Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=1385&sort=-start_date
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=-start_date", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1397&sort=-start_date", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1386&sort=-start_date", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1384&sort=-start_date" }, "data": [ { "type": "Grant", "id": "7629", "attributes": { "award_id": "3P30ES005022-33S1", "title": "A randomized crossover trial of portable air cleaners to reduce PM and SARS-CoV-2 exposures at home", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Environmental Health Sciences (NIEHS)" ], "program_reference_codes": [], "program_officials": [ { "id": 11803, "first_name": "Claudia L", "last_name": "Thompson", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1997-04-01", "end_date": "2024-03-31", "award_amount": 254770, "principal_investigator": { "id": 23428, "first_name": "HELMUT", "last_name": "ZARBL", "orcid": null, "emails": "[email protected]", "private_emails": null, "keywords": "[]", "approved": true, "websites": "[]", "desired_collaboration": "", "comments": "", "affiliations": [ { "id": 1418, "ror": "", "name": "RBHS-SCHOOL OF PUBLIC HEALTH", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1418, "ror": "", "name": "RBHS-SCHOOL OF PUBLIC HEALTH", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true }, "abstract": "Americans newly infected with SARS-CoV-2 (SC2) are directed to isolate at home with care provided by household members. Isolation from others may be difficult to maintain for 2 weeks, especially in economically challenged households without enough space to create a private sick room and bathroom. The CDC recommends that at-home patients and their caregivers use makeshift facemasks for care-giver protection. They do not address the possibility of virus spread via smaller particles that are not captured by improvised facemasks. Accumulating evidence supports the significance of patient-generated aerosols, with and without ambient PM, in the transmission of SC2 infection, but haven’t been subject to controlled study. U.S. PM2.5 concentrations are linked to a 15% increase in COVID-19 deaths per ?g/m3 of PM2.5, suggesting an interaction between the two stressors. Thus, we plan to quantify SC2 in different PM fractions in home isolation rooms of newly diagnosed individuals Moreover, a common recommendation to reduce indoor aerosol exposures is filtration, and based on our experience we plan a crossover trial of air cleaners in home isolation rooms. We hypothesize that portable indoor particle filters will reduce both airborne PM and associated viral particle concentrations in the air around patients. We aim to test this hypothesis by enrolling 20 individuals from our employee health clinics with newly diagnosed SC2 infections in a cross-over randomized trial of home air cleaners. These will be continuously operated alternately for two consecutive 24-hour cycles, one cycle with a HEPA filter, and the other with a sham filter. Size selective impactors in the isolation room will elucidate particle sizes most associated with virus. Samplers will allow capture of PM2.5, PM coarse (10-2.5), and >PM10 fractions. In both the isolation room and the main living area we will collect total inhalable particles (d<100 µm) at 10 L/min. These samples will be used in initial analyses to check if there is sufficient viral RNA in individual impactor stages for reliable detection and quantification. Concentrations of PM and virus will be compared between filtered and sham conditions .The greatest impact of our studies will be finding of a significant viral concentration in the aerosol range (specifically, particles < 10 µm) documenting the potential for aerosol exposure to SC2. Finding substantial viral content in aerosol size fractions will have additional public health implications, as preventing person-to-person aerosol transmission is more challenging than preventing transmission via larger droplets, the focus of almost all current prevention recommendations.", "keywords": [ "2019-nCoV", "Address", "Aerosols", "Air", "American", "Area", "Biological Assay", "COVID-19", "Cardiopulmonary", "Caregivers", "Caring", "Centers for Disease Control and Prevention (U.S.)", "Cessation of life", "Characteristics", "Clinic", "Clinical Trials", "Communities", "Controlled Study", "Cross-Over Trials", "Detection", "Development", "Devices", "Employee Health", "Enrollment", "Epidemiology", "Exposure to", "Extravasation", "Filtration", "Handwashing", "Home environment", "Hospitals", "Hour", "Household", "Individual", "Infection", "Lead", "Link", "Methodology", "Methods", "Morbidity - disease rate", "Newly Diagnosed", "Particle Size", "Particulate", "Pathogenesis", "Pathogenicity", "Patients", "Performance", "Persons", "Prevention", "Privatization", "Public Health", "RNA", "Randomized", "Recommendation", "Reporting", "Respiratory Tract Infections", "Saliva", "Sampling", "Satellite Viruses", "Security", "Single-Blind Study", "Source", "Testing", "Viral", "Virus", "air cleaner", "air filter", "air sampling", "base", "coarse particles", "effectiveness measure", "experience", "experimental study", "fine particles", "health care settings", "high efficiency particulate air filter", "indoor particulate matter", "laboratory experiment", "member", "mortality", "novel", "particle", "portability", "prevent", "racial disparity", "randomized trial", "stressor", "transmission process", "ventilation", "viral RNA" ], "approved": true } }, { "type": "Grant", "id": "7486", "attributes": { "award_id": "3P30CA013148-48S2", "title": "COVID-19 and Its Implications for Cancer Prevention and Control: A Collaborative Effort Across Cancer Centers", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Cancer Institute (NCI)" ], "program_reference_codes": [], "program_officials": [ { "id": 22891, "first_name": "Min", "last_name": "He", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1997-03-28", "end_date": "2022-03-31", "award_amount": 371250, "principal_investigator": { "id": 23288, "first_name": "BARRY P", "last_name": "SLECKMAN", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 612, "ror": "https://ror.org/008s83205", "name": "University of Alabama at Birmingham", "address": "", "city": "", "state": "AL", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 612, "ror": "https://ror.org/008s83205", "name": "University of Alabama at Birmingham", "address": "", "city": "", "state": "AL", "zip": "", "country": "United States", "approved": true }, "abstract": "The unexpected COVID-19 pandemic has the potential to trigger major behavior changes worldwide, which, consequently, may have significant implications for cancer prevention, management, and survivorship efforts, particularly among sub-populations experiencing cancer disparities. Thus, it is imperative to be prepared and adapt our ongoing and future strategies across the cancer care continuum within this new context through participatory evidence-based approaches. Given the urgency, and how rapidly these changes are occurring, we must take advantage of ongoing collaborative efforts to maximize resources and accelerate implementation of these new strategies based on the needs and wants of different sub-populations in the U.S. The overall goal of this collaborative with four other cancer centers (Iowa, Detroit, Colorado, and Ohio) is to work together to rapidly develop a standard set of core questions to incorporate into surveys that can be administered to populations across the U.S. using protocols that can be delivered by cancer center/university staff working remotely (e.g., online and telephone). Although five cancer centers are moving forward with the supplement, other cancer centers are willing to join our efforts so we have begun a coordinated effort to engage them in the process in the event additional resources become available. The specific aims are: 1. To assess how differences in demographics (rural/urban, age, gender, race, educational attainment) will impact engagement in cancer preventive behaviors (e.g., tobacco cessation) and cancer management/survivorship behaviors (e.g., adherence to treatment, adherence to surveillance) in the context of COVID-19 environmental constraints (e.g., social distancing, employment, mental health, etc.) among adult healthy volunteers, cancer patients, and cancer survivors in Alabama (field center); 2. To provide coordination of efforts and technical assistance regarding data management and analysis to all participating cancer centers (coordinating center); 3. To strengthen the collaboration with the participating cancer centers toward the development and implementation of cancer prevention & control strategies in the context of COVID-19 (coordinating center)", "keywords": [ "Address", "Adherence", "Adult", "African American", "Age", "Alabama", "Animal Model", "Area", "Arkansas", "B-Lymphocytes", "Behavior", "Behavior Therapy", "Biological Markers", "Body Weight", "Brain Neoplasms", "COVID-19", "COVID-19 pandemic", "Cancer Biology", "Cancer Center", "Cancer Control", "Cancer Patient", "Cancer Survivor", "Cancer Vaccines", "Catchment Area", "Chemopreventive Agent", "Clinic", "Clinical Trials", "Collaborations", "Colorado", "Comparative Effectiveness Research", "Comprehensive Cancer Center", "Continuity of Patient Care", "Data Analyses", "Deep South", "Detection", "Development", "Diagnosis", "Diagnostic", "Diet", "Disease", "Disease Progression", "Early Diagnosis", "Employment", "Event", "Functional Imaging", "Future", "Gender", "Gene Expression", "Genomic Instability", "Genotype", "Goals", "Health Services Accessibility", "Heart", "Human", "Human Biology", "Imaging technology", "Immunology", "Immunotherapeutic agent", "Incidence", "Industry", "Inflammation", "Interdisciplinary Study", "Intervention", "Investigation", "Iowa", "Knowledge", "Laboratories", "Link", "Louisiana", "Malignant Neoplasms", "Malignant neoplasm of brain", "Mental Health", "Mission", "Mississippi", "Molecular and Cellular Biology", "Morbidity - disease rate", "Neoplasm Metastasis", "Obesity", "Ohio", "Outcome", "Outcomes Research", "Pathogenesis", "Pathway interactions", "Patients", "Pharmacology", "Phase", "Phenotype", "Physical activity", "Population", "Predisposition", "Prevention", "Preventive", "Process", "Protocols documentation", "Public Health", "Quality of life", "Race", "Recording of previous events", "Research", "Resources", "Risk", "Rural", "Scientist", "Signal Transduction", "Social Distance", "Surveys", "Systems Biology", "T-Lymphocyte", "Telephone", "Testing", "Therapeutic", "Tobacco Use Cessation", "Tobacco use", "Translating", "Translational Research", "Translations", "Universities", "Vision", "Work", "base", "behavior change", "biomarker identification", "cancer biomarkers", "cancer care", "cancer cell", "cancer health disparity", "cancer prevention", "cancer risk", "cancer stem cell", "carcinogenesis", "cell behavior", "data management", "demographics", "dietary manipulation", "drug development", "drug discovery", "end of life", "energy balance", "evidence base", "experience", "healthy volunteer", "high risk population", "improved", "innovation", "mortality", "new therapeuti" ], "approved": true } }, { "type": "Grant", "id": "7487", "attributes": { "award_id": "3P30CA013148-48S5", "title": "COMPREHENSIVE CANCER CENTER CORE SUPPORT GRANT", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Cancer Institute (NCI)" ], "program_reference_codes": [], "program_officials": [ { "id": 22891, "first_name": "Min", "last_name": "He", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1997-03-28", "end_date": "2022-03-31", "award_amount": 100000, "principal_investigator": { "id": 23288, "first_name": "BARRY P", "last_name": "SLECKMAN", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 612, "ror": "https://ror.org/008s83205", "name": "University of Alabama at Birmingham", "address": "", "city": "", "state": "AL", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 612, "ror": "https://ror.org/008s83205", "name": "University of Alabama at Birmingham", "address": "", "city": "", "state": "AL", "zip": "", "country": "United States", "approved": true }, "abstract": "OVERALL COMPONENT ABSTRACT The UAB CCC is the only NCI designated comprehensive cancer center in the states of Alabama, Mississippi, Louisiana and Arkansas, states with higher cancer mortality and significant minority, mostly African American populations. The Cancer Center is in its 44th year of NCI funding and continues its major contributions to translational therapeutics and cancer disparity research with a focus on training minority investigators. The UAB CCC has 242 members who come from 30 departments in 9 UAB schools, Southern Research, and HudsonAlpha Institute for Biotechnology. The members are supported by $92,055,777 in annual direct extramural funding. The UAB CCC is organized into six research programs, two each in basic, translational, and prevention and control – Inflammation, Immunology & Immunotherapeutics; Cancer Cell Biology; Experimental Therapeutics; Neuro-Oncology; Cancer Chemoprevention; and Cancer Control & Population Sciences. Members published 1,684 cancer focused, peer reviewed publications between 2011 and 2015 of which 24% were intra-programmatic, 16% inter-programmatic, and 53% inter-institutional. These members are supported by eleven shared facilities – Biostatistics & Bioinformatics, Comprehensive Genomics, High Resolution Imaging, Human Imaging, Mass Spectrometry/2D Proteomics, Microbiome/Gnotobiotic, Preclinical Imaging, Recruitment & Retention, Structural Biology, Tissue Procurement, and Transgenic Animals as well as the developing Pharmacometrics Shared Facility. We have established a Phase I Clinical Trials Program, opened an Advanced Imaging Facility, advanced targets through the Alabama Drug Discovery Alliance, created the UAB Health System Cancer Community Network, and are now a consortium with HudsonAlpha Institute for Biotechnology. In addition to these achievements, we have created an Institute for Cancer Outcomes and Survivorship, and established a critical mass of investigators in energy balance and cancer. We have also expanded our minority training programs that since 2005 have trained 59 scholars resulting in 306 publications, 67 grant submissions with 30 funded, and have had a major impact at Morehouse School of Medicine and Tuskegee University. We have recruited 47 investigators to multiple programs in the Cancer Center since 2010. Strategic plans developed in 2011 with crosscutting themes of Translational Therapeutics, Systems Biomedicine, and Energetics and Cancer continue to be highly relevant today. For the future, we will continue to emphasize translational and cancer disparity research with an emphasis on personalized/genomic medicine, energy balance and cancer, outcomes and survivorship, and early phase clinical trials.", "keywords": [ "Achievement", "Address", "African American", "Age", "Alabama", "Animal Model", "Area", "Arkansas", "B-Lymphocytes", "Behavior Therapy", "Bioinformatics", "Biological Markers", "Biometry", "Biotechnology", "Body Weight", "Brain Neoplasms", "Cancer Biology", "Cancer Center", "Cancer Control", "Cancer Survivor", "Cancer Vaccines", "Catchment Area", "Cellular biology", "Chemopreventive Agent", "Clinic", "Clinical Trials", "Community Networks", "Comparative Effectiveness Research", "Comprehensive Cancer Center", "Deep South", "Detection", "Development", "Diagnosis", "Diagnostic", "Diet", "Disease", "Disease Progression", "Early Diagnosis", "Extramural Activities", "Functional Imaging", "Funding", "Future", "Gene Expression", "Genomic Instability", "Genomics", "Genotype", "Gnotobiotic", "Goals", "Grant", "Health Services Accessibility", "Health system", "Heart", "Human", "Human Biology", "Imaging technology", "Immunology", "Immunotherapeutic agent", "Incidence", "Industry", "Inflammation", "Institutes", "Interdisciplinary Study", "Intervention", "Investigation", "Investigational Therapies", "Knowledge", "Laboratories", "Link", "Louisiana", "Malignant Neoplasms", "Malignant neoplasm of brain", "Mass Spectrum Analysis", "Minority", "Mission", "Mississippi", "Molecular and Cellular Biology", "Morbidity - disease rate", "Morehouse School of Medicine", "Neoplasm Metastasis", "Obesity", "Outcome", "Outcomes Research", "Pathogenesis", "Pathway interactions", "Patients", "Peer Review", "Pharmacology", "Phase", "Phase I Clinical Trials", "Phenotype", "Physical activity", "Population", "Population Sciences", "Predisposition", "Prevention", "Proteomics", "Public Health", "Publications", "Publishing", "Quality of life", "Recording of previous events", "Research", "Research Personnel", "Risk", "Schools", "Scientist", "Signal Transduction", "Strategic Planning", "System", "Systems Biology", "T-Lymphocyte", "Testing", "Therapeutic", "Tissue Procurements", "Tobacco use", "Training", "Training Programs", "Transgenic Animals", "Translating", "Translational Research", "Translations", "Universities", "Vision", "Work", "biomarker identification", "cancer biomarkers", "cancer cell", "cancer chemoprevention", "cancer health disparity", "cancer risk", "cancer stem cell", "carcinogenesis", "cell behavior", "dietary manipulation", "drug development", "drug discovery", "early phase clinical trial" ], "approved": true } }, { "type": "Grant", "id": "6267", "attributes": { "award_id": "3P01AG005842-32S2", "title": "Improving Health Outcomes for an Aging Population", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 21194, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1997-02-01", "end_date": "2023-06-30", "award_amount": 161388, "principal_investigator": { "id": 21195, "first_name": "Katherine", "last_name": "Baicker", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 739, "ror": "https://ror.org/04grmx538", "name": "National Bureau of Economic Research", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 739, "ror": "https://ror.org/04grmx538", "name": "National Bureau of Economic Research", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "Drug Treatments and the Impact of COVID-19 on Alzheimer’s Patients and Other Vulnerable Populations Interventions in health policy and care management have the potential to reduce COVID-19 infections and deaths, particularly if they can be targeted to the most vulnerable populations such as patients with Alzheimer's Disease and Related Dementias (ADRD). In this supplement proposal, we compile information and develop tools that can accelerate and target such interventions. The first aim is to identify the medical and socioeconomic characteristics of people that make them most vulnerable to COVID-19. We create cohorts of patients with ADRD and for other vulnerable populations based on their Fall 2019 characteristics, and follow them through 2020 to identify those at greatest risk of both “direct” COVID-19 outcomes (e.g., critical illness, mortality) and “indirect” increases in non-COVID outcomes. The second aim is an ambitious proof of concept: using natural experiments to shed light on novel drugs to treat or prevent COVID-19 with a particular focus on drugs most heavily used by ADRD patients (e.g., anticholinesterase inhibitors). We will develop and apply a machine learning approach to test the potential effect of drug classes on COVID-19, measured by diagnosis, hospitalization, ICU admission, and death. This supplement is made possible by a unique opportunity: Access to near-real-time Medicare claims data (one-month lag), which CMS appears willing to make available through an expedited data use agreement. The application will supplement an ongoing program project on Improving Health Outcome for an Aging Population, whose overarching aim is to better understand health trends and disparities, determinants of health, and approaches to improving health for an aging population in an evolving landscape.", "keywords": [ "Address", "Administrative Supplement", "Admission activity", "Affect", "Age", "Agreement", "Alzheimer&apos", "s disease patient", "Alzheimer&apos", "s disease related dementia", "Angiotensin-Converting Enzyme Inhibitors", "Back", "Biological", "COVID-19", "COVID-19 pandemic", "Caring", "Cessation of life", "Characteristics", "Cholinesterase Inhibitors", "Chronic", "Clinical", "Code", "Collaborations", "Communities", "Contracts", "Critical Illness", "Data", "Data Scientist", "Development", "Diagnosis", "Disease", "Elderly", "Emergency Situation", "Ethnic Origin", "Formularies", "Future", "General Population", "Geography", "Health", "Health Policy", "Health trends", "Healthcare", "Hospitalization", "Hydroxychloroquine", "Infection", "Institution", "Intervention", "Light", "Location", "Low income", "Machine Learning", "Measures", "Mediating", "Medicaid eligibility", "Medical", "Medicare claim", "Memantine", "Methods", "Modernization", "Natural experiment", "Nursing Homes", "Older Population", "Outcome", "Patients", "Pharmaceutical Preparations", "Pharmacologic Substance", "Pharmacotherapy", "Physician&apos", "s Practice Patterns", "Policies", "Population", "Population Density", "Population Intervention", "Race", "Randomized", "Research", "Risk", "Socioeconomic Factors", "Testing", "Time", "Triage", "Vulnerable Populations", "Work", "adverse outcome", "aged", "aging population", "base", "cohort", "drug candidate", "falls", "geographic difference", "health disparity", "health management", "high risk", "improved", "inhibitor/antagonist", "insight", "mortality", "novel therapeutics", "parent grant", "population based", "prevent", "programs", "socioeconomics", "tool" ], "approved": true } }, { "type": "Grant", "id": "6268", "attributes": { "award_id": "3P01AG005842-32S1", "title": "Improving Health Outcomes for an Aging Population", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 21196, "first_name": "PARTHA", "last_name": "BHATTACHARYYA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1997-02-01", "end_date": "2023-06-30", "award_amount": 447421, "principal_investigator": { "id": 21197, "first_name": "Katherine", "last_name": "Baicker", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 739, "ror": "https://ror.org/04grmx538", "name": "National Bureau of Economic Research", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "Supplemental Project: The Impact of the COVID-19 Pandemic and Subsequent Economic Downturn on Population Health and Mortality This project supplements an ongoing program project on “Improving Health Outcomes for an Aging Population” by analyzing the impact of the COVID-19 pandemic and its associated economic downturn on population health and mortality. As significant as the reported mortality statistics from COVID-19 have become, they do not account for undiagnosed cases of COVID-19, the health and mortality costs of deferred or foregone care for other conditions, or the secondary health effects of economic distress, job loss, and social isolation. Also absent is any understanding of how these wider health effects are influenced by policy responses, notably social distancing requirements at the local and state levels, and their associated effects on business activity. While COVID-19 is fundamentally a public health crisis, focusing exclusively on its direct health effects, without accounting for the impact on the health care system and the economy -- and in turn the economy’s impact on health, provides an incomplete understanding of the pandemic’s overall impact on health and wellbeing. The goal of this supplement is to engage a small network of economic scholars to analyze near real-time data on health and mortality, and to begin to unravel these indirect and secondary health implications of the pandemic. The supplement’s aims encompass three categories of analysis on the secondary impact of the pandemic on health and mortality: (1) other health conditions affected indirectly by the pandemic, and how both the direct and indirect health impacts vary across race, ethnicity, and socioeconomic groups; (2) the dramatic economic downturn of the pandemic and the distinct impact of economic conditions on health and mortality; and (3) the social distancing policy response of different communities and states, and its relationship to economic conditions, health and mortality at the local and state levels.", "keywords": [ "Accounting", "Affect", "Age", "Businesses", "COVID-19", "COVID-19 pandemic", "Caring", "Case Study", "Categories", "Cause of Death", "Cessation of life", "Communities", "Coronavirus", "Data", "Diagnosis", "Distress", "Economic Conditions", "Economics", "Ensure", "Ethnic Origin", "Face", "Geographic Locations", "Geography", "Goals", "Government", "Health", "Health trends", "Healthcare", "Healthcare Systems", "Incubated", "Infection", "Information Dissemination", "Investigation", "Left", "Medicare claim", "Modeling", "Modernization", "Motor Vehicles", "Occupations", "Outcome", "Personal Satisfaction", "Physiological", "Policies", "Population Analysis", "Public Health", "Race", "Records", "Reporting", "Research Personnel", "Social Distance", "Social isolation", "Socioeconomic Status", "Testing", "Time", "Unemployment", "United States", "Work", "aging population", "base", "beneficiary", "career", "coronavirus disease", "cost", "economic impact", "health disparity", "improved", "infection rate", "meetings", "mortality", "mortality statistics", "pandemic disease", "parent grant", "population health", "programs", "response", "socioeconomics", "symposium" ], "approved": true } }, { "type": "Grant", "id": "5951", "attributes": { "award_id": "3P60AA009803-28S2", "title": "LSUHSC-NO Comprehensive Alcohol-HIV/AIDS Research Center", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Alcohol Abuse and Alcoholism (NIAAA)" ], "program_reference_codes": [], "program_officials": [ { "id": 20380, "first_name": "LI", "last_name": "Lin", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1996-12-01", "end_date": "2024-11-30", "award_amount": 109700, "principal_investigator": { "id": 20381, "first_name": "PATRICIA E.", "last_name": "MOLINA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1202, "ror": "", "name": "LSU HEALTH SCIENCES CENTER", "address": "", "city": "", "state": "LA", "zip": "", "country": "United States", "approved": true }, "abstract": "LSUHSC CARC Overall The Louisiana State University Health Sciences Center New Orleans (LSUHSC-NO) Comprehensive Alcohol- HIV/AIDS Research Center (CARC) is a multi-institutional, multidisciplinary team of scientists from LSUHSC and the Tulane National Primate Research Center (TNPRC) and School of Public Health and Tropical Medicine (TSPHTM) with a research focus on the interaction of alcohol use disorder (AUD), human immunodeficiency virus (HIV), and antiretroviral therapy (ART). The translational focus is the impact of at-risk alcohol consumption on risk for comorbidities in a longitudinal cohort of in-care virally-suppressed persons living with HIV (PLWH). We have demonstrated the relevance of the simian immunodeficiency virus (SIV) nonhuman primate (NHP) model to the clinical setting, revealed the deleterious impact of alcohol despite viremic control in in-care PLWH, and identified environmental (neighborhood) and behavioral (diet) factors that affect disease course and severity. The proposed studies evolve, expand, and refine our research strategy to a mechanistic bidirectional (NHP‒ PLWH‒NHP) translational investigation of the impact of AUD, HIV, and ART on comorbid conditions in an underserved cohort of PLWH. The scientific premise of the proposed studies is the observation that intestinal mucosa is an early site of alcohol-induced immunopathogenic changes in the alcohol-consuming, HIV/SIV- infected host that culminates in loss of mucosal barrier function and gut leak that promotes chronic immune activation, inflammation, and senescence, which we hypothesize increases risk for comorbidities in PLWH. An Administrative Core provides oversight, supports data management and analysis, and funds pilot projects to promote novel research investigations. Four Research Components (RCs) study in-care underserved PLWH and a sex- and age-matched HIV- control group, complemented by mechanistic studies in SIV+ and SIV- NHPs. RC1 investigates the impact of community and interpersonal stress on behavioral and chronic comorbidities among PLWH and the unique role that alcohol consumption plays in the pathways. RC2 and RC3 elucidate pathophysiological mechanisms of two comorbidities: metabolic dysregulation and neurological deficits. RC4 investigates the immunological mechanisms driving the balance between immune activation and activation- induced cell death that contribute to cell senescence and tissue injury with alcohol exposure. An Experimental and Analytical Resource Core provides support for all proposed studies. An Information Dissemination Core promotes training and accelerates the translation and dissemination of research findings to the scientific, health care, and lay communities. The CARC will continue to leverage and synergize with existing institutional resources. Access to a unique HIV+ population in a southeast urban region, the established expertise of CARC investigators in biomedical and behavioral research, state-of-the-art research facilities, outstanding scientific environment, and strong institutional support will ensure that the proposed CARC projects will continue to advance our understanding of the comorbid consequences of AUD, HIV/SIV, and ART in PLWH.", "keywords": [ "AIDS/HIV problem", "Address", "Affect", "Age", "Aging", "Alcohol consumption", "Alcohols", "Automobile Driving", "Behavior", "Behavioral", "Behavioral Research", "Biological Process", "Biomedical Research", "Caring", "Cell Aging", "Cell Death", "Center for Translational Science Activities", "Chronic", "Clinical", "Clinical Research", "Communities", "Complement", "Control Groups", "Data", "Data Analyses", "Development", "Diet", "Disadvantaged", "Disease", "Enrollment", "Ensure", "Environment", "Environmental Risk Factor", "Equilibrium", "Evolution", "Exposure to", "Funding", "Gut Mucosa", "HIV", "HIV therapy", "Health", "Health Sciences", "Healthcare", "Immune", "Immunologics", "Individual", "Inflammation", "Inflammatory", "Information Dissemination", "Infrastructure", "Intestinal Mucosa", "Investigation", "Knowledge", "Longitudinal Studies", "Longitudinal cohort", "Louisiana", "Mentors", "Metabolic", "Minority Groups", "Modeling", "Mucous Membrane", "Neighborhoods", "Neurologic Deficit", "Oxidative Stress", "Pathway interactions", "Persons", "Physical activity", "Pilot Projects", "Play", "Population", "Primates", "Productivity", "Public Health Schools", "Publishing", "Research", "Research Personnel", "Resources", "Risk", "Role", "SIV", "Scientist", "Severities", "Site", "Stress", "Training", "Translational Research", "Translations", "Tropical Medicine", "Universities", "Viral", "alcohol consequences", "alcohol effect", "alcohol exposure", "alcohol risk", "alcohol use disorder", "antiretroviral therapy", "career development", "clinically relevant", "cohort", "comorbidity", "data management", "demographics", "experience", "immune activation", "multidisciplinary", "nonhuman primate", "novel", "organizational structure", "preclinical study", "programs", "research facility", "senescence", "sex", "simian human immunodeficiency virus", "social factors", "stressor", "substance use", "tissue injury", "translational study", "underserved minority", "urban area" ], "approved": true } }, { "type": "Grant", "id": "6822", "attributes": { "award_id": "2P30CA014089-46", "title": "Clinical Protocol and Data Management", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Cancer Institute (NCI)" ], "program_reference_codes": [], "program_officials": [], "start_date": "1996-12-01", "end_date": "2026-11-30", "award_amount": 729482, "principal_investigator": { "id": 22645, "first_name": "Anthony Boutros", "last_name": "El-Khoueiry", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 152, "ror": "https://ror.org/03taz7m60", "name": "University of Southern California", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 152, "ror": "https://ror.org/03taz7m60", "name": "University of Southern California", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "- Clinical Protocol and Data Management (CPDM) At the USC Norris Comprehensive Cancer Center (NCCC), the Clinical Investigations Support Office (CISO) serves as the centralized clinical trials office for all cancer trials, independent of originating department or disease team. The senior CISO leadership includes Anthony El-Khoueiry MD who serves as the Medical Director, Kevin Kelly MD who serves as the Assistant Medical Director, and Zeno Ashai MBBS MPH who was appointed as Associate Director in 2019. CISO has three units: the Quality Assurance and Compliance Unit, the Regulatory Unit and the Research Operations Unit. CISO also supports the four clinical research oversight committees (Clinical Investigations Committee, Data Safety and Monitoring Committee, Quality Assurance Committee, and Phase I Committee). In the current period, CISO created a role for Disease Team Managers who supervise research staff and support the ten Disease Teams in Step 1 of Disease Team protocol reviews. Notably, CISO also expanded and enhanced services to support investigator initiated trials (IITs) over this grant period, including: new protocol development support (design and feasibility consultation meetings), addition of a protocol writer, Medidata Rave database development for interventional protocols, and multisite coordination services (enabling NCCC to serve as a coordinating site for multi-site IITs when appropriate; 14 such trials coordinated in 2019). Additional accomplishments over the grant period include: 1) an extensive CISO reorganization with addition of 20 full time employees (FTEs), enabling expansion of services cited above; 2) full implementation of the OnCore clinical trials management system; 3) a 43.5% increase in interventional trial accruals from 816 patients in 2015 to 1171 in 2019 (of which 223 (29%) were IITs); 4) a 57% decrease in time to activation from 42 weeks in 2015 to 18 weeks in 2019; 5) improvement in the quality of IITs that reduced the disapproval rate at the initial PRMS review from 35% in 2015 to 17% in 2019; and 6) substantial accrual of minorities in interventional trials (61.6% of 2019 accruals are from minority groups underrepresented in clinical trials). Despite the COVID- 19 pandemic, 659 patients were accrued to interventional trials from 1/1/2020 to 11/30/2020.", "keywords": [ "Administrator", "Asians", "COVID-19 pandemic", "California", "Cancer Center Support Grant", "Case Report Form", "Catchment Area", "Clinical", "Clinical Cancer Center", "Clinical Data", "Clinical Management", "Clinical Protocols", "Clinical Research", "Clinical Trials", "Communities", "Community Outreach", "Comprehensive Cancer Center", "Consultations", "Data", "Data Science", "Databases", "Development", "Disease", "Education and Outreach", "Eligibility Determination", "Employee", "Ensure", "Environment", "Evaluation", "Faculty", "Generations", "Grant", "Institution", "Intervention Trial", "Last Name", "Leadership", "Longevity", "Malignant Neoplasms", "Medidata", "Minority", "Minority Groups", "Mission", "Monitor", "Names", "Operations Research", "Participant", "Patients", "Phase", "Physician Executives", "Procedures", "Process", "Protocols documentation", "Regulation", "Reporting", "Research", "Research Personnel", "Resource Sharing", "Role", "Safety", "Services", "Site", "Standardization", "Supervision", "System", "Time", "Training", "Underrepresented Populations", "Universities", "University of Southern California Norris Cancer Center", "Update", "Woman", "Work", "base", "cancer clinical trial", "clinical investigation", "community engagement", "data management", "design", "education planning", "financial toxicity", "investigator-initiated trial", "meetings", "member", "minority patient", "multidisciplinary", "programs", "protocol development", "quality assurance", "service coordination", "therapy development", "tool" ], "approved": true } }, { "type": "Grant", "id": "7287", "attributes": { "award_id": "3P60AA009803-27S3", "title": "LSUHSC-NO Comprehensive Alcohol-HIV/AIDS Research Center", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 8668, "first_name": "LI", "last_name": "Lin", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1996-12-01", "end_date": "2024-11-30", "award_amount": 102458, "principal_investigator": { "id": 12660, "first_name": "PATRICIA E.", "last_name": "MOLINA", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1202, "ror": "", "name": "LSU HEALTH SCIENCES CENTER", "address": "", "city": "", "state": "LA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1202, "ror": "", "name": "LSU HEALTH SCIENCES CENTER", "address": "", "city": "", "state": "LA", "zip": "", "country": "United States", "approved": true }, "abstract": "Administrative Supplement Research Component 1 (RC1) Comprehensive Alcohol Research Center. Community and Interpersonal Stress, Alcohol, and Chronic Comorbidities among PLWH. Louisiana had the third highest rates of SARS-CoV-2 cases and the second highest deaths per capita in the country during the peak of the COVID-19 pandemic. The alarming high rate of mortality in New Orleans led to strict government issued mandates for social distancing, self-quarantine, and shelter-in-place measures adding challenges like unemployment, loss of social networks, fear, and decreased access to personally delivered healthcare to the most vulnerable individuals. These stressful factors negatively impact pre-existing symptoms of stress, anxiety, and depression and may have unwanted consequences that contribute to morbidity and mortality of vulnerable populations. Persons living with HIV (PLWH) have an excessively high rate of exposure to chronic and lifetime social stressors, that are linked to elevated rates of poorer mental health including depressive disorders, alcohol use disorders (AUD), and post-traumatic stress disorder (PTSD). Alcohol consumption tends to increase during times of duress and uncertainty, and alcohol is often misused to cope with stress, anxiety, and other uncomfortable emotions. Psychiatric comorbidities decrease adherence to antiretroviral therapy and increase risk for substance use that together may increase risk for comorbidities or negatively impact disease progression particularly in aging PLWH. Heightened psychosocial and physiological stress among PLWH is associated with poorer immune status, increased viral load over time, faster disease progression, and higher rates of mortality. Our overarching hypothesis is that PLWH with AUD experience greater psychobehavioral and biological consequences of the COVID-19 pandemic. This administrative supplement proposes studies within the scope of those proposed in Specific Aim 1 of RC1: To examine the impact of neighborhood and interpersonal stress on alcohol use and its associated comorbidities in PLWH. This aim tests the hypotheses that a) Contextual stressors will be associated with alcohol use as well as clinical comorbidities (e.g., mental health, cardiometabolic conditions, neurocognitive impairment, and frailty) and b) Alcohol use mediates the relation between stress and clinical comorbidities. We propose to obtain self-reported measures of stress, anxiety, depression, and alcohol use of PLWH and HIV seronegative subjects enrolled in our longitudinal New Orleans Alcohol Use in HIV (NOAH) study during the pandemic. Quantitative and qualitative data collected during the government mandated shelter-in-place and within 2 months of reopening of the city will be integrated with individual level demographic, clinical (including serological immunological evidence of exposure), behavioral (alcohol use), and disease-specific (HIV viral loads and CD4/CD8 counts) data to determine the impact of COVID-19 related stress on drinking behavior, adherence to ART, and manifestation of anxiety symptoms. Moreover, we will elucidate the interaction of COVID-19 related stress and alcohol drinking during this stressful period with risk for comorbidities in PLWH and HIV seronegative individuals. These studies directly integrate in the overall framework of our center and leverage existing infrastructure to maximize data collection during this unique timeframe.", "keywords": [ "2019-nCoV", "AIDS/HIV problem", "Adherence", "Administrative Supplement", "Aging", "Alcohol consumption", "Alcohol or Other Drugs use", "Alcohols", "Anxiety", "Behavioral", "Behavioral Mechanisms", "Biological", "CD8B1 gene", "COVID-19", "COVID-19 pandemic", "Cessation of life", "Chronic", "Cities", "Clinical", "Cognitive", "Communities", "Country", "Data", "Data Collection", "Depressive disorder", "Disease", "Disease Progression", "Emotions", "Enrollment", "Exposure to", "Fright", "Government", "HIV", "HIV Seronegativity", "HIV therapy", "Health Sciences", "Healthcare", "Household", "Immunologics", "Individual", "Infrastructure", "Link", "Louisiana", "Measures", "Mediating", "Medical", "Mental Depression", "Mental Health", "Morbidity - disease rate", "Neighborhoods", "Neurocognitive Deficit", "Outcome", "Participant", "Pathway interactions", "Patient Self-Report", "Persons", "Physiological", "Play", "Post-Traumatic Stress Disorders", "Psyche structure", "Psychosocial Stress", "Quarantine", "Request for Proposals", "Research", "Risk", "Role", "Serological", "Shelter facility", "Social Distance", "Social Environment", "Social Network", "Stress", "Testing", "Time", "Uncertainty", "Unemployment", "Universities", "Viral", "Viral Load result", "Vulnerable Populations", "alcohol research", "alcohol use disorder", "antiretroviral therapy", "anxiety symptoms", "base", "behavioral adherence", "cardiometabolism", "community center", "comorbid depression", "comorbidity", "coping mechanism", "coronavirus disease", "disorder risk", "drinking behavior", "experience", "frailty", "high risk drinking", "immune activation", "immunological status", "mortality", "pandemic disease", "psychosocial", "sample collection", "social stressor", "stress symptom", "stressor" ], "approved": true } }, { "type": "Grant", "id": "6596", "attributes": { "award_id": "5R01ES008739-24", "title": "The Effect of Pesticide Exposure on Cognitive and Brain Development in Latino Children: PACE5", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Environmental Health Sciences (NIEHS)" ], "program_reference_codes": [], "program_officials": [ { "id": 22107, "first_name": "Claudia L", "last_name": "Thompson", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1996-09-30", "end_date": "2023-05-31", "award_amount": 563104, "principal_investigator": { "id": 22108, "first_name": "Thomas A.", "last_name": "Arcury", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 22109, "first_name": "Paul", "last_name": "Laurienti", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 1149, "ror": "", "name": "WAKE FOREST UNIVERSITY HEALTH SCIENCES", "address": "", "city": "", "state": "NC", "zip": "", "country": "United States", "approved": true }, "abstract": "Concern is mounting that commonly used pesticides are detrimental to children. Children are rapidly undergoing cognitive, sensory, and motor development, and disruption of normal maturation can have life-long consequences. The extant literature strongly indicates that prenatal exposure to pesticides leads to abnormal neurobehavioral development. A recent brain imaging study further showed that prenatal pesticide exposure is associated with disrupted anatomical brain development. However, results concerning the consequences of postnatal pesticide exposure are much less conclusive. Some studies have reported neurobehavioral deficits following postnatal pesticide exposure, but just as many studies have reported no negative consequences. Currently there are no studies that assess the effects of postnatal pesticide exposure on brain development using anatomical or functional brain imaging. More conclusive research on the effects of postnatal exposure on neurodevelopment requires a highly exposed population, a longitudinal design, and careful quantification of exposure and outcomes. We propose a two-group, prospective, longitudinal study of Latino children 7 years of age with quarterly measurement of cumulative pesticide exposure using passive dosimetry wristbands as well as documentation of prenatal and early life exposure through life history techniques. Children from Latino seasonal farmworker families will be compared with children from Latino families not participating in farm work and not living in an agricultural environment. Children in Latino farmworker families are at particularly high risk of exposure. Not only are pesticides frequently used in their low quality housing, but they are also exposed to agricultural pesticides used in nearby fields brought home by parental/sibling farmworkers on clothing. Children will be followed for 2 years with measurement of neurobehavioral function at baseline, 1 year, and 2 years. Neuroimaging will be performed in a subset of participants with structural and functional brain organization assessed at baseline and two years later. Specific aims for this project are: Aim 1: Compare 2-year longitudinal and prenatal/early life pesticide exposure between children of Latino seasonal farmworkers and children of Latino parents who are not farmworkers. Aim 2: Compare 2-year longitudinal neurobehavioral and emotional and behavioral functioning among children of Latino seasonal farmworkers relative to children of Latino parents who are not farmworkers. Aim 3: Compare 2-year longitudinal anatomical and functional brain development between children of Latino seasonal farmworkers and children of Latino parents who are not farmworkers. Our nearly two decades of environmental justice (EJ) and community-based participatory research (CBPR) on pesticide exposure with farmworkers and their families provides an auspicious context to engage this vulnerable population in a study of both scientific and environmental justice importance.", "keywords": [ "7 year old", "Address", "Affect", "Agriculture", "Anatomy", "Area", "Behavioral", "Blood", "Brain", "Brain imaging", "Calendar", "Chemicals", "Child", "Child Development", "Childhood", "Cholinesterases", "Chronic", "Clothing", "Cognitive", "Communities", "Complex", "Conflict (Psychology)", "Development", "Disease", "Documentation", "Dose", "Emotional", "Environment", "Environmental Risk Factor", "Exhibits", "Exposure to", "Family", "Farming environment", "Goals", "Home", "Housing", "Individual", "Latino", "Life", "Literature", "Longevity", "Longitudinal Studies", "Measurement", "Measures", "Metabolism", "Motor", "National Institute of Environmental Health Sciences", "Neurocognitive", "Organophosphates", "Outcome", "Parents", "Participant", "Performance", "Pest Control", "Pesticides", "Population", "Predisposition", "Published Comment", "Reporting", "Research", "Risk", "Sampling", "Schools", "Sensory", "Siblings", "Socioeconomic Status", "Strategic Planning", "Structure", "Study of Latinos", "Surface", "Techniques", "Time", "Vulnerable Populations", "Work", "agricultural pesticide", "community based participatory research", "developmental disease", "disorder risk", "dosimetry", "early life exposure", "environmental health disparity", "environmental justice", "farm worker", "gray matter", "health disparity", "high risk", "imaging study", "life history", "longitudinal design", "neurobehavioral", "neurodevelopment", "neuroimaging", "neuroimaging marker", "neurotoxic", "peer", "pesticide exposure", "postnatal", "prenatal", "prenatal exposure", "prospective", "stressor" ], "approved": true } }, { "type": "Grant", "id": "6351", "attributes": { "award_id": "3U45ES007850-26S1", "title": "OAI Consortium: Hazardous Waste Worker Training Program (HWWTP) and Environmental Career Worker Training Program (ECWTP)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Environmental Health Sciences (NIEHS)" ], "program_reference_codes": [], "program_officials": [ { "id": 21407, "first_name": "Sharon", "last_name": "Beard", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "1995-09-30", "end_date": "2022-05-31", "award_amount": 300000, "principal_investigator": { "id": 21408, "first_name": "Salvatore", "last_name": "Cali", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1453, "ror": "", "name": "OAI, INC.", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 1453, "ror": "", "name": "OAI, INC.", "address": "", "city": "", "state": "IL", "zip": "", "country": "United States", "approved": true }, "abstract": "OVERALL - PROJECT SUMMARY/ABSTRACT OAI, a Chicago community-based agency, proposes to implement HWWT and ECWT Consortia. HWWT will target three populations: 1) underfunded rural and volunteer Emergency First Responders 2) Transitional and Temporary Workers and high school dropouts, and 3) Non Union Workers, including Hispanic hazardous waste handlers. Over 5 years, HWWT will train 23,470 students in 19 states and generate 253,660 contact hours. ECWT will assist unemployed African Americans, Hispanics, women, ex-offenders, and veterans who face multiple barriers to employment in Chicago, Dallas and Kansas City by training a total of 420 participants, placing 355 (85%) in jobs and generating 169,440-211,800 instructional contact hours. Significance: Both Consortia target the underserved and address public health disparities, prevention, and protection of workers, EJ residents and their communities from exposure to hazardous substances. ECWT responds to the underrepresentation of disadvantaged residents in the construction/environmental workforce. Leadership and Capacity: OAI has been a WTP grantee since 1995, led by the same PI who has 32 years of experience in adult education, workforce development, and grants management. She will be supported by a team of health and safety professionals (IH, CIH) and others with requisite credentials and proven expertise. Innovation: Best practices and innovations of both Consortia include: the implementation of Social Ecological Model (SEM) and Economic Impact Study evaluation plan, integration of Climate Change and Community Resiliency into existing curricula, and Blended Learning. ECWT will continue to refine a unique Try-Outs selection process and demonstrate the Alumni Mentors retention strategy. HWWT will pilot a bilingual Train-the-Trainer model for Vietnamese nail salon workers integrating hazard awareness, SEM, 3Rs (reduction, reuse, and recycling), cultural competence, and community resiliency. Approach: HWWT will deliver direct training instruction via local peer trainers. As a strategy to build local capacity and sustainability, it will customize its Train-the-Trainer model to meet the needs of target populations. ECWT will provide Core Health & Safety Courses; Career Specific Training (Environmental/ Construction, Commercial Truck Driving/Hazmat Endorsement & Warehousing training, Water & Wastewater Operations, and Advanced Construction); Core Soft Skills Training; Supportive Services; and Career Guidance. Environment: For nearly 20 years of operation, OAI has created an environment conducive to collaboration among consortia members. The program has invested in classroom and hands-on training facilities and an array of resources, which can be accessed by consortia trainers and personnel during the five-year grant period.", "keywords": [ "Address", "Adult", "African American", "Age", "Area", "Automobile Driving", "Awareness", "Boat", "Case Management", "Chicago", "Cities", "Climate", "Collaborations", "Communities", "Community Health", "Computer Literacy", "Custom", "Decision Making", "Disadvantaged", "Education", "Educational Curriculum", "Emergency Situation", "Employment", "Environment", "Equipment", "Evaluation", "Evaluation Studies", "Event", "Exposure to", "Face", "Family", "First Aid", "Gases", "Goals", "Grant", "Hazardous Substances", "Hazardous Waste", "Hazardous Waste Operations and Emergency Response", "Health", "Health Hazards", "Healthy People 2020", "Hispanics", "Hour", "Human", "Human Resources", "Impact evaluation", "Industry", "Instruction", "Interview", "Kansas", "Kentucky", "Knowledge", "Law Enforcement", "Leadership", "Learning", "Life", "Mentors", "Methamphetamine Lab", "Midwestern United States", "Mission", "Modeling", "Nail plate", "National Institute of Environmental Health Sciences", "Occupations", "Oils", "Participant", "Personal Behavior", "Petroleum", "Physical environment", "Population", "Positioning Attribute", "Prevention", "Process", "Public Health", "Recycling", "Refuse Disposal", "Resources", "Risk", "Rural", "Safety", "Services", "Site", "Social Environment", "Son of Sevenless Proteins", "Student Dropouts", "Students", "Target Populations", "Trainers Training", "Training", "Training Programs", "Transportation", "Underemployment", "Unemployment", "Veterans", "Vocational Guidance", "Water", "Woman", "Work", "Workforce Development", "Workplace", "Writing", "base", "bilingualism", "building materials", "career", "climate change", "cultural competence", "design", "economic impact", "experience", "fire prevention", "first responder", "follow-up", "gulf coast", "hazard", "health disparity", "high school", "innovation", "interest", "job market", "literacy", "member", "metropolitan", "offender", "operation", "outreach", "peer", "programs", "recruit", "resilience", "retention rate", "risk minimization", "skills", "skills training", "social", "social media", "volunteer" ], "approved": true } } ], "meta": { "pagination": { "page": 1385, "pages": 1397, "count": 13961 } } }