Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=1393&sort=-start_date
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=-start_date", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1424&sort=-start_date", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1394&sort=-start_date", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1392&sort=-start_date" }, "data": [ { "type": "Grant", "id": "5602", "attributes": { "award_id": "3U54MD002329-14S1", "title": "The role of prisons in community spread of COVID-19: Disparate epidemiologic profiles in rural, racial/ethnic minority, and low socioeconomic US counties", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Minority Health and Health Disparities (NIMHD)" ], "program_reference_codes": [], "program_officials": [ { "id": 19405, "first_name": "Richard", "last_name": "Berzon", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-30", "end_date": "2022-04-30", "award_amount": 179720, "principal_investigator": { "id": 19406, "first_name": "Carol Ellen", "last_name": "Cornell", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 19407, "first_name": "Carol Ellen", "last_name": "Cornell", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 772, "ror": "", "name": "UNIV OF ARKANSAS FOR MED SCIS", "address": "", "city": "", "state": "AR", "zip": "", "country": "United States", "approved": true }, "abstract": "Criminal justice (CJ) involved individuals have extremely high prevalence of risk factors associated with HIV infection including poverty, substance use, transactional sex, high numbers of sex partners, high prevalence of sexually transmitted infections and mental illness. African Americans (AA) are at disproportionate risk for both incarceration and HIV infections. A growing body of evidence highlights the efficacy of a once daily medication, emtricitabine/tenofovir, also known as pre-exposure prophylaxis (PrEP), in reducing HIV acquisition. However, structural and social barriers can undermine optimal PrEP uptake, adherence, and retention in care and must be addressed especially among those with recent CJ experience. Our proposed study is directly aligned with NIMHD Science Visioning to advance intervention approaches to improve minority health or to reduce health disparities. Our proposed study will: provide a novel exploration of facilitators and barriers to PrEP; allow us to target hard to reach populations, including MSM and substance users (both of which are top funding priority groups for the National Institutes of Health) who experience intersecting markers of HIV risk; and inform regional, and possibly national, intervention approaches to combat the overlapping epidemic of HIV and incarceration: The specific aims of the project are: Aim 1: Perform a qualitative assessment of facilitators and barriers to PrEP uptake among high-risk jail detainees, systems and interactor levels; Aim 2: Develop the PrEP-LINK intervention and perform an open label evaluation with high-risk individuals being discharged from the Pulaski County Jail; Aim 3: Conduct a pilot RCT of the PrEP-LINK intervention among high-risk men and women being released from the Pulaski County Jail. Results will inform a subsequent multi-site RCT to test efficacy of the intervention in improving PrEP uptake, adherence, and retention in care among men with CJ-experience.", "keywords": [ "Address", "Adherence", "Advocate", "African American", "Arkansas", "COVID-19", "COVID-19 disparity", "COVID-19 mortality", "COVID-19 outbreak", "COVID-19 prevention", "Caring", "Case Study", "Cessation of life", "Characteristics", "Clinical Services", "Code", "Communities", "County", "Criminal Justice", "Data", "Data Set", "Disease Outbreaks", "Ecosystem", "Epidemic", "Epidemiology", "Ethnic Origin", "Evaluation", "Foundations", "Funding", "Future", "Geographic Locations", "Goals", "HIV", "HIV Infections", "HIV risk", "Health", "Healthcare", "High Prevalence", "Imprisonment", "Incidence", "Individual", "Intervention", "Jail", "Location", "Mental disorders", "Modeling", "Morality", "Morbidity - disease rate", "New York", "Pharmaceutical Preparations", "Play", "Population", "Poverty", "Prevalence", "Prisons", "Public Health", "Quarantine", "Race", "Recommendation", "Recording of previous events", "Research", "Resources", "Risk", "Risk Factors", "Role", "Rotation", "Rural", "Rural Community", "Science", "Sexual Partners", "Sexually Transmitted Diseases", "Site", "Socioeconomic Status", "Statistical Models", "Structure", "System", "Tenofovir", "Testing", "Time", "Treatment Efficacy", "United States National Institutes of Health", "United States Public Health Service", "Woman", "Wood material", "base", "combat", "coronavirus disease", "data repository", "efficacy testing", "emtricitabine", "ethnic minority population", "evidence base", "exhaustion", "experience", "geographic population", "health disparity", "health service use", "high risk", "high risk men", "improved", "indexing", "infection rate", "low socioeconomic status", "member", "men", "men who have sex with men", "minority health", "mortality", "novel", "open label", "pandemic disease", "pre-exposure prophylaxis", "prison population", "racial and ethnic", "rural area", "rural counties", "rural underserved", "rurality", "sex", "social", "socioeconomic disparity", "socioeconomics", "substance use", "substance user", "trait", "underserved area", "underserved rural area", "uptake", "urban setting", "vision science" ], "approved": true } }, { "type": "Grant", "id": "6595", "attributes": { "award_id": "5R01HD054805-15", "title": "Childhood Risk Factors and Young Adult Competence", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)" ], "program_reference_codes": [], "program_officials": [ { "id": 22105, "first_name": "LAYLA E", "last_name": "ESPOSITO", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-30", "end_date": "2022-06-30", "award_amount": 944857, "principal_investigator": { "id": 22106, "first_name": "Jennifer E", "last_name": "Lansford", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 246, "ror": "https://ror.org/00py81415", "name": "Duke University", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "Using the most diverse, prospectively studied, multi-national sample to date, this study will generate empirical findings to develop a model of child- and family-level mediators and culture-level moderators of the role of childhood risk factors and young adult competence and maladaptation. Cross-cultural comparisons will inform domestic models of young adult maladaptation. The proposed research builds on the ongoing Parenting Across Cultures longitudinal study that began in 2008 with recruitment of a sample of 1,417 8-year-old children and their mothers and fathers from 9 countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand, and the United States). We have since assessed families annually through interviews with mothers, fathers, and children about the parent-child relationship, the child’s adjustment, attitudes and beliefs, and cultural values, with 90% retention of the original sample. During the next project period, the original child participants will be 17 to 21 years old, a crucial period for understanding family and cultural influences on decisions, risks, competencies, and opportunities. We will conduct interviews annually with young adults, their parents, and a friend to assess health-compromising and risky behaviors as well as competencies in important domains of education, work, and intimate partnerships. We address three aims: (1) We will test the hypothesis that parenting influences on impulsive risky behaviors are indeed universal, but only when the construct of “risky behaviors” is identified in a culturally specific way. We will create profiles of health-compromising and risky behaviors during the transition to adulthood that are situated in cultural contexts that vary widely with respect to economic factors, norms about the acceptability of different behaviors, and opportunities for engaging in risky behaviors. (2) We will test the hypothesis that cultural contexts moderate associations between early parenting factors and the development of both competence and maladaptation during the transition to adulthood. (3) We will use empirical findings to develop a broad model of child-level and family-level mediators of links between childhood risk factors and young-adult competence and maladaptation. Addressing these three aims in the most diverse, prospectively studied, multi-national sample to date will have major public health implications because this knowledge will inform scientific understanding of the etiology of health-compromising and risky behaviors during the transition to adulthood. This new understanding will inform intervention practices to improve population health and well-being.", "keywords": [ "21 year old", "8 year old", "Address", "Adult", "African", "Age", "Aggressive behavior", "Attitude", "Behavior", "Belief", "Child", "Child Rearing", "Childhood", "China", "Colombia", "Communication", "Competence", "Complement", "Country", "Cross-Cultural Comparison", "Development", "Discipline", "Economic Factors", "Education", "Etiology", "European", "Family", "Fathers", "Friends", "Funding", "Future", "Goals", "Health", "Hispanic Americans", "Human Development", "Impulsivity", "Informal Social Control", "International", "Intervention", "Interview", "Italy", "Jordan", "Kenya", "Knowledge", "Link", "Longitudinal Studies", "Mainstreaming", "Marriage", "Measures", "Mediating", "Mediator of activation protein", "Modeling", "Mothers", "North America", "Outcome", "Parent-Child Relations", "Parents", "Participant", "Personal Satisfaction", "Philippines", "Policies", "Population Heterogeneity", "Prevalence", "Process", "Prospective Studies", "Public Health", "Research", "Rewards", "Risk", "Risk Behaviors", "Risk Factors", "Risk-Taking", "Role", "Rome", "Sampling", "Shapes", "Sweden", "Testing", "Thailand", "Uncertainty", "United States", "Western Europe", "Work", "child bearing", "college", "computerized", "cultural values", "design", "high risk sexual behavior", "improved", "information processing", "physical abuse", "population health", "psychologic", "recruit", "sex", "social", "social skills", "substance use", "theories", "young adult" ], "approved": true } }, { "type": "Grant", "id": "7179", "attributes": { "award_id": "3R01HD054805-14S1", "title": "Childhood Risk Factors and Young Adult Competence", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 7137, "first_name": "LAYLA E", "last_name": "ESPOSITO", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-30", "end_date": "2022-06-30", "award_amount": 161000, "principal_investigator": { "id": 11773, "first_name": "Jennifer E", "last_name": "Lansford", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 246, "ror": "https://ror.org/00py81415", "name": "Duke University", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 246, "ror": "https://ror.org/00py81415", "name": "Duke University", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "Using the most diverse, prospectively studied, multi-national sample to date, this study will generate empirical findings to develop a model of child- and family-level mediators and culture-level moderators of the role of childhood risk factors and young adult competence and maladaptation. Cross-cultural comparisons will inform domestic models of young adult maladaptation. The proposed research builds on the ongoing Parenting Across Cultures longitudinal study that began in 2008 with recruitment of a sample of 1,417 8-year-old children and their mothers and fathers from 9 countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand, and the United States). We have since assessed families annually through interviews with mothers, fathers, and children about the parent-child relationship, the child’s adjustment, attitudes and beliefs, and cultural values, with 90% retention of the original sample. During the next project period, the original child participants will be 17 to 21 years old, a crucial period for understanding family and cultural influences on decisions, risks, competencies, and opportunities. We will conduct interviews annually with young adults, their parents, and a friend to assess health-compromising and risky behaviors as well as competencies in important domains of education, work, and intimate partnerships. We address three aims: (1) We will test the hypothesis that parenting influences on impulsive risky behaviors are indeed universal, but only when the construct of “risky behaviors” is identified in a culturally specific way. We will create profiles of health-compromising and risky behaviors during the transition to adulthood that are situated in cultural contexts that vary widely with respect to economic factors, norms about the acceptability of different behaviors, and opportunities for engaging in risky behaviors. (2) We will test the hypothesis that cultural contexts moderate associations between early parenting factors and the development of both competence and maladaptation during the transition to adulthood. (3) We will use empirical findings to develop a broad model of child-level and family-level mediators of links between childhood risk factors and young-adult competence and maladaptation. Addressing these three aims in the most diverse, prospectively studied, multi-national sample to date will have major public health implications because this knowledge will inform scientific understanding of the etiology of health-compromising and risky behaviors during the transition to adulthood. This new understanding will inform intervention practices to improve population health and well-being.", "keywords": [ "21 year old", "8 year old", "Address", "Administrative Supplement", "Adolescent", "Adult", "Age", "Alcohol or Other Drugs use", "Alcohols", "Anxiety", "Attitude", "Behavior", "Behavioral", "Belief", "Businesses", "COVID-19", "COVID-19 pandemic", "Child", "Child Development", "Child Rearing", "Childhood", "China", "Colombia", "Competence", "Conflict (Psychology)", "Containment", "Country", "Cross-Cultural Comparison", "Death Rate", "Development", "Economic Factors", "Economics", "Education", "Etiology", "Europe", "Family", "Fathers", "Friends", "Future", "Government", "Health", "Health system", "Human Development", "Impulsivity", "Individual", "Informal Social Control", "Institutes", "International", "Intervention", "Interview", "Italy", "Jordan", "Kenya", "Knowledge", "Lifting", "Link", "Longitudinal Studies", "Measures", "Mediator of activation protein", "Mental Depression", "Modeling", "Mothers", "Nature", "Outcome", "Parent-Child Relations", "Parents", "Participant", "Personal Satisfaction", "Philippines", "Policies", "Prospective Studies", "Public Health", "Research", "Resolution", "Rewards", "Risk", "Risk Behaviors", "Risk Factors", "Risk-Taking", "Role", "Sampling", "Shapes", "Site", "Sweden", "Testing", "Thailand", "Time", "United States", "Work", "antisocial behavior", "behavioral economics", "behavioral outcome", "behavioral response", "computerized", "cultural values", "economic outcome", "emotional functioning", "experience", "improved", "information processing", "optimism", "outcome prediction", "pandemic disease", "parent grant", "physical conditioning", "population health", "predicting response", "psychologic", "psychological outcomes", "recruit", "resilience", "response", "social", "social health determinants", "young adult" ], "approved": true } }, { "type": "Grant", "id": "5399", "attributes": { "award_id": "0748366", "title": "EPSCoR Cyberinfrastructure Assessment Workshop", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Unknown", "EPSCoR Co-Funding" ], "program_reference_codes": [], "program_officials": [], "start_date": "2007-09-15", "end_date": "2008-08-31", "award_amount": 57302, "principal_investigator": { "id": 18886, "first_name": "John W.D.", "last_name": "Connolly", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 178, "ror": "", "name": "University of Kentucky Research Foundation", "address": "", "city": "", "state": "KY", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 178, "ror": "", "name": "University of Kentucky Research Foundation", "address": "", "city": "", "state": "KY", "zip": "", "country": "United States", "approved": true }, "abstract": "This proposal for a workshop entitled \"EPSCoR Cyberinfrastructure Assessment Workshop\" was submitted July 19, 2007. To address the problem of the \"Cyberinfrastructure (CI) Gap\" between EPSCoR and non-EPSCoR jurisdictions, KY NSF EPSCoR proposes hosting a workshop that will expand on the groundwork developed at previous meetings and will ultimately result in a collaborative plan/proposal for proactively addressing CI in the EPSCoR jurisdictions. EPSCoR workshop participants will have CI expertise and performed an assessment within their respective jurisdictions to be able to present the current status of CI across the community. The first day of the workshop will consist of presentations by experts in CI from the EPSCoR jurisdictions about the capabilities and needs of the CI in their jurisdictions. Also included will be presentations by experts outside of the EPSCoR community who have set up interstate CI structures, such as networks and grids. The presentations by the outside experts will be focused on practical CI applications. The second day of the workshop will summarize the plans and extract common elements. This will lead to a coordinated plan for EPSCoR jurisdictions to share resources, e.g. a grid of computational resources with the appropriate software and expertise to make it function as a powerful scientific engine, and to provide easy access to other resources such as the NSF Teragrid.\n\nIntellectual Merit\nNSF recognizes that developing CI is inherently necessary for the nation to balance its research portfolio and to enhance the intellectual merit of future research. Cyberinfrastructure represents a changing platform for enabling the future of academic research. As this technology evolves, the EPSCoR jurisdictions run the risk of being left behind technically advanced states with robust network connections and sizable investments in high-end computing. In addition, EPSCoR jurisdictions represent diverse populations and a broad range of CI needs and conditions. The plan will position EPSCoR jurisdictions to develop the capabilities needed for future science and educational competitiveness. The results of this workshop can be carried on to the EPSCoR Annual Meeting in Hawaii where additional planning by EPSCoR jurisdiction project directors can formalize planning efforts and will ultimately result in a collaborative plan/proposal for proactively addressing CI in the EPSCoR jurisdictions.\n\nBroader Impacts\nThe broader impacts of the workshop include developing an EPSCoR-wide collaborative effort to actively address and shape the jurisdictions' response to the changing nature of academic research. This plan will necessarily include educational and training components, as there is a critical shortage of trained people in the EPSCoR jurisdictions to operate and maintain modern CI. The assessment will include CI needs for tribal and community colleges.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "5429", "attributes": { "award_id": "0727556", "title": "Biologists for the Future", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Education and Human Resources (EHR)", "S-STEM-Schlr Sci Tech Eng&Math" ], "program_reference_codes": [], "program_officials": [ { "id": 18961, "first_name": "John", "last_name": "Krupczak", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2013-08-31", "award_amount": 599545, "principal_investigator": { "id": 18964, "first_name": "Anne", "last_name": "Walter", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1406, "ror": "", "name": "Saint Olaf College", "address": "", "city": "", "state": "MN", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 18962, "first_name": "Kathy R", "last_name": "Glampe", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 18963, "first_name": "Diane", "last_name": "Angell", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 1406, "ror": "", "name": "Saint Olaf College", "address": "", "city": "", "state": "MN", "zip": "", "country": "United States", "approved": true }, "abstract": "Intellectual Merit: This project is supporting 19-20 students through a biology major as excellent preparation for meaningful scientific careers. To qualify for BFF scholarships, students must demonstrate significant financial need and show promise for success in biology. Preference is given to students from underrepresented groups. The goals are to increase the number and improve the academic outcomes of this cohort of students. The project is building on the college's interdisciplinary and research-focused biology program and its existing federally funded TRiO/Student Support Services (SSS) program. It is also building on an existing pre-matriculation biology course and Supplemental Instruction (SI) offered to all SSS students taking introductory biology. The college's Center for Experiential Learning is helping to provide career exploration and support. The Offices of Admissions and Financial Aid are helping recruit qualified students. A new initiative is an optional summer reading and writing skills course using biological literature. Other activities include optional career-oriented field trips, additional peer SI leaders and tutors, seminars and workshops, social gatherings with visiting speakers, and involvement in summer research and internships. \nBroader Impacts: The primary impact of this program is on the students themselves. The freedom to study deeply and broadly, permitted by these scholarships, helps prepare them well as biologists and gives them time to take steps to realize future careers in biology. Their impact on society will have the broadest resonance. \nThere will be impact beyond the grant period. Many of the proposed program elements will be sustained if effective (e.g., additional tutors and supplemental instruction, the proposed course). The newly identified mentors and intern hosts will continue to work with the College. The entire faculty will benefit from the scholarship of teaching activities.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "5958", "attributes": { "award_id": "3P01AG027296-13S1", "title": "Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 20399, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2024-05-31", "award_amount": 271658, "principal_investigator": { "id": 20400, "first_name": "Vincent", "last_name": "Mor", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 20401, "first_name": "AMAL N.", "last_name": "TRIVEDI", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "Major health system transformations, including the emergence of provider networks responding to Medicare’s value-based payment policies instituted under the Affordable Care Act, are poised to collide with the demography of aging and the rapid rise in the number of persons with Alzheimer’s disease and related dementias (ADRD), the majority of whom will require formal post-acute and long term care. Those with ADRD present special challenges to our current fragmented health care system, which is built upon multiple transitions across care settings and providers. Although the ADRD population is expected to triple by 2050, many recent policy changes aim to maximize the value of care for the “average” patient, without specific consideration of their consequences for high-cost, high-need populations, such as those with ADRD. This proposed Program Project, \"Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems,\" focuses on how this vulnerable population fares in the face of changing Medicare policies and the increasing use of alternative payment models. Building on two decades of research, the Brown University Center for Gerontology and Health Care Research, in conjunction with colleagues at Dartmouth College, Harvard University, University of Pennsylvania, University of Washington, and Vanderbilt University, propose to study the effects of Medicare policy changes on the care and outcomes experienced by persons with ADRD who interface with home health, skilled nursing, and long-term NH Care. The four projects and three cores all focus on the effects of national Medicare payment and quality regulation policies on the outcomes experienced by persons with ADRD. Projects vary in the populations and care settings included as well as the particular policies studied. Project 1 seeks to determine whether ADRD constitutes a disparity in access to high-quality post-acute nursing care and whether alternative payment models that incentivize greater continuity reduce this disparity, resulting in improved outcomes. Project 2 seeks to understand how ACOs’ approach to care delivery impacts the experience and outcomes of vulnerable older persons with advanced dementia. Project 3 evaluates the impact of Medicare Advantage on the outcomes for ADRD patients using home health, SNF, or end-of-life care in a nursing home. Finally, Project 4 examines the intended and unintended consequences of federal policies designed to reduce the use of antipsychotic drugs on the outcomes experienced by persons with ADRD residing in NHs, assisted living, and in the community. All projects rely upon the administrative structure provided by Core A and the methodological innovation of cross- temporal matching and the well-established linked data infrastructure provided by Core C, while Core B aims to solicit and select carefully crafted pilots of intervention studies focused on improving care for ADRD patients that may become full-scale pragmatic cluster randomized trials using extant data resources.", "keywords": [ "Acute", "Admission activity", "Affordable Care Act", "Aging", "Alzheimer&apos", "s Disease", "Alzheimer&apos", "s disease care", "Alzheimer&apos", "s disease related dementia", "Americas", "Antipsychotic Agents", "Assisted Living Facilities", "Care given by nurses", "Caring", "Catalogs", "Cluster randomized trial", "Communities", "Complex", "Conflict (Psychology)", "Disadvantaged", "Discipline of Nursing", "Disease", "Disease Progression", "Elderly", "Exposure to", "Family", "Gerontology", "Growth", "Health", "Health Care Research", "Health Policy", "Health Services", "Health system", "Healthcare", "Healthcare Systems", "Home", "Home Health Agency", "Home Nursing Care", "Hospitals", "Impaired cognition", "Incentives", "Institutes", "Interest Group", "Intervention Studies", "Link", "Literature", "Long-Term Care", "Medicaid", "Medical", "Medicare", "Medicare/Medicaid", "Methodology", "Methods", "Modeling", "Nursing Homes", "Outcome", "Paper", "Patient Discharge", "Patients", "Pennsylvania", "Persons", "Policies", "Policy Maker", "Population", "Professional Organizations", "Provider", "Public Policy", "Publishing", "Regulation", "Research", "Research Personnel", "Services", "Shapes", "Skilled Nursing Facilities", "Structure", "System", "Testing", "Treatment outcome", "Universities", "Update", "Voice", "Vulnerable Populations", "Washington", "Work", "acute care", "advanced dementia", "aging demography", "base", "bundled payment", "care delivery", "care outcomes", "college", "cost", "data infrastructure", "data management", "data resource", "design", "disparity reduction", "dual eligible", "end of life care", "experience", "federal policy", "hospital readmission", "improved", "improved outcome", "innovation", "interest", "multidisciplinary", "news", "payment", "pressure", "programs", "provider networks", "symposium", "trend", "web site" ], "approved": true } }, { "type": "Grant", "id": "5965", "attributes": { "award_id": "3P01AG027296-12S1", "title": "Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 20420, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2024-05-31", "award_amount": 270873, "principal_investigator": { "id": 20421, "first_name": "Vincent", "last_name": "Mor", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 20422, "first_name": "AMAL N.", "last_name": "TRIVEDI", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "We will illustrate how the COVID pandemic effected neuropsychiatric symptoms (NPS) and their management among nursing home (NH) residents with Alzheimer's Disease and Related Dementias (ADRD). NPS are frequent and difficult to manage under normal circumstances, and we hypothesize that COVID-prompted NH visitor restrictions and staffing reductions stimulated an increase in NPS and, consequently, in antipsychotic medication prescribing to manage NPS. The scientific premise of this proposal is that the COVID pandemic provides a unique opportunity to understand the dynamic between staffing, social isolation, NPS, and psychotropic medication use among NH residents with ADRD. The overall objective of this proposal is to measure the impact of COVID on resident behaviors and, in turn, the risk-benefit decisions to prescribe psychotropic medications in response. Our central hypothesis is that NH residents will have higher disruptions to daily care leading to more NPS and greater use of psychotropic medications during the COVID pandemic, especially within facilities with higher COVID infection rates. Our approach capitalizes on two data sources to establish trends in NPS and psychotropic use: national Minimum Data Set (MDS) assessments and electronic medical records (EMR) from a large NH chain with facilities in 30 states (Genesis Healthcare). Our aims are to: (1) evaluate changes in NPS among NH residents with ADRD during the COVID pandemic; (2) examine changes in psychotropic medication prescribing among NH residents with ADRD during the COVID pandemic; and (3) identify the proportion of NH residents with ADRD who remain long-term antipsychotic users during and post-COVID. The COVID pandemic has highlighted the tremendous needs of NH residents with ADRD. Ours will be the first large-scale investigation of factors that influence changes in NPS and psychotropic prescribing among NH residents with ADRD in the U.S. during COVID, identifying critical targets for future interventions and informing an evidence base for policy-making efforts to address future pandemics. This COVID-related supplement would extend the aims funded through Project 4 of P01AG027296, “Behavioral Control and Alzheimer's Disease: Policies, Medication Use, and Health Effects Across Care Settings.”", "keywords": [ "Address", "Aggressive behavior", "Agitation", "Alzheimer&apos", "s Disease", "Alzheimer&apos", "s disease related dementia", "Americas", "Antipsychotic Agents", "Anxiety", "Behavior", "Behavior Control", "Benefits and Risks", "Biometry", "COVID-19 pandemic", "Caring", "Cessation of life", "Communication", "Communities", "Computerized Medical Record", "Containment", "Coronavirus", "Critical Illness", "Data", "Data Set", "Data Sources", "Delirium", "Disease", "Drug Prescriptions", "Exhibits", "Family", "Friends", "Fright", "Funding", "Future", "Health", "Health Services Research", "Healthcare", "Home Nursing Care", "Intervention", "Investigation", "Knowledge", "Link", "Long-Term Care", "Measures", "Mental Depression", "Nursing Homes", "Patients", "Persons", "Pharmaceutical Preparations", "Pharmacoepidemiology", "Policies", "Policy Making", "Prevalence", "Problem behavior", "Psychoses", "Quality of life", "Quarantine", "Recommendation", "Research", "Risk", "Schedule", "Social Interaction", "Social isolation", "Symptoms", "System", "Treatment outcome", "United States", "Visit", "Work", "coronavirus disease", "evidence base", "experience", "falls", "geriatric mental health", "infection rate", "neuropsychiatric symptom", "off-label use", "pandemic disease", "reduce symptoms", "response", "stroke risk", "transmission process", "treatment strategy", "trend" ], "approved": true } }, { "type": "Grant", "id": "6200", "attributes": { "award_id": "5R01AG030611-14", "title": "LitCog IV: Health Literacy and Cognitive Function Among Older Adults", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 21021, "first_name": "JONATHAN W.", "last_name": "KING", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2025-02-28", "award_amount": 1163073, "principal_investigator": { "id": 21022, "first_name": "MICHAEL S", "last_name": "WOLF", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 924, "ror": "", "name": "NORTHWESTERN UNIVERSITY AT CHICAGO", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 924, "ror": "", "name": "NORTHWESTERN UNIVERSITY AT CHICAGO", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true }, "abstract": "We request to continue our NIA cohort study (‘LitCog’; R01AG030611). LitCog studies the confluence of increased medical morbidity resulting in complex patient self-management (SM) roles, and cognitive decline, which may affect older patients’ health literacy (HL) skills and chronic illness self-care. Functionally independent, ‘cognitively normal’ adults ages 55-74 (N=900) were recruited from community primary care practices in Chicago. Participants have completed comprehensive cognitive, psychological, social, behavioral, and functional health assessments every 3 years (4 interviews; 2008-2018). The sample is diverse by race, socioeconomic status and medical morbidity; uncommon among cognitive aging studies. A 1st renewal award (LitCog II) examined changes in cognition, HL and SM skills over 6 years and their associations with physical and mental health. We found cognitive function to be strongly associated with HL; both decline together over time. Cognitive function and HL also determine older adults’ SM skills; all predict functional health status and its decline. A 2nd renewal (LitCog III) has allowed us to capture new health behaviors, chronic disease outcomes, and healthcare use from medical, pharmacy records a decade post-baseline. Cognitive function, HL and SM skills impact all of these outcomes. LitCog III is almost complete; 774 of 900 (86%) subjects are alive and available for further study. We now propose to conduct follow-up assessments 12 and 15 years post-baseline (LitCog IV). With 6 interviews over 15 years, specific trajectories of decline in cognition, HL, SM skills and health status can be closely studied. The prevalence of and adjustment to increasing morbidity, disability, cognitive impairment (including Alzheimer’s Disease & Related Dementias (ADRD)) allow for new outcomes for investigation. Mortality data will also now be available with extended follow-up. Our primary aim is to 1) evaluate trajectories in cognitive function, HL and SM skills over 15 years among older adults, and their associations with health outcomes. LitCog is an exceptionally unique cognitive aging cohort study as it is framed in the context of health services research. Our goal has been to inform health system strategies for effectively managing older patients by understanding how cognition changes and influences HL and SM skills necessary for achieving optimal health. Modifiable factors that may mediate/moderate associations are also explored as potential intervention targets. The involvement and roles of caregivers has specifically emerged as an important social determinant of patients’ health. An administrative ADRD supplement (LitCog IIIA) has expanded our inquiry by including interviews with caregivers (informal or paid) involved in supporting the care of 60% of participants. In LitCog IV, we will create a parallel caregiver cohort, with the secondary aims to 2) investigate associations between the presence of an involved caregiver with treatment adherence, chronic disease outcomes, and functional health status among older adults; 3) identify factors influencing associations between caregiver involvement and patient outcomes.", "keywords": [ "Administrative Supplement", "Adult", "Affect", "Age", "Aging", "Alzheimer&apos", "s disease related dementia", "Award", "Behavioral", "Caregiver support", "Caregivers", "Caring", "Chicago", "Chronic", "Chronic Disease", "Cognition", "Cognitive", "Cognitive aging", "Cohort Studies", "Communities", "Complex", "Cross-Sectional Studies", "Data", "Dementia", "Disease Outcome", "Education", "Elderly", "Goals", "Health", "Health Services Research", "Health Status", "Health behavior", "Health system", "Healthcare", "Hearing", "Hospitalization", "Impaired cognition", "Intervention", "Interview", "Investigation", "Link", "Mediating", "Medical", "Mental Health", "Morbidity - disease rate", "Outcome", "Participant", "Patient-Focused Outcomes", "Patients", "Personality", "Pharmacy facility", "Positioning Attribute", "Prevalence", "Primary Health Care", "Public Health", "Race", "Records", "Risk", "Role", "Sampling", "Self Care", "Self Management", "Sensory", "Services", "Socioeconomic Status", "Technology", "Time", "Vision", "advanced disease", "base", "cognitive function", "cohort", "design", "disability", "disorder control", "follow up assessment", "follow-up", "functional decline", "health assessment", "health literacy", "medication compliance", "mortality", "multiple chronic conditions", "older patient", "patient population", "physical conditioning", "psychologic", "recruit", "skills", "social", "social determinants", "treatment adherence" ], "approved": true } }, { "type": "Grant", "id": "7295", "attributes": { "award_id": "3P01AG027296-11S1", "title": "Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 8882, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2024-05-31", "award_amount": 392129, "principal_investigator": { "id": 12729, "first_name": "Vincent", "last_name": "Mor", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "Major health system transformations, including the emergence of provider networks responding to Medicare’s value-based payment policies instituted under the Affordable Care Act, are poised to collide with the demography of aging and the rapid rise in the number of persons with Alzheimer’s disease and related dementias (ADRD), the majority of whom will require formal post-acute and long term care. Those with ADRD present special challenges to our current fragmented health care system, which is built upon multiple transitions across care settings and providers. Although the ADRD population is expected to triple by 2050, many recent policy changes aim to maximize the value of care for the “average” patient, without specific consideration of their consequences for high-cost, high-need populations, such as those with ADRD. This proposed Program Project, \"Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems,\" focuses on how this vulnerable population fares in the face of changing Medicare policies and the increasing use of alternative payment models. Building on two decades of research, the Brown University Center for Gerontology and Health Care Research, in conjunction with colleagues at Dartmouth College, Harvard University, University of Pennsylvania, University of Washington, and Vanderbilt University, propose to study the effects of Medicare policy changes on the care and outcomes experienced by persons with ADRD who interface with home health, skilled nursing, and long-term NH Care. The four projects and three cores all focus on the effects of national Medicare payment and quality regulation policies on the outcomes experienced by persons with ADRD. Projects vary in the populations and care settings included as well as the particular policies studied. Project 1 seeks to determine whether ADRD constitutes a disparity in access to high-quality post-acute nursing care and whether alternative payment models that incentivize greater continuity reduce this disparity, resulting in improved outcomes. Project 2 seeks to understand how ACOs’ approach to care delivery impacts the experience and outcomes of vulnerable older persons with advanced dementia. Project 3 evaluates the impact of Medicare Advantage on the outcomes for ADRD patients using home health, SNF, or end-of-life care in a nursing home. Finally, Project 4 examines the intended and unintended consequences of federal policies designed to reduce the use of antipsychotic drugs on the outcomes experienced by persons with ADRD residing in NHs, assisted living, and in the community. All projects rely upon the administrative structure provided by Core A and the methodological innovation of cross- temporal matching and the well-established linked data infrastructure provided by Core C, while Core B aims to solicit and select carefully crafted pilots of intervention studies focused on improving care for ADRD patients that may become full-scale pragmatic cluster randomized trials using extant data resources.", "keywords": [ "Acute", "Admission activity", "Affordable Care Act", "Aging", "Alzheimer&apos", "s Disease", "Alzheimer&apos", "s disease care", "Alzheimer&apos", "s disease related dementia", "Americas", "Antipsychotic Agents", "Assisted Living Facilities", "Care given by nurses", "Caring", "Catalogs", "Cluster randomized trial", "Communities", "Complex", "Conflict (Psychology)", "Demography", "Disadvantaged", "Discipline of Nursing", "Disease", "Disease Progression", "Elderly", "Exposure to", "Family", "Gerontology", "Growth", "Health", "Health Care Research", "Health Policy", "Health Services", "Health system", "Healthcare", "Healthcare Systems", "Home Health Agency", "Home Nursing Care", "Home environment", "Hospitals", "Impaired cognition", "Incentives", "Institutes", "Interest Group", "Intervention Studies", "Link", "Literature", "Long-Term Care", "Medicaid", "Medical", "Medicare", "Medicare/Medicaid", "Methodology", "Methods", "Modeling", "Nursing Homes", "Outcome", "Paper", "Patient Discharge", "Patients", "Pennsylvania", "Persons", "Policies", "Policy Maker", "Population", "Professional Organizations", "Provider", "Public Policy", "Publishing", "Regulation", "Research", "Research Personnel", "Services", "Shapes", "Skilled Nursing Facilities", "Structure", "System", "Testing", "Treatment outcome", "Universities", "Update", "Voice", "Vulnerable Populations", "Washington", "Work", "acute care", "advanced dementia", "base", "bundled payment", "care delivery", "care outcomes", "college", "cost", "data infrastructure", "data management", "data resource", "design", "disparity reduction", "dual eligible", "end of life care", "experience", "federal policy", "hospital readmission", "improved", "improved outcome", "innovation", "interest", "multidisciplinary", "news", "payment", "pressure", "programs", "provider networks", "symposium", "trend", "web site" ], "approved": true } }, { "type": "Grant", "id": "7296", "attributes": { "award_id": "3P01AG027296-11S2", "title": "Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 8882, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2007-09-15", "end_date": "2024-05-31", "award_amount": 184375, "principal_investigator": { "id": 12729, "first_name": "Vincent", "last_name": "Mor", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 222, "ror": "https://ror.org/05gq02987", "name": "Brown University", "address": "", "city": "", "state": "RI", "zip": "", "country": "United States", "approved": true }, "abstract": "Major health system transformations, including the emergence of provider networks responding to Medicare’s value-based payment policies instituted under the Affordable Care Act, are poised to collide with the demography of aging and the rapid rise in the number of persons with Alzheimer’s disease and related dementias (ADRD), the majority of whom will require formal post-acute and long term care. Those with ADRD present special challenges to our current fragmented health care system, which is built upon multiple transitions across care settings and providers. Although the ADRD population is expected to triple by 2050, many recent policy changes aim to maximize the value of care for the “average” patient, without specific consideration of their consequences for high-cost, high-need populations, such as those with ADRD. This proposed Program Project, \"Alzheimer's Disease and Related Disorders Treatment and Outcomes in America: Changing Policies and Systems,\" focuses on how this vulnerable population fares in the face of changing Medicare policies and the increasing use of alternative payment models. Building on two decades of research, the Brown University Center for Gerontology and Health Care Research, in conjunction with colleagues at Dartmouth College, Harvard University, University of Pennsylvania, University of Washington, and Vanderbilt University, propose to study the effects of Medicare policy changes on the care and outcomes experienced by persons with ADRD who interface with home health, skilled nursing, and long-term NH Care. The four projects and three cores all focus on the effects of national Medicare payment and quality regulation policies on the outcomes experienced by persons with ADRD. Projects vary in the populations and care settings included as well as the particular policies studied. Project 1 seeks to determine whether ADRD constitutes a disparity in access to high-quality post-acute nursing care and whether alternative payment models that incentivize greater continuity reduce this disparity, resulting in improved outcomes. Project 2 seeks to understand how ACOs’ approach to care delivery impacts the experience and outcomes of vulnerable older persons with advanced dementia. Project 3 evaluates the impact of Medicare Advantage on the outcomes for ADRD patients using home health, SNF, or end-of-life care in a nursing home. Finally, Project 4 examines the intended and unintended consequences of federal policies designed to reduce the use of antipsychotic drugs on the outcomes experienced by persons with ADRD residing in NHs, assisted living, and in the community. All projects rely upon the administrative structure provided by Core A and the methodological innovation of cross- temporal matching and the well-established linked data infrastructure provided by Core C, while Core B aims to solicit and select carefully crafted pilots of intervention studies focused on improving care for ADRD patients that may become full-scale pragmatic cluster randomized trials using extant data resources.", "keywords": [ "Acute", "Admission activity", "Affordable Care Act", "Aging", "Alzheimer&apos", "s Disease", "Alzheimer&apos", "s disease care", "Alzheimer&apos", "s disease related dementia", "Americas", "Antipsychotic Agents", "Assisted Living Facilities", "Care given by nurses", "Caring", "Catalogs", "Cluster randomized trial", "Communities", "Complex", "Conflict (Psychology)", "Demography", "Disadvantaged", "Discipline of Nursing", "Disease", "Disease Progression", "Elderly", "Exposure to", "Family", "Gerontology", "Growth", "Health", "Health Care Research", "Health Policy", "Health Services", "Health system", "Healthcare", "Healthcare Systems", "Home Health Agency", "Home Nursing Care", "Home environment", "Hospitals", "Impaired cognition", "Incentives", "Institutes", "Interest Group", "Intervention Studies", "Link", "Literature", "Long-Term Care", "Medicaid", "Medical", "Medicare", "Medicare/Medicaid", "Methodology", "Methods", "Modeling", "Nursing Homes", "Outcome", "Paper", "Patient Discharge", "Patients", "Pennsylvania", "Persons", "Policies", "Policy Maker", "Population", "Professional Organizations", "Provider", "Public Policy", "Publishing", "Regulation", "Research", "Research Personnel", "Services", "Shapes", "Skilled Nursing Facilities", "Structure", "System", "Testing", "Treatment outcome", "Universities", "Update", "Voice", "Vulnerable Populations", "Washington", "Work", "acute care", "advanced dementia", "base", "bundled payment", "care delivery", "care outcomes", "college", "cost", "data infrastructure", "data management", "data resource", "design", "disparity reduction", "dual eligible", "end of life care", "experience", "federal policy", "hospital readmission", "improved", "improved outcome", "innovation", "interest", "multidisciplinary", "news", "payment", "pressure", "programs", "provider networks", "symposium", "trend", "web site" ], "approved": true } } ], "meta": { "pagination": { "page": 1393, "pages": 1424, "count": 14236 } } }