": "Todd David",
                        "last_name": "Molfenter",
                        "orcid": null,
                        "emails": "",
                        "private_emails": "",
                        "keywords": null,
                        "approved": true,
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                    }
                ],
                "awardee_organization": {
                    "id": 799,
                    "ror": "",
                    "name": "UNIVERSITY OF WISCONSIN-MADISON",
                    "address": "",
                    "city": "",
                    "state": "WI",
                    "zip": "",
                    "country": "United States",
                    "approved": true
                },
                "abstract": "Coronavirus (COVID-19) has disrupted the substance use disorder (SUD) treatment system, demanding an abrupt shift from in-person care to telehealth services. The transition to virtual care could permanently change SUD treatment delivery. This shift is coinciding with COVID-19-induced social isolation and anxiety, which could increase substance use and mental health disorder severity. A common refrain in the treatment and recovery field is that addiction is a disease of isolation; the cure is connection. To provide virtual treatment and the connection so essential to recovery, many SUD treatment centers are launching virtual services without a method for assessing how, where, and why virtual services are affecting their patients' quality of life and SUD recovery. The ACHESS smartphone app is currently being used at 40 Iowa treatment sites in the parent study, “Test of a patient-centered e-health intervention in addiction treatment settings.” ACHESS offers a guide and a method for assessing use of virtual services and an unprecedented research opportunity. From 3/3/20 to 3/20/20, sign-ups for ACHESS in the parent study increased by 67% compared to the two prior weeks. Activity on the ACHESS app has nearly doubled in the same period! This supplement will address patient and organizational factors because of their integral roles in providing virtual care and adopting patient-centered technologies. The supplement will enhance ACHESS with new COVID-19 related features designed to help patients comply with social distancing guidelines, cope with unprecedented social isolation, and access virtual services and supports. The research will study how patients use ACHESS features, how organizations refer patients to the ACHESS, how they interact with patients in ACHESS, and the overall impact of the ACHESS features. The supplement's research aims are: Aim 1a: Refine ACHESS to provide information, support, and data on COVID-19, social distancing, adjusting to social isolation, and how to use virtual SUD services. Then, study how patients use existing ACHESS features before (for existing ACHESS services only), during, and after the announcement of social distancing guidelines. Aim 1b: Assess how the enhanced ACHESS APP affects anxiety, loneliness, and reported COVID-19 infections. Aim 2: Create ten case studies describing how agencies implemented and used COVID-19 enhanced ACHESS and how their patients used COVID-19 enhanced ACHESS. This supplement's projected outcomes will help us understand how to design virtual recovery systems to mitigate the effects of a pandemic and the resulting social isolation. The results will help design a virtual recovery system that can be used in future emergencies and to address the on-going challenges of social isolation in society post-COVID-19.",
                "keywords": [
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                    "Alcohol or Other Drugs use",
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                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "7288",
            "attributes": {
                "award_id": "3R01MH121079-02S1",
                "title": "COVID-19 supplement to a computational examination of threat and reward constructs in a predominantly low-income, longitudinal sample at increased risk for internalizing disorders",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
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                "funder_divisions": [
                    "NIH Office of the Director"
                ],
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                    {
                        "id": 23085,
                        "first_name": "Eric Rousseau",
                        "last_name": "Murphy",
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                    }
                ],
                "start_date": "2019-08-15",
                "end_date": "2024-06-30",
                "award_amount": 155961,
                "principal_investigator": {
                    "id": 8695,
                    "first_name": "Luke Williamson",
                    "last_name": "Hyde",
                    "orcid": null,
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                        {
                            "id": 770,
                            "ror": "",
                            "name": "UNIVERSITY OF MICHIGAN AT ANN ARBOR",
                            "address": "",
                            "city": "",
                            "state": "MI",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
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                },
                "other_investigators": [
                    {
                        "id": 23086,
                        "first_name": "COLTER",
                        "last_name": "MITCHELL",
                        "orcid": null,
                        "emails": "",
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                        "keywords": null,
                        "approved": true,
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                    },
                    {
                        "id": 23087,
                        "first_name": "Christopher Stephen",
                        "last_name": "Monk",
                        "orcid": null,
                        "emails": "",
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                        "keywords": null,
                        "approved": true,
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                    "name": "UNIVERSITY OF MICHIGAN AT ANN ARBOR",
                    "address": "",
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                    "state": "MI",
                    "zip": "",
                    "country": "United States",
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                "abstract": "The novel Coronavirus (COVID-19) pandemic has had a far-reaching impact on the US population, and has disproportionately affected race-ethnic minorities, individuals living in or near poverty, and those living in large urban areas. Based on past literature we expect COVID-19 related stressors to have large negative effects on mental health, but we do not yet understand how social and economic factors might moderate those effects. The current supplement would add time-sensitive data by collecting real-time online surveys of both target young adults and their parents (n=1,200) in a representative sample of a disadvantaged population. To better understand how major stressors, like the COVID-19 pandemic, are moderated, we must assess these social, occupational, economic, health, and mental health impacts as they happen, across different cities/states (with different pandemic policies) and in those most at-risk for poor outcomes: low-income and minority families and young adults who are showing disparities in infection and mortality. Thus, by adding this critical, time-sensitive assessment, we will be even better positioned to understand how adversity shapes the ongoing development of RDoC threat and reward circuits, as well as a broader assessment of how COVID-19 is impacting mental health in marginalized, low-income, minority populations. Moreover, we will document the way in which resilience factors including social support, economic policies, and family resources moderate the negative effect of COVID-19 related stressors on mental health. This builds on the parent grant's focus to use data- driven analytics and hypothesis testing to validate multilevel-multimodal models of Threat and Reward constructs in an existing representative longitudinal cohort at risk for psychopathology and to delineate how a history of exposure to adversity links to these domains. The parent grant is assessing 600 young adults twice (at age 20 and 24) from The Fragile Families and Child Wellbeing Study (FFCWS), an ongoing study of 4900 children born 1998-200 in large US cities. Attributes of the FFCWS are: 1) parents and children were surveyed and assessed at birth, 1, 3, 5, 9, 15 years; 2) the sample is nationally representative; 3) Substantial enrichment for low-income (median income to needs ratio=1.4) and minority families (66%), populations are often under- represented in research; and 4) participants are entering early adulthood, a period of heightened risk for psychopathology. Because of the unique social distancing required by COVID-19, having data from multiple family members will be particularly powerful in understanding the economic and social, and in turn, mental health consequences of COVID-19. To predict internalizing symptoms, we will identify biotypes cross- sectionally and longitudinally. Socio-ecological conditions will be deeply assessed (including COVID-19-related adversity, prior public assistance, COVID-19 related public assistance and policies) and used to forecast the onset/intensification of internalizing symptoms at multiple units of analysis from brain to behavior to symptoms.",
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            "type": "Grant",
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                "award_id": "3R01MH121079-02S1",
                "title": "COVID-19 supplement to a computational examination of threat and reward constructs in a predominantly low-income, longitudinal sample at increased risk for internalizing disorders",
                "funder": {
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                "start_date": "2019-08-15",
                "end_date": "2024-06-30",
                "award_amount": 155961,
                "principal_investigator": {
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                    "first_name": "Luke Williamson",
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                            "state": "MI",
                            "zip": "",
                            "country": "United States",
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                        "id": 23087,
                        "first_name": "Christopher Stephen",
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                    "approved": true
                },
                "abstract": "The novel Coronavirus (COVID-19) pandemic has had a far-reaching impact on the US population, and has disproportionately affected race-ethnic minorities, individuals living in or near poverty, and those living in large urban areas. Based on past literature we expect COVID-19 related stressors to have large negative effects on mental health, but we do not yet understand how social and economic factors might moderate those effects. The current supplement would add time-sensitive data by collecting real-time online surveys of both target young adults and their parents (n=1,200) in a representative sample of a disadvantaged population. To better understand how major stressors, like the COVID-19 pandemic, are moderated, we must assess these social, occupational, economic, health, and mental health impacts as they happen, across different cities/states (with different pandemic policies) and in those most at-risk for poor outcomes: low-income and minority families and young adults who are showing disparities in infection and mortality. Thus, by adding this critical, time-sensitive assessment, we will be even better positioned to understand how adversity shapes the ongoing development of RDoC threat and reward circuits, as well as a broader assessment of how COVID-19 is impacting mental health in marginalized, low-income, minority populations. Moreover, we will document the way in which resilience factors including social support, economic policies, and family resources moderate the negative effect of COVID-19 related stressors on mental health. This builds on the parent grant's focus to use data- driven analytics and hypothesis testing to validate multilevel-multimodal models of Threat and Reward constructs in an existing representative longitudinal cohort at risk for psychopathology and to delineate how a history of exposure to adversity links to these domains. The parent grant is assessing 600 young adults twice (at age 20 and 24) from The Fragile Families and Child Wellbeing Study (FFCWS), an ongoing study of 4900 children born 1998-200 in large US cities. Attributes of the FFCWS are: 1) parents and children were surveyed and assessed at birth, 1, 3, 5, 9, 15 years; 2) the sample is nationally representative; 3) Substantial enrichment for low-income (median income to needs ratio=1.4) and minority families (66%), populations are often under- represented in research; and 4) participants are entering early adulthood, a period of heightened risk for psychopathology. Because of the unique social distancing required by COVID-19, having data from multiple family members will be particularly powerful in understanding the economic and social, and in turn, mental health consequences of COVID-19. To predict internalizing symptoms, we will identify biotypes cross- sectionally and longitudinally. Socio-ecological conditions will be deeply assessed (including COVID-19-related adversity, prior public assistance, COVID-19 related public assistance and policies) and used to forecast the onset/intensification of internalizing symptoms at multiple units of analysis from brain to behavior to symptoms.",
                "keywords": [
                    "2019-nCoV",
                    "Adult",
                    "Affect",
                    "African American",
                    "Age",
                    "Anxiety",
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                    "Birth",
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                    "Buffers",
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                    "young adult"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "10613",
            "attributes": {
                "award_id": "1U01HD110063-01",
                "title": "The longitudinal impact of the COVID-19 pandemic and related multi-level mitigation and contextual factors on health and socioeconomic outcomes of individuals and families from a vulnerable population",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "NIH Office of the Director"
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                    {
                        "id": 11129,
                        "first_name": "Rebecca L",
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                ],
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                "end_date": "2027-04-30",
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                    {
                        "id": 23087,
                        "first_name": "Christopher Stephen",
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                    },
                    {
                        "id": 26655,
                        "first_name": "Helen Carmon Spink",
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                        "keywords": null,
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                    }
                ],
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                },
                "abstract": "The COVID-19 pandemic, transmission mitigation strategies and policies implemented across the United States led to major disruption in day-to-day life, producing immediate effects on individuals, families and communities. We hypothesize that the pandemic will have broadly negative health and economic consequences, but that mitigation strategies and policies will affect participants differently in the short-, medium- and long-term based on work, family, social, and health circumstances, which can only be thoroughly examined with longitudinal analyses of data prior to and throughout the pandemic. We propose a “shovel ready” project leveraging the existing longitudinal data collected in the Fragile Families and Childhood Wellbeing Study (FFCWS), the longest running population-based US birth cohort, collected before and throughout the pandemic linked with multilevel COVID-19 related health, social and economic measures, and prospective COVID-19 impact assessments to examine these issues. FFCWS follows a representative sample of 4,898 children born 1998-2000 in large US cities and their parents over 7 waves (3,580 families participated at the last wave), providing a deep history of social support, economic factors, and health at the individual, family, neighborhood, city, and state levels. Due to the unique sampling strategy and COVID-19 transmission patterns, over 87% FFCWS families are considered underserved or COVID-19 vulnerable. Focal children are entering early adulthood, a period when major adversity may derail that transition and parents are entering middle age where the impacts of COVID-19 on health and financial resources are likely to have particularly large consequences. We will also reinterview 1,400 respondents (700 parent-adult child pairs) over two additional waves on health, economic, and behavior related to COVID-19. In collaboration with the COVID consortium, our aims are to first compare essential workers (50% of FFCWS parents and 36% of young adults), non-essential workers, and individuals who lost their jobs (over 20%) during the pandemic on short-term health, economic social and behavioral outcomes. Second, to investigate immediate and downstream effects of COVID mitigation efforts on interpersonal, intergenerational and family relationships and health resources. Third, to analyze immediate and downstream effects of COVID transmission, mitigation efforts, and COVID-related policies on health using contextual data (i.e., national, state, and local policy implementation and behavior) linked to measures of individual health in young adults and their parents collected before, and multiple times throughout the pandemic. We will also examine how these macro-level effects on individuals differ by other contextual measures such as indicators of structural racism. This project will: 1) share macro-level data on COVID-19 burden and mitigation strategies that can be linked to other studies, 2) share FFCWS COVID-19 impact survey data, 3) produce scholarly products on the short-term (2020-21), mid-term (2022-23), long-term (2024-26) effects of the COVID- 19 pandemic in a vulnerable population representative of children born in large US cities and their parents.",
                "keywords": [
                    "21 year old",
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                    "socioeconomics",
                    "transmission process",
                    "unemployment insurance",
                    "young adult"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "12018",
            "attributes": {
                "award_id": "5U01HD110063-02",
                "title": "The longitudinal impact of the COVID-19 pandemic and related multi-level mitigation and contextual factors on health and socioeconomic outcomes of individuals and families from a vulnerable population",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
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                    "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)"
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                ],
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                        "first_name": "Christopher Stephen",
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                    },
                    {
                        "id": 26655,
                        "first_name": "Helen Carmon Spink",
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                    }
                ],
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                    "approved": true
                },
                "abstract": "The COVID-19 pandemic, transmission mitigation strategies and policies implemented across the United States led to major disruption in day-to-day life, producing immediate effects on individuals, families and communities. We hypothesize that the pandemic will have broadly negative health and economic consequences, but that mitigation strategies and policies will affect participants differently in the short-, medium- and long-term based on work, family, social, and health circumstances, which can only be thoroughly examined with longitudinal analyses of data prior to and throughout the pandemic. We propose a “shovel ready” project leveraging the existing longitudinal data collected in the Fragile Families and Childhood Wellbeing Study (FFCWS), the longest running population-based US birth cohort, collected before and throughout the pandemic linked with multilevel COVID-19 related health, social and economic measures, and prospective COVID-19 impact assessments to examine these issues. FFCWS follows a representative sample of 4,898 children born 1998-2000 in large US cities and their parents over 7 waves (3,580 families participated at the last wave), providing a deep history of social support, economic factors, and health at the individual, family, neighborhood, city, and state levels. Due to the unique sampling strategy and COVID-19 transmission patterns, over 87% FFCWS families are considered underserved or COVID-19 vulnerable. Focal children are entering early adulthood, a period when major adversity may derail that transition and parents are entering middle age where the impacts of COVID-19 on health and financial resources are likely to have particularly large consequences. We will also reinterview 1,400 respondents (700 parent-adult child pairs) over two additional waves on health, economic, and behavior related to COVID-19. In collaboration with the COVID consortium, our aims are to first compare essential workers (50% of FFCWS parents and 36% of young adults), non-essential workers, and individuals who lost their jobs (over 20%) during the pandemic on short-term health, economic social and behavioral outcomes. Second, to investigate immediate and downstream effects of COVID mitigation efforts on interpersonal, intergenerational and family relationships and health resources. Third, to analyze immediate and downstream effects of COVID transmission, mitigation efforts, and COVID-related policies on health using contextual data (i.e., national, state, and local policy implementation and behavior) linked to measures of individual health in young adults and their parents collected before, and multiple times throughout the pandemic. We will also examine how these macro-level effects on individuals differ by other contextual measures such as indicators of structural racism. This project will: 1) share macro-level data on COVID-19 burden and mitigation strategies that can be linked to other studies, 2) share FFCWS COVID-19 impact survey data, 3) produce scholarly products on the short-term (2020-21), mid-term (2022-23), long-term (2024-26) effects of the COVID- 19 pandemic in a vulnerable population representative of children born in large US cities and their parents.",
                "keywords": [
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                    "transmission process",
                    "unemployment insurance",
                    "young adult"
                ],
                "approved": true
            }
        },
        {
            "type": "Grant",
            "id": "7306",
            "attributes": {
                "award_id": "3U19AI111143-06S1",
                "title": "Epidemiology of SARS-CoV-2 in Low-income Countries.",
                "funder": {
                    "id": 4,
                    "ror": "https://ror.org/01cwqze88",
                    "name": "National Institutes of Health",
                    "approved": true
                },
                "funder_divisions": [
                    "National Institute of Allergy and Infectious Diseases (NIAID)"
                ],
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                    {
                        "id": 23093,
                        "first_name": "Susana",
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                    }
                ],
                "start_date": "2020-05-21",
                "end_date": "2021-06-30",
                "award_amount": 353106,
                "principal_investigator": {
                    "id": 23094,
                    "first_name": "Michael Stephen",
                    "last_name": "Glickman",
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                        {
                            "id": 825,
                            "ror": "",
                            "name": "WEILL MEDICAL COLL OF CORNELL UNIV",
                            "address": "",
                            "city": "",
                            "state": "NY",
                            "zip": "",
                            "country": "United States",
                            "approved": true
                        }
                    ]
                },
                "other_investigators": [
                    {
                        "id": 23095,
                        "first_name": "CARL F",
                        "last_name": "NATHAN",
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                            {
                                "id": 825,
                                "ror": "",
                                "name": "WEILL MEDICAL COLL OF CORNELL UNIV",
                                "address": "",
                                "city": "",
                                "state": "NY",
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                                "country": "United States",
                                "approved": true
                            }
                        ]
                    }
                ],
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                    "id": 825,
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                    "name": "WEILL MEDICAL COLL OF CORNELL UNIV",
                    "address": "",
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                    "country": "United States",
                    "approved": true
                },
                "abstract": "The COVID-19 pandemic has now spread from high- and middle-income countries to low-income countries, including Haiti and Tanzania. The natural history of COVID-19 is unknown in low-income countries. We propose to study a combined cohort of 3,054 adults in Haiti and Tanzania to determine the attack rate of SARS-CoV-2 infection and severe COVID-19, to examine interactions with HIV infection, pulmonary tuberculosis, and hypertension in populations of African descent, and to determine long term cardiac complications of COVID-19. Cornell University has collaborated with the Groupe Haitien d’Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) in Haiti for 38 years and for 15 years with the Mwanza Intervention Trials Unit (MITU) in Tanzania. The proposed emergency supplement leverages these collaborations and four established NIH-supported cohorts, which have already been enrolled, to address NIAID priority areas. The specific aims are: 1.To determine the incidence proportion of SARS-CoV-2 infection and the attack rate and risk factors for severe COVID-19, in well characterized cohorts of 3,054 adults from low-income communities in Haiti and Tanzania. Starting May 1, 2020 we will conduct monthly telephone interviews with the 3,054 participants who are in active follow-up to record symptoms of COVID-19 during the pandemic. Participants will also be encouraged to telephone us if they develop new symptoms. We have cell phone numbers for all cohort participants and have established procedures for telephone communication. We will also review hospital records, perform verbal autopsies, and grade severity of COVID-19. We have banked sera from all participants collected in 2016-2019. In September-November 2020 and again in March-May 2021, we will collect follow-up sera and perform serologic testing for the presence of anti-SARS-CoV-2 IgG antibodies. We will determine the odds for development of severe COVID-19 in participants who had HIV, TB, and hypertension. 2. To determine the cardiac complications of SARS-CoV-2 infection in 1,909 adults with known baseline cardiac function. In 1,909 patients who previously had baseline EKGs and echocardiograms (2016-2019), we will repeat cardiac echo and EKG in 2021 to quantify the odds for development of incident left ventricular systolic dysfunction in those who did and did not become SARS-CoV-2 infected. LV function will be quantified by global longitudinal strain. We will also determine incidence of right ventricular systolic dysfunction, pulmonary hypertension and segmental wall motion abnormalities by echocardiogram, and new Q-waves and other abnormalities on EKG. Defining viral infection rates and natural history in low-income countries will be critical for future prevention interventions. Determining risk for people with HIV, TB, and hypertension will improve their care and prevention. Understanding cardiac sequelae of SARS-CoV-2 will improve care for COVID-19 survivors.",
                "keywords": [
                    "2019-nCoV",
                    "Acquired Immunodeficiency Syndrome",
                    "Address",
                    "Adult",
                    "African",
                    "Antibodies",
                    "Area",
                    "Arrhythmia",
                    "Autopsy",
                    "COVID-19",
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            "type": "Grant",
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                "award_id": "3U19AI111143-07S1",
                "title": "Epidemiology of SARS-CoV-2 in Low-income Countries.",
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                    "id": 4,
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                        "id": 23093,
                        "first_name": "Susana",
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                    "id": 23094,
                    "first_name": "Michael Stephen",
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                            "state": "NY",
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                        "first_name": "CARL F",
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                "abstract": "The COVID-19 pandemic has now spread from high- and middle-income countries to low-income countries, including Haiti and Tanzania. The natural history of COVID-19 is unknown in low-income countries. We propose to study a combined cohort of 3,054 adults in Haiti and Tanzania to determine the attack rate of SARS-CoV-2 infection and severe COVID-19, to examine interactions with HIV infection, pulmonary tuberculosis, and hypertension in populations of African descent, and to determine long term cardiac complications of COVID-19. Cornell University has collaborated with the Groupe Haitien d’Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) in Haiti for 38 years and for 15 years with the Mwanza Intervention Trials Unit (MITU) in Tanzania. The proposed emergency supplement leverages these collaborations and four established NIH-supported cohorts, which have already been enrolled, to address NIAID priority areas. The specific aims are: 1.To determine the incidence proportion of SARS-CoV-2 infection and the attack rate and risk factors for severe COVID-19, in well characterized cohorts of 3,054 adults from low-income communities in Haiti and Tanzania. Starting May 1, 2020 we will conduct monthly telephone interviews with the 3,054 participants who are in active follow-up to record symptoms of COVID-19 during the pandemic. Participants will also be encouraged to telephone us if they develop new symptoms. We have cell phone numbers for all cohort participants and have established procedures for telephone communication. We will also review hospital records, perform verbal autopsies, and grade severity of COVID-19. We have banked sera from all participants collected in 2016-2019. In September-November 2020 and again in March-May 2021, we will collect follow-up sera and perform serologic testing for the presence of anti-SARS-CoV-2 IgG antibodies. We will determine the odds for development of severe COVID-19 in participants who had HIV, TB, and hypertension. 2. To determine the cardiac complications of SARS-CoV-2 infection in 1,909 adults with known baseline cardiac function. In 1,909 patients who previously had baseline EKGs and echocardiograms (2016-2019), we will repeat cardiac echo and EKG in 2021 to quantify the odds for development of incident left ventricular systolic dysfunction in those who did and did not become SARS-CoV-2 infected. LV function will be quantified by global longitudinal strain. We will also determine incidence of right ventricular systolic dysfunction, pulmonary hypertension and segmental wall motion abnormalities by echocardiogram, and new Q-waves and other abnormalities on EKG. Defining viral infection rates and natural history in low-income countries will be critical for future prevention interventions. Determining risk for people with HIV, TB, and hypertension will improve their care and prevention. Understanding cardiac sequelae of SARS-CoV-2 will improve care for COVID-19 survivors.",
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                "award_id": "3R01DA045108-03S1",
                "title": "An adoption study of the development of early substance use: the joint roles of genetic influences, prenatal risk, rearing environment, and pubertal maturation",
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                    "id": 11921,
                    "first_name": "Leslie Diane",
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                        "id": 23096,
                        "first_name": "Jenae M.",
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