Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=1392&sort=award_amount
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=award_amount", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1424&sort=award_amount", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1393&sort=award_amount", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1391&sort=award_amount" }, "data": [ { "type": "Grant", "id": "2690", "attributes": { "award_id": "1911375", "title": "Louis Stokes STEM Pathways and Research Alliance: Texas A&M System LSAMP-RA", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Education and Human Resources (EHR)", "Alliances-Minority Participat." ], "program_reference_codes": [], "program_officials": [ { "id": 7916, "first_name": "Leroy Jones", "last_name": "II", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2019-03-15", "end_date": "2024-02-29", "award_amount": 4000000, "principal_investigator": { "id": 7921, "first_name": "Karen", "last_name": "Butler-Purry", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 282, "ror": "", "name": "Texas A&M Engineering Experiment Station", "address": "", "city": "", "state": "TX", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 7917, "first_name": "Pamela", "last_name": "Obiomon", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 7918, "first_name": "Barbara", "last_name": "Szczerbinska", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 7919, "first_name": "Christine", "last_name": "Stanley", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 7920, "first_name": "Mahmoud T", "last_name": "Khasawneh", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 282, "ror": "", "name": "Texas A&M Engineering Experiment Station", "address": "", "city": "", "state": "TX", "zip": "", "country": "United States", "approved": true }, "abstract": "Louis Stokes STEM Pathways and Research Alliance: Texas A&M System LSAMP-RA\n\nThe Texas A&M System LSAMP Research Alliance (TAMUS LSAMP-RA) is comprised of the original members, Texas A&M University at College Station, Prairie View A&M University (a Historically Black College or University [HBCU]), and Texas A&M University-Corpus Christi (a Hispanic Serving Institution [HSI]), plus a new member, Texas A&M International University (HSI). TAMUS LSAMP-RA will 1) implement programmatic initiatives to increase engagement and enhance the success of underrepresented minority (URM) students in science, technology, engineering, and mathematics (STEM), and 2) conduct research to explore the impact of research mentoring, grit, and persistence on URM student success in STEM. A research team will investigate the impact of various factors, including the quality of research mentoring relationships on URM students' grit, persistence in STEM, and likelihood of pursuing graduate study. Research results will inform evidence-based practices in design and implementation of strong mentoring of URMs in undergraduate research. Broad dissemination of results will ensure that lessons learned and best practices will be communicated to provide URM students the information they need to succeed and to aid colleges and universities in more effectively engaging and mentoring URM students.\n\nProgrammatic initiatives will include the following: a robust academic-year undergraduate research program; international research experiences, including an introduction-to-research learning community for first-year students and a short-term team-based international research experiences for third-year students; community building and professional development activities; and a multi-pronged mentoring strategy. This project builds on a 26-year track record of success by TAMUS LSAMP, and will continue the program's role as a central resource for broadening participation across the Alliance through extensive collaborations with externally funded programs as well as with institutionalized initiatives.\n\nThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "7529", "attributes": { "award_id": "3OT2HL156812-01S3", "title": "ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating Center", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 7612, "first_name": "ANTONELLO", "last_name": "PUNTURIERI", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-06-15", "end_date": "2022-05-31", "award_amount": 4000000, "principal_investigator": { "id": 7614, "first_name": "Sonia M", "last_name": "Thomas", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 809, "ror": "", "name": "RESEARCH TRIANGLE INSTITUTE", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 809, "ror": "", "name": "RESEARCH TRIANGLE INSTITUTE", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "RTI International is pleased to provide this application as requested by the Research Opportunities Announcement OTA-20-011 ACTIV Integration of Host-targeting Therapies for COVID-19 for the role of Administrative Coordinating Center (ACC). The title of our application is ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating Center. The Integration of Host-targeting Therapies for COVID-19 Program aims to identify COVID-19 interventions relevant to heart, lung, blood, and cardiovascular outcomes that contribute to the scientific knowledge base are likely to inform clinical practice. This Program will rapidly and efficiently conduct adaptive platform trials via a coordinated effort of Data Coordinating Centers and clinical sites from existing Clinical Study Networks. The ACC is a critical component of the Program. We will coordinate with NHLBI to ensure collaboration among networks including the use of standardized approaches in clinical trial design and conduct, data collection and validation, and statistical analysis such that studies are launched, implemented and analyzed swiftly; and study findings are scientifically sound and meet regulatory needs for medical therapy development. As the ACC, we will also serve the vital role of facilitating communication and information sharing among all relevant stake holders and helping NHLBI in tracking study-specific and Program-wide milestones. Sonia Thomas, DrPH, will lead the ACC as Principal Investigator. She is an experienced CC PI and statistician with 25 years of experience in the design, implementation, and analysis of multicenter NIHand industry-sponsored Phase 2-4 clinical trials of drugs, biologics, devices, surgical and behavioral interventions in more than a dozen therapeutic indications. Dr. Thomas will be supported by Tracy Nolen, DrPH as Alternate PI, an experienced Consortium and CC PI and clinical trial statistician, and subject matter experts Steve Nissen, MD, Cleveland Clinical Chief Academic Officer, Heart and Vascular Institute, Shannon Carson, MD, Univ. of North Carolina Chief of Pulmonary and Critical Care Medicine, and Anastasia Ivanova, PhD, Univ. of North Carolina Professor of Biostatistics Under Dr Thomas’s direction, our team will lead, support, and collaborate with Program Networks through organization into 6 ACC Cores: Program Operations, Scientific Leadership and Prioritization, Informatics, Data Standards, Study Design, Implementation, & Analysis, and Regulatory and QA. We have identified milestones for the essential activities of the ACC within each of these 6 Cores with a detailed focus on the activities in the first 6 months as activities completed during this time are most important for ensuring the coordinated, expedited and efficient launch of this Program. Dr. Thomas, our subject matter experts, senior statistical scientists, and many of the core leads have substantial experience with NHLBI and thus understand the needs and priorities of the Institute and will use this knowledge to better collaborate with NHLBI and further speed up the launch of this Program. We are willing to collaborate with all involved entities as part of the overarching trans-NIH ACTIV Program as it evolves. We recognize and anticipate that swift adaptation will be required to rapidly respond to the urgent clinical research needs to address the COVID-19 pandemic. RTI is uniquely and substantially qualified for the ACC. We will use our team’s broad experience from many complex coordinating center projects to anticipate the needs for this Program and “hit the ground running”. Proven informatics technology in use by existing NIH programs will be swiftly modified by our analysts for speedy deployment of communications platforms. Our organizational size and flexibility will allow us to ramp up quickly and modify personnel resources flexibly. Lastly, RTI has a proven track record of successful collaborations with other coordinating centers on complex programs, yet as we are not directly involved with any Networks for consideration to be NHLBI COVID-19 trials sites, we provide independence and objectivity to the Program.", "keywords": [ "Address", "Adoption", "Area", "Behavior Therapy", "Biological", "Biometry", "Blood", "COVID-19", "COVID-19 pandemic", "Cardiovascular system", "Clinic", "Clinical", "Clinical Research", "Clinical Trials", "Clinical Trials Design", "Clinical Trials Network", "Collaborations", "Communication", "Complex", "Consensus", "Critical Care", "Data Collection", "Data Coordinating Center", "Development", "Devices", "Doctor of Philosophy", "Documentation", "Effectiveness", "Ensure", "Funding", "Goals", "Heart", "Human Resources", "Image", "Industry", "Informatics", "Information Dissemination", "Infrastructure", "Institutes", "International", "Intervention", "Knowledge", "Lead", "Leadership", "Lung", "Medical", "Medicine", "National Heart Lung and Blood Institute", "North Carolina", "Online Systems", "Operative Surgical Procedures", "Outcome", "Pharmaceutical Preparations", "Phase", "Principal Investigator", "Process", "Ramp", "Reporting", "Research", "Research Design", "Resources", "Role", "Running", "Scientist", "Site", "Speed", "Standardization", "Statistical Data Interpretation", "Technology", "Therapeutic", "Time", "United States National Institutes of Health", "Universities", "Validation", "clinical practice", "clinical research site", "data harmonization", "data quality", "data standards", "design", "experience", "flexibility", "informatics tool", "insight", "knowledge base", "operation", "professor", "programs", "protocol development", "sound", "targeted treatment", "therapy development" ], "approved": true } }, { "type": "Grant", "id": "10486", "attributes": { "award_id": "75N95021D00029-0-759502200002-1", "title": "SECURE PLATFORMS SUPPORT FOR THE N3C DATA ENCLAVE (COVID-19)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Center for Advancing Translational Sciences (NCATS)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-05-25", "end_date": "2022-09-24", "award_amount": 4000000, "principal_investigator": { "id": 26481, "first_name": "BRIAN", "last_name": "ZAVERTNIK", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1737, "ror": "", "name": "PALANTIR TECHNOLOGIES, INC.", "address": "", "city": "", "state": "CO", "zip": "", "country": "United States", "approved": true }, "abstract": "National COVID-19 Cohort Collaborative (N3C): The National COVID-19 Cohort Collaborative (N3C) sponsors the NIH COVID-19 Data Enclave, https://covid.cd2h.org/, one of the largest data enclaves in the world supporting COVID-19 research. N3C is a partnership among the NCATS-supported Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H), and the NIGMS-supported Institutional Development Award Networks for Clinical and Translational Research (IDeA-CTR), with overall stewardship by NCATS. The N3C Data Enclave is a secure platform storing harmonized clinical data provided by more than 60 contributing members. The Enclave hosts over 670 million clinical observations on over 6.8 million persons, including over 2.2 million COVID cases, amounting to more than 7.8 billion rows of data. To protect privacy, this data consists only of limited data sets, de-identified data sets, and synthetic data sets; there is no personally identifiable information kept in the Enclave. The Enclave resides in the NCATS Secure Scientific Platforms Environment. The Environment is a specialized cloud-based data aggregation and analytics enclave that can integrate, manage, secure, and analyze any kind of scientific data, and provide secure, controlled access to internal and external collaborators. Within the Environment, multiple NIH ICs, Federal agencies, and Federal task forces integrate, manage, secure, and analyze all types of scientific data using dedicated platforms, and, equally importantly, make that data available in specific and controlled collaborations with each other and with external collaborators.", "keywords": [ "Advisory Committees", "Award", "COVID-19", "Clinical", "Clinical Data", "Clinical Research", "Clinical and Translational Science Awards", "Collaborations", "Data", "Data Aggregation", "Data Analytics", "Data Set", "Development", "Environment", "Health", "National Center for Advancing Translational Sciences", "National Institute of General Medical Sciences", "Personally Identifiable Information", "Persons", "Privacy", "Research", "Secure", "Translational Research", "United States National Institutes of Health", "cloud based", "cohort", "coronavirus disease", "data de-identification", "data enclave", "member", "programs" ], "approved": true } }, { "type": "Grant", "id": "14749", "attributes": { "award_id": "1OT2OD037636-01", "title": "AOU WI Area of Interest 1: Community, Participant and Provider Engagement, Enrollment...", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 28291, "first_name": "IRENE", "last_name": "PRABHUDAS", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2024-01-01", "end_date": "2024-07-31", "award_amount": 4000000, "principal_investigator": { "id": 21340, "first_name": "ELIZABETH S", "last_name": "BURNSIDE", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 799, "ror": "", "name": "UNIVERSITY OF WISCONSIN-MADISON", "address": "", "city": "", "state": "WI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 31438, "first_name": "Lisa Anne", "last_name": "CadmusBertram", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31439, "first_name": "Dorothy Farrar", "last_name": "Edwards", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31440, "first_name": "Zachary", "last_name": "Franco", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31441, "first_name": "Scott Joseph", "last_name": "Hebbring", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31442, "first_name": "Todd A", "last_name": "Mahr", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31443, "first_name": "SANJAY K", "last_name": "SHUKLA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31444, "first_name": "JEFFREY C.", "last_name": "WHITTLE", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 2495, "ror": "", "name": "MARSHFIELD CLINIC RESEARCH FOUNDATION", "address": "", "city": "", "state": "WI", "zip": "", "country": "United States", "approved": true }, "abstract": "1. ABSTRACT The All of Us Research Program (AoURP) has experienced dramatic change over the last five years. To list just a few of the many examples: AoURP conducted multiple retention eligible campaigns (e.g., mental health campaign), began distributing genetic results to participants, initiated the first ancillary study (Nutrition for Precision Health), and made available the Research Workbench to scientists. Throughout the many changes that have occurred over the years, the most challenging was the SARS-Cov-2 pandemic which disrupted every facet of society and impacted how AoURP's partnering institutions functioned. But with change comes opportunity, and opportunity is possible for organizations that are highly adaptable and innovative. This includes the All of Us Wisconsin Consortium (AoU-WI). AoU-WI was one of the last RMCs to join the national program. As time progressed, AoUWI matured, strengthened close collaborations across WI and nation, and developed diverse strategies in engagement, enrollment, and retention. The diversity at all levels of AoU-WI is something we are most proud of and has allowed our program to flourish in the ever-changing AoURP. To maintain AoU-WI's momentum, we will leverage lessons learned from the last five years. AoU-WI will constantly reassess, modify, and diversify its strategies to ensure AoURP is available to all. Continued diversity in our program will be essential as AoURP persistently changes over the next five years. In this application, we will describe how AoU-WI will not only maintain successful activities that has allowed our program to be leaders in engagement, enrollment, and retention, but how we intend to innovate. We will conduct outreach and engagement activities to promote the enrollment of communities who are historically underrepresented in biomedical research (Aim 1). AoU-WI will also engage, enroll, and retain participants who reflect the rich diversity of the US (Aim 2). This will be done with both adults and pediatrics (Aim3) while ensuring participants have access to technology for study activities (Aim 4). Lastly, AoU-WI will engage and collaborate with health care providers serving communities that are historically underrepresented in biomedical research to facilitate enrollment and retention (Aim5). We will do this by expanding the AoU-WI consortium to include Advocate Aurora Health, the ninth largest not-for-profit integrated healthcare system in the U.S. By successfully achieving these aims, AoU-WI ensures our continuous contribution to the mission of \"accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.\"", "keywords": [ "Academy", "Acceleration", "Adult", "Advocacy", "Advocate", "All of Us Research Program", "American", "Ancillary Study", "Appointment", "Area", "Asian population", "Awareness", "Biomedical Research", "Black race", "COVID-19 pandemic", "Caring", "Censuses", "Childhood", "Clinic", "Collaborations", "Collection", "Communities", "Complex", "Computer Literacy", "Computers", "Consent", "Consent Forms", "Data", "Dedications", "Development", "Disease", "Education", "Electronics", "Eligibility Determination", "Enrollment", "Ensure", "Environment", "Ethics", "Ethnic Origin", "Faith", "Family", "Friends", "Frontline worker", "Genetic", "Geography", "Health", "Health Campaign", "Health Personnel", "Health system", "Healthcare", "Healthcare Systems", "Hispanic", "Hospitals", "Hour", "Household", "Indigenous", "Individual", "Infrastructure", "Inpatients", "Institution", "Institutional Review Boards", "Intake", "Integrated Health Care Systems", "Intuition", "Learning", "Letters", "Life Style", "Link", "Location", "Measurement", "Medical", "Mental Health", "Minority Groups", "Mission", "Modeling", "Mothers", "Native American population", "Newborn Infant", "Older Population", "Outpatients", "Paper", "Parents", "Participant", "Pediatric Hospitals", "Pediatrics", "Pharmacy facility", "Population", "Population Heterogeneity", "Positioning Attribute", "Precision Health", "Process", "Productivity", "Provider", "Recontacts", "Refugees", "Research", "Research Personnel", "Research Training", "Rural", "Rural Population", "Scientist", "Site", "Social Work", "Societies", "Source", "Southeastern Asia", "Special Population", "Surveys", "Technology", "Time", "United States", "United States National Institutes of Health", "Universities", "Urban Community", "Vietnam", "Visit", "Walking", "War", "Wisconsin", "Youth", "biobank", "care delivery", "care providers", "career", "community center", "community partners", "demographics", "disability", "ethnic diversity", "experience", "flexibility", "follow-up", "health care service organization", "human disease", "illiteracy", "individualized prevention", "innovation", "interest", "literacy", "medical schools", "meetings", "member", "migration", "outreach", "pandemic disease", "participant enrollment", "participant retention", "pediatrician", "precision medicine", "precision nutrition", "programs", "racial diversity", "recruit", "retention rate", "retiree", "rural area", "social", "success" ], "approved": true } }, { "type": "Grant", "id": "11980", "attributes": { "award_id": "2120746", "title": "Engineering for US All-E4USA: A National Pilot High School Engineering Course and Database", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Engineering (ENG)", "EWFD-Eng Workforce Development" ], "program_reference_codes": [], "program_officials": [ { "id": 27155, "first_name": "Patricia", "last_name": "Simmons", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2021-10-01", "end_date": "2024-09-30", "award_amount": 4007357, "principal_investigator": { "id": 11502, "first_name": "Darryll", "last_name": "Pines", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 297, "ror": "https://ror.org/047s2c258", "name": "University of Maryland, College Park", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 11499, "first_name": "Stacy S", "last_name": "Klein-Gardner", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 11500, "first_name": "Kenneth J", "last_name": "Reid", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 11501, "first_name": "Adam R", "last_name": "Carberry", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 27864, "first_name": "Carl", "last_name": "White", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 297, "ror": "https://ror.org/047s2c258", "name": "University of Maryland, College Park", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true }, "abstract": "The aim of the Engineering for US All (e4usa): A National Pilot Program for High School Engineering Course and Database project is to demystify and democratize engineering through a program targeting high school students and teachers that will by nature benefit society and advance the desire for a more diverse future engineering workforce. The program expands the pool of teachers capable of teaching engineering and the number of students considering further education and/or a career in engineering. The knowledge taught by empowered teachers will provide a broader understanding of engineering intended to excite an interest in pursuing additional engineering education. Specific efforts to collaborate with a diverse group of schools (urban, suburban, rural, private, public, parochial, single gender, etc.) will ensure that this program reaches those who have previously been unable to offer engineering and/or traditionally underrepresented in engineering. Partnerships with post-secondary institutions will also create and facilitate pathways for students to explore possible engineering careers. Scaling and sustaining e4usa will allow the project to address the desired societal outcome of a more educated citizenry and increased numbers and diversity of students joining the future engineering workforce. Continued support for e4usa will establish the program as major contributor in the field of engineering and technological literacy, while bringing engineering truly to all.\n\nEngineering for US All (e4usa): A National Pilot Program for High School Engineering Course and Database’s primary goal is to demystify and democratize the learning and practice of engineering by engaging high school students and teachers in a project-based engineering curriculum. e4usa will increase engineering literacy for all and expand opportunities for those traditionally underserved and underrepresented in engineering to pursue careers as engineers. Current NSF funding has led to the creation of the e4usa curriculum, teacher professional learning (e.g., professional development workshops and community of practice), and additional supporting resources (e.g., MyDesign®). This first of its kind program presents the engineering field using four big ideas: 1) discover engineering, 2) engineering in society, 3) engineering professional skills, and 4) engineering design. This Design and Development grant is intended to support efforts to scale, study, and sustain e4usa over the next three years. School settings will be broadened by expanding the reach of e4usa to 50 teachers and approximately 5,000 students nationwide. Design-Based Implementation Research (DBIR) capturing participating student and teacher data will continue and expand to include five in-depth case studies. Knowledge gained will inform central components of e4usa intended to improve developed resources, expand partnerships, garner insights into the impacts of e4usa, and increase pathways for credit and placement These insights, in conjunction with the creation of an oversight and advocacy agency, will provide the foundation for e4usa becoming a self-sustaining, independent entity supported by key partners like TeachEngineering.\n\nThis award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "9304", "attributes": { "award_id": "75N93020C00052-P00001-9999-1", "title": "Development of a COVID-19 Vaccine", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2020-09-01", "end_date": "2023-02-05", "award_amount": 4015904, "principal_investigator": { "id": 25044, "first_name": "STEVEN", "last_name": "REED", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1031, "ror": "", "name": "HDT BIO CORPORATION", "address": "", "city": "", "state": "WA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1031, "ror": "", "name": "HDT BIO CORPORATION", "address": "", "city": "", "state": "WA", "zip": "", "country": "United States", "approved": true }, "abstract": "To support the advanced development of candidate products for use following the intentional release of or in response to naturally occurring outbreaks of infectious diseases caused by NIAID Category A, B, and C Priority Pathogens or emerging infectious diseases. This contract may support formulation and manufacture of the individual vaccine components, as well as stability testing, nonclinical immunogenicity and efficacy testing in animal models, IND enabling GLP toxicology, submission of an IND and clinical safety and efficacy evaluation.", "keywords": [ "Advanced Development", "Animal Model", "COVID-19 vaccine", "Categories", "Clinical", "Communicable Diseases", "Contracts", "Development", "Disease Outbreaks", "Emerging Communicable Diseases", "Formulation", "Individual", "National Institute of Allergy and Infectious Disease", "Safety", "Toxicology", "Vaccines", "efficacy evaluation", "efficacy testing", "immunogenicity", "priority pathogen", "response", "stability testing", "vaccine development" ], "approved": true } }, { "type": "Grant", "id": "6678", "attributes": { "award_id": "1U19AI171401-01", "title": "Medicinal Chemistry Core", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2022-05-16", "end_date": "2025-04-30", "award_amount": 4033569, "principal_investigator": { "id": 22358, "first_name": "JAMES M", "last_name": "BALKOVEC", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1487, "ror": "https://ror.org/008zj0x80", "name": "Hackensack University Medical Center", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1487, "ror": "https://ror.org/008zj0x80", "name": "Hackensack University Medical Center", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true }, "abstract": "The Medicinal Chemistry Core (MCC; Core 4) has been formed to address the urgent need for novel antiviral agents. The MCC will work seamlessly with the Project Teams and other Cores to drive the time- and cost- efficient discovery and development of novel optimized lead compounds to target viral infections of global health significance. Critical to its mission is its competence in industrial and academic medicinal chemistry, which is highlighted by successful evolutions of hit to lead to approved drug. The MCC will aid in the confirmation of hits discovered through structure-based design or experimental screens, evolve these to early and then optimized leads following a defined workflow with quantitative metrics for molecules at each stage in the process. The MCC will collaborate on projects focused on the discovery and development of 1) inhibitors of SARS-CoV-2 RNA dependent RNA polymerase (RdRp) (Nsp12/7/8) and exonuclease (ExoN) (Nsp14/10), 2) viral protease inhibitors from a high-throughput yeast-based screen, and 3) syn-BNP peptides as antiviral agents.", "keywords": [ "Address", "Antiviral Agents", "Biological", "Biological Assay", "Biological Availability", "Biotechnology", "COVID-19 pandemic", "COVID-19 therapeutics", "Chemicals", "Competence", "Complement", "Cryoelectron Microscopy", "Crystallography", "Data", "Development", "Docking", "Drug Interactions", "Drug Kinetics", "Drug toxicity", "Ensure", "Evaluation", "Evolution", "Exonuclease", "Generations", "Goals", "Human", "In Vitro", "Industrialization", "Industry", "Lead", "Leadership", "Libraries", "Logistics", "Mammalian Cell", "Mission", "Modeling", "Molecular", "Oral", "Peptides", "Pharmaceutical Chemistry", "Pharmaceutical Preparations", "Pharmacologic Substance", "Postdoctoral Fellow", "Process", "Property", "Protease Inhibitor", "RNA-Directed RNA Polymerase", "Research Personnel", "SARS-CoV-2 inhibitor", "Series", "Source", "Structure", "Structure-Activity Relationship", "Synthesis Chemistry", "Time", "Toxic effect", "Translations", "Validation", "Viral", "Virus", "Virus Diseases", "Vision", "Work", "Yeasts", "analog", "anti-viral efficacy", "base", "cheminformatics", "cost efficient", "cytotoxicity", "design", "drug candidate", "drug development", "drug discovery", "experience", "follow-up", "global health", "improved", "in vivo", "insight", "lead optimization", "metropolitan", "novel", "novel therapeutics", "pandemic disease", "programs", "screening", "small molecule", "translational potential" ], "approved": true } }, { "type": "Grant", "id": "10998", "attributes": { "award_id": "3G20AI167408-01S1", "title": "Administrative Supplements for NIAID Regional Biocontainment Laboratories (RBL)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 24445, "first_name": "Nancy G.", "last_name": "Boyd", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2021-09-23", "end_date": "2024-02-29", "award_amount": 4039853, "principal_investigator": { "id": 24446, "first_name": "Farhang", "last_name": "Alem", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 239, "ror": "https://ror.org/02jqj7156", "name": "George Mason University", "address": "", "city": "", "state": "VA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 239, "ror": "https://ror.org/02jqj7156", "name": "George Mason University", "address": "", "city": "", "state": "VA", "zip": "", "country": "United States", "approved": true }, "abstract": "Project Summary/Abstract: The ongoing COVID pandemic has demonstrated the need for state-of-the-art facilities and infrastructure to improve our preparedness for subsequent epidemics and/or pandemics. George Mason University (GMU), leveraging the Regional Biocontainment Laboratory, designated as the Biomedical Research Laboratory (BRL), has established a biomedical research program with a strong emphasis on newly emerging and re- emerging viral and bacterial pathogens with the potential to cause severe human and animal diseases. The specific viral pathogen families of greatest pandemic concern currently investigated in the BRL are: Togaviridae, Bunyaviridae, Coronaviridae, and Flaviviridae. Several faculty members in five departments at GMU (Systems Biology, Biology, Bioengineering, Biochemistry, and Global and Community Health) as well as external collaborators conduct research on basic and applied research to include pathogenicity, infection mechanisms, and development of diagnostics, vaccines and therapeutics. The infectious disease portfolio at GMU was $8.8 million in FY21 and is expected to grow by at least 3X in the next five years. To realize this goal, GMU leadership is making aggressive, strategic investments in new faculty hires and seed funding, as well as creating broader access to the BRL. More than 244 peer-reviewed articles on infectious diseases research have been published by GMU investigators since 2010. The BRL staff is dedicated to supporting GMU faculty, students, and their collaborators to develop new translational solutions for pandemic preparedness. Research with translational promise includes 1) development of additional vaccine candidates that confer broad-spectrum protection against multiple strains of alphaviruses or coronaviruses, 2) evaluation of host-based therapeutics that have demonstrated in vitro broad- spectrum efficacy against alphaviruses (VEEV, EEEV, WEEV, CHIKV), bunyaviruses (RVFV) and coronaviruses (SARS-CoV-2) in rodent and nonrodent animal models including ferrets, and 3) development of new platform technologies including extracellular vesicle (EV)-based immunomodulators and reporter viruses that can facilitate rapid screening of clinical and nonclinical samples for neutralizing antibodies. Our high containment facility supported by a team of operations and technical staff, creates opportunities for a broad base of internal and external investigators to conduct in vitro and in vivo research and development on newly emerging and re-emerging viral and bacterial pathogens. GMU is requesting funds to supplement the funded G20 parent award, “Facility and Building System Upgrades Support for the Mason Biomedical Research Laboratory” to resolve additional specific instrumentation and facility gaps that will support the creation of a modern, comprehensive, agile and resilient preclinical biomedical research pipeline to address national and global pandemic preparedness.", "keywords": [ "2019-nCoV", "Address", "Administrative Supplement", "Alphavirus", "Animal Diseases", "Animal Model", "Animals", "Applied Research", "Award", "Basic Science", "Biochemistry", "Biological Assay", "Biology", "Biomedical Engineering", "Biomedical Research", "Bunyaviridae", "COVID-19 pandemic", "Cells", "Chikungunya virus", "Clinical", "Collaborations", "Communicable Diseases", "Community Health", "Containment", "Core Facility", "Coronavirus", "Development", "Diagnostic", "Ensure", "Epidemic", "Evaluation", "FDA approved", "Faculty", "Family", "Ferrets", "Flaviviridae", "Funding", "Goals", "Government", "Histology", "Image", "Immunomodulators", "In Vitro", "Infection", "Infectious Diseases Research", "Infrastructure", "Investments", "Laboratories", "Laboratory Research", "Leadership", "Methodology", "Modernization", "Molecular", "National Institute of Allergy and Infectious Disease", "Orthobunyavirus", "PET/CT scan", "Parents", "Pathogenesis", "Pathogenicity", "Peer Review", "Pharmaceutical Preparations", "Population", "Publishing", "Rapid screening", "Readiness", "Reagent", "Reporter", "Research", "Research Personnel", "Rodent", "Sampling", "Security", "Seeds", "Sterilization", "Students", "System", "Systems Analysis", "Systems Biology", "Talents", "Technology", "Therapeutic", "Togaviridae", "Universities", "Vaccines", "Venezuelan Equine Encephalitis Virus", "Virus", "Water", "Western Equine Encephalitis Virus", "advanced system", "animal imaging", "animal tissue", "arm", "base", "cellular imaging", "combat", "extracellular vesicles", "global health", "human disease", "imager", "improved", "in vivo", "industry partner", "innovation", "instrument", "instrumentation", "member", "multiple omics", "neutralizing antibody", "novel", "operation", "pandemic disease", "pandemic preparedness", "particle", "pathogenic bacteria", "pathogenic virus", "pre-clinical", "programs", "recruit", "research and development", "sequencing platform", "small molecule", "technology development", "therapeutic candidate", "therapeutic development", "tissue processing", "transcriptomics", "vaccine candidate", "vaccine development" ], "approved": true } }, { "type": "Grant", "id": "14422", "attributes": { "award_id": "2043250", "title": "CyberCorps Scholarship for Service (Renewal): Advancing a Successful Cybersecurity Education and Workforce Development Program", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Directorate for STEM Education (EDU)", "CYBERCORPS: SCHLAR FOR SER" ], "program_reference_codes": [], "program_officials": [ { "id": 9732, "first_name": "Li", "last_name": "Yang", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2021-08-01", "end_date": null, "award_amount": 4049354, "principal_investigator": { "id": 31039, "first_name": "Luc", "last_name": "Longpre", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 31039, "first_name": "Luc", "last_name": "Longpre", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31040, "first_name": "Monika", "last_name": "Akbar", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31041, "first_name": "Christopher D", "last_name": "Kiekintveld", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 31042, "first_name": "Saeid", "last_name": "Tizpaz-Niari", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 446, "ror": "", "name": "University of Texas at El Paso", "address": "", "city": "", "state": "TX", "zip": "", "country": "United States", "approved": true }, "abstract": "The central role of software in the operation of defense, energy, communication, transportation, and manufacturing systems makes it increasingly important that these systems are designed in a way that integrates cybersecurity principles. The renewal of the CyberCorps® Scholarship for Service (SFS) program at the University of Texas at El Paso (UTEP) will continue the support of highly qualified students, in particular Latinx and female students, who complete a cybersecurity-focused program and graduate with the ability to apply disciplined software development principles and processes. UTEP is uniquely positioned to contribute to efforts to improve diversity in the cybersecurity workforce due to the population it serves, which includes Hispanic, first generation, and lowest income quartile students. UTEP students do not fit the “traditional” student profile of a full-time student transitioning directly from high school to a four-year college or university as many students transfer from local community colleges and pursue their education part-time. Over the past five years, UTEP has made significant advances in developing cybersecurity educational programs, research, and outreach activities at UTEP and beyond. These efforts have resulted in recognitions including the National Security Agency designation as a Center of Academic Excellence in both Cyber Defense and Cyber Operations (only one of 21 across the nation), as well as the designation as an Army Research Lab-South remote campus in cybersecurity.<br/><br/>UTEP’s SFS Scholars complete rigorous educational programs with a focus on cybersecurity and complement the knowledge gained in the classroom through significant involvement in cybersecurity research, training, competitions, and hands-on activities. All UTEP SFS Scholars are also required to engage in service to the community to build cybersecurity awareness and capabilities among UTEP students and beyond. The goals of the UTEP SFS program are to 1) recruit and retain at least 30 students into UTEP’s Master of Science in Software Engineering and the doctoral computer science programs; 2) graduate students who will enter the workforce with the ability to transfer state-of-the-art cybersecurity techniques and approaches into practice; 3) place students in government positions that utilize their knowledge and capabilities in cybersecurity, with a focus on placing graduates in federal/executive entities; and 4) advance cybersecurity awareness and competencies among K-12 students and educators.<br/><br/>This project is supported by the CyberCorps® Scholarship for Service (SFS) program, which funds proposals establishing or continuing scholarship programs in cybersecurity and aligns with the U.S. National Cyber Strategy to develop a superior cybersecurity workforce. Following graduation, scholarship recipients are required to work in cybersecurity for a federal, state, local, or tribal Government organization for the same duration as their scholarship support.<br/><br/>This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "6580", "attributes": { "award_id": "5P20GM103446-21", "title": "Delaware INBRE", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of General Medical Sciences (NIGMS)" ], "program_reference_codes": [], "program_officials": [ { "id": 22040, "first_name": "KRISHAN", "last_name": "ARORA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2001-09-30", "end_date": "2024-04-30", "award_amount": 4053243, "principal_investigator": { "id": 22041, "first_name": "MELINDA K", "last_name": "DUNCAN", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 442, "ror": "https://ror.org/01sbq1a82", "name": "University of Delaware", "address": "", "city": "", "state": "DE", "zip": "", "country": "United States", "approved": true }, "abstract": "– Overall The overall mission of the Delaware INBRE (DE-INBRE) program is to further grow a collaborative, multidisciplinary biomedical research network in Delaware that creates and supports sustainable collaborative research programs that address strategic health issues for the State, embraces diversity, and produces a positive impact on Delaware’s workforce and economy. The DE-INBRE network consists of six Partner Institutions: the lead institution, University of Delaware; three minority- serving primarily undergraduate institutions (PUIs), Delaware State University, Delaware Technical Community College, and Wesley College; and two medical institutions, Christiana Care Health System and Nemours/Alfred I. duPont Hospital for Children. Three Affiliated Institutions joined the network in 2017, including the Wilmington Veterans Affairs Medical Center, Wilmington University, and Delaware BioScience Association. The DE-INBRE’s five administrative and scientific cores provide research support and capacity building. The Administrative and Evaluation Core manages network activities with a rigorous evaluation program. A Centralized Shared Resources Core provides state-of-the-art research instrumentation and scientific expertise via a network of core facilities. A broadly engaged Bioinformatics Core supports inter-institutional research initiatives and training needs. The Education and Professional Development Core engages Delaware’s faculty, clinicians, and a diverse population of students with exceptional mentors. Finally, the Developmental Research Project Program supports Pilot Project investigators in cancer, cardiovascular, and neuroscience thematic areas. Specific Aims 1. Grow a strong and sustainable biomedical research capability in Delaware. 2. Enhance the capacity of Delaware’s biomedical research network. 3. Embrace diversity across Delaware’s biomedical research, industrial, and patient care networks. 4. Enhance the biomedical science and technology knowledge of Delaware’s workforce.", "keywords": [ "Address", "Area", "Award", "Basic Science", "Bioinformatics", "Biological Sciences", "Biomedical Research", "Brain", "Cardiovascular system", "Clinical", "Communities", "Core Facility", "Delaware", "Development", "Disease", "Economics", "Education", "Educational workshop", "Evaluation", "Faculty", "Funding", "Goals", "Grant", "Health", "Healthcare Systems", "Heart Diseases", "Industrialization", "Institution", "Knowledge", "Lead", "Malignant Neoplasms", "Medical", "Medical center", "Mentors", "Minority", "Minority Groups", "Mission", "Neurosciences", "Occupations", "Patient Care", "Pediatric Hospitals", "Peer Review", "Pilot Projects", "Population Heterogeneity", "Postdoctoral Fellow", "Program Evaluation", "Program Research Project Grants", "Publications", "Publishing", "Research", "Research Infrastructure", "Research Personnel", "Research Support", "Resource Sharing", "Risk", "Science", "Series", "Services", "Students", "Technology", "Training", "Training Activity", "Training and Education", "Translational Research", "Underrepresented Minority", "United States Department of Veterans Affairs", "Universities", "Woman", "cardiovascular health", "career", "college", "community college", "experience", "graduate student", "human capital", "improved", "improved outcome", "instrumentation", "inter-institutional", "meeting abstracts", "multidisciplinary", "programs", "student training", "symposium", "undergraduate student" ], "approved": true } } ], "meta": { "pagination": { "page": 1392, "pages": 1424, "count": 14236 } } }