Grant List
Represents Grant table in the DB
GET /v1/grants?page%5Bnumber%5D=1384&sort=award_amount
{ "links": { "first": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1&sort=award_amount", "last": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1424&sort=award_amount", "next": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1385&sort=award_amount", "prev": "https://cic-apps.datascience.columbia.edu/v1/grants?page%5Bnumber%5D=1383&sort=award_amount" }, "data": [ { "type": "Grant", "id": "8742", "attributes": { "award_id": "1G20AI167405-01", "title": "Upgrading the University of Pittsburgh Regional Biocontainment Laboratory within The Center for Vaccine Research", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 24445, "first_name": "Nancy G.", "last_name": "Boyd", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2021-09-23", "end_date": "2023-02-28", "award_amount": 3330000, "principal_investigator": { "id": 7425, "first_name": "William Paul", "last_name": "Duprex", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 848, "ror": "", "name": "UNIVERSITY OF PITTSBURGH AT PITTSBURGH", "address": "", "city": "", "state": "PA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 848, "ror": "", "name": "UNIVERSITY OF PITTSBURGH AT PITTSBURGH", "address": "", "city": "", "state": "PA", "zip": "", "country": "United States", "approved": true }, "abstract": "PROJECT SUMMARY/ABSTRACT: This moment in human history is precisely why the biocontainment facilities in the Center for Vaccine Research (CVR) at the University of Pittsburgh exist and why the integral Regional Biocontainment Laboratory (RBL) should be staffed with creative, funded infection biologists. The COVID-19 pandemic demonstrates the vital need to maintain such response-ready biocontainment facilities that support a diversity of researchers who can collectively pivot to address emerging infectious disease and biodefense threats of global importance. Infectious diseases have, do and will continue to emerge from animal reservoirs. In responding so effectively to work on severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 in 2020 the Pittsburgh RBL community simply and effectively fulfilled its mandated role. Establishment of a network of RBL and national biocontainment laboratories (NBLs) demonstrated prescience on the part of NIAID and the United States Government. The RBL at Pittsburgh has been used for nearly fifteen years and key core systems are coming to the end of their operational lifespan. This application seeks to upgrade i) fixed equipment, ii) non-fixed cutting-edge scientific equipment and iii) non-fixed support equipment in the RBL that are critically important to this essential facility for infection biologists across the university. A complete upgrade of building automation system (BAS) and autoclave capabilities is necessary. Cutting-edge scientific equipment will replace obsolete machines and upgrade our highly successful aerobiology unit. Biosafety cabinets (BSCs) and other important non-fixed support equipment to decontaminate the facility will be replaced. A detailed plan for phased renovations has been developed. This will be overseen by the PI and Project Manager who will work closely with external contractor, vendors and other internal groups to ensure that the scientific enterprise is not adversely impacted. Since the facility is considered essential research infrastructure the School of Medicine has committed to provide additional resources to ensure that all the necessary systems can be upgraded rather than just a partial renovation. The ultimate goal is to ensure the RBL remains fit-for-purpose and emerging infectious disease response-ready for another fifteen years.", "keywords": [ "2019-nCoV", "Address", "Animals", "Automation", "COVID-19 pandemic", "Communicable Diseases", "Communities", "Contractor", "Emerging Communicable Diseases", "Ensure", "Equipment", "Funding", "Goals", "Human", "Infection", "Laboratories", "Longevity", "National Institute of Allergy and Infectious Disease", "Phase", "Recording of previous events", "Research Infrastructure", "Research Personnel", "Resources", "Role", "State Government", "System", "United States", "Universities", "Vaccine Research", "Vendor", "Work", "biocontainment facility", "biodefense", "medical schools", "response" ], "approved": true } }, { "type": "Grant", "id": "13497", "attributes": { "award_id": "75N95023D00001-0-759502300017-1", "title": "STSS Aspire Heal Task Order 10", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Center for Advancing Translational Sciences (NCATS)" ], "program_reference_codes": [], "program_officials": [], "start_date": "2023-09-18", "end_date": "2025-09-17", "award_amount": 3347069, "principal_investigator": { "id": 29612, "first_name": "", "last_name": "", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [], "awardee_organization": { "id": 1701, "ror": "", "name": "AXLE INFORMATICS, LLC", "address": "", "city": "", "state": "MD", "zip": "", "country": "United States", "approved": true }, "abstract": "Over 25 million people in the United States experience pain every day (2012 National Health Interview Survey data) and need safe, addiction-free treatments to alleviate their suffering. This clinical demand is of tremendous importance given that overprescribing and abuse of opioids for managing acute and chronic pain has fueled the current epidemic of opioid use disorder and overdose deaths, and the effectiveness of opioids for long-term pain management is being questioned. Safe, effective, and non-addictive drugs (small molecules and biologics) to treat pain, mitigate addiction and reverse overdose are key to addressing the opioid crisis that has only worsened following the COVID-19 pandemics. Given failures and limitations of previous drug development efforts, drugs that recognize novel targets, have novel structures, and can be identified in human-based, physiologically relevant in vitro systems are needed. In 2018 NCATS by releasing NCATS ASPIRE Design Challenges, which solicited design ideas from the broader scientific community to address areas of the preclinical drug discovery process related to non-addictive pain treatment that could be accelerated by the introduction of new technologies related to: •\tIntegrated Chemistry Databases •\tElectronic Synthetic Chemistry Portals •\tPredictive Algorithms •\tBiological Assays •\tIntegrated Solutions of the above aspects In 2020, NCATS followed up with the ASPIRE Reduction-to-Practice Challenge, in which extramural researchers and innovators formed collaborative teams to deliver fully functioning prototypes of a non-addictive analgesics drug discovery platform that incorporated all the challenge topics from the design challenges (Integrated Chemistry Databases, Electronic Synthetic Chemistry Portals, Predictive Algorithms, Biological Assays). The Purdue University Team (PI: Gaurav Chopra) and the CiBots, Inc. Team (PI: Babak Esmaeli-Azad) garnered the grand prize and the runner-up prizes, respectively. We are now seeking to harness the array of technologies developed during the 2020 NCATS ASPIRE Reduction-to-Practice Challenge to build a non-traditional, merged, “super-team” of all expertise necessary to (1) complete integration of the two complementary platforms and (2) enhance the unified platform’s capability and rapidly deliver new analgesics drug candidates with safe and improved properties.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "4280", "attributes": { "award_id": "1621117", "title": "Development and Empirical Recovery for a Learning Progression-Based Assessment of the Function Concept", "funder": { "id": 3, "ror": "https://ror.org/021nxhr62", "name": "National Science Foundation", "approved": true }, "funder_divisions": [ "Education and Human Resources (EHR)", "Discovery Research K-12" ], "program_reference_codes": [], "program_officials": [ { "id": 14510, "first_name": "Finbarr", "last_name": "Sloane", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2016-09-15", "end_date": "2021-08-31", "award_amount": 3350056, "principal_investigator": { "id": 14515, "first_name": "Edith", "last_name": "Graf", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 296, "ror": "https://ror.org/03b5q4637", "name": "Educational Testing Service", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 14511, "first_name": "Robert P", "last_name": "Moses", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 14512, "first_name": "Peter W van", "last_name": "Rijn", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 14513, "first_name": "Sarah H", "last_name": "Ohls", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, { "id": 14514, "first_name": "Cheryl", "last_name": "Lizano", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 296, "ror": "https://ror.org/03b5q4637", "name": "Educational Testing Service", "address": "", "city": "", "state": "NJ", "zip": "", "country": "United States", "approved": true }, "abstract": "The project will design an assessment based on learning progressions for the concept of function. A learning progression describes how students develop understanding of a topic over time. Function is a critical concept for algebra learning and understanding. The goal of the assessment and learning progression design in this project is to specifically incorporate findings about the learning of students traditionally under-served and under-performing in algebra courses. The project will include accounting for the social and cultural experiences of the middle and high school students when creating assessment tasks. The resources developed should impact mathematics instruction (especially for algebra courses) by creating a learning progression which captures the range of student performance and appropriately places them at distinct levels of performance. The important contribution of the work is the development of a learning progression and related assessment tasks that account for the experiences of students often under-served in mathematics. The Discovery Research K-12 program (DRK-12) seeks to significantly enhance the learning and teaching of science, technology, engineering and mathematics (STEM) by preK-12 students and teachers, through research and development of innovative resources, models and tools (RMTs). Projects in the DRK-12 program build on fundamental research in STEM education and prior research and development efforts that provide theoretical and empirical justification for proposed projects.\n\nThe learning progression development will begin by comparing and integrating existing learning progressions and current research on function learning. This project will develop an assessment of student knowledge of function based on learning progressions via empirical recovery (looking for the reconstruction of theoretical levels of the learning theory). Empirical recovery is the process through which data will be collected that reconstruct the various levels, stages, or sequences of said learning progression. The development of tasks and task models will include testing computer-delivered, interactive tasks and rubrics that can be used for human and automated scoring (depending on the task). Item response theory methods will be used to evaluate the assessment tasks' incorporation of the learning progression.", "keywords": [], "approved": true } }, { "type": "Grant", "id": "7772", "attributes": { "award_id": "1U54CA260591-01", "title": "Diversity and Determinants of the Immune-Inflammatory Response to SARS-CoV-2", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Cancer Institute (NCI)" ], "program_reference_codes": [], "program_officials": [ { "id": 23577, "first_name": "CHRISTOS F", "last_name": "PATRIOTIS", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-09-30", "end_date": "2022-08-31", "award_amount": 3386294, "principal_investigator": { "id": 6204, "first_name": "Susan", "last_name": "Cheng", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 766, "ror": "https://ror.org/02pammg90", "name": "Cedars-Sinai Medical Center", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 11202, "first_name": "MICHAEL", "last_name": "KARIN", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 760, "ror": "https://ror.org/0168r3w48", "name": "University of California, San Diego", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true } ] }, { "id": 23578, "first_name": "Jane C.", "last_name": "Figueiredo", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 766, "ror": "https://ror.org/02pammg90", "name": "Cedars-Sinai Medical Center", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "ASBTRACT Overview Every day, Californians continue to experience high levels of exposure to the novel severe acute respiratory coronavirus 2 (SARS-CoV-2) virus. There is an ever-growing urgent need to better understand the nature of exposures, course of illness and recovery, and potential for immunity among persons at particularly heightened risk for the worst COVID-19 outcomes. As part of a rapid scientific response to the present public health crisis, we convened on March 18, 2020 a collaborative of frontline clinicians and scientists to form the Coronavirus Risk Associations and Longitudinal Evaluation (CORALE) studies (corale-study.org). We established two base study cohorts with enrollment centered on (i) patients with suspected or confirmed COVID-19 treated in our health system (currently N>8,300) and on (ii) healthcare workers directly or indirectly involved in delivering their care (currently N=6,679). In response to NIH RFA-CA-20-038, we are now highly motivated and prepared to leverage our existing infrastructure to directly address the critical need for comprehensive longitudinal data collection and analyses to advanced our understanding of SARS-CoV-2 risks, the course of disease, the nature of recovery, and the potential for immunity across populations at risk. By establishing the CORALE-SeroNet U54 program, our goal will be to form a robust and sustainable structure of academic activities centered on investigating the responses elicited by SARS-CoV-2 exposure and the extent to which carefully phenotyped clinical and molecular profiles can signal robust immune reconstitution and complete functional recovery. Our study will be centered on the ethnically/racially diverse population served by our health system in Los Angeles, given then critical need for more knowledge regarding the determinants of COVID-19 related risks in these minority subgroups. Our scientific objectives will be achieved by an outstanding collaborative team of clinician-scientists, epidemiologists, immunologists, basic and translational scientists, analytical chemists, and biostatisticians. Leveraging our collective experience, resources, and infrastructure at major academic institutions from across Southern California (Cedars Sinai, UCSD, UCLA, and USC), we will advance the scientific enterprise through the three distinct yet closely integrated research Projects: Project 1 will elucidate the natural history and longitudinal trajectories that represent the diversity of SARS-CoV-2 exposure, infection, recovery, and clinical immunity patterns across the spectrum of persons at risk. Project 2 will investigate the determinants of SARS-CoV-2 response in persons with altered innate immune function, with a focus on individuals with pre-infection susceptibility traits (e.g. metabolic disease states); and, Project 3 will investigate the determinants of SARS- CoV-2 response in persons with altered adaptive immune function, with a focus on individuals with immune- altered status arising from select malignancies, autoimmune disease, and/or their directed therapies. As a whole this research program will integrate population, clinical, translational, and basic science resources with a world- class investigator team to meet the urgent need for new mechanistic insights and therapeutic approaches to address key knowledge gaps regarding SARS-CoV-2 susceptibility and potential for immunity.", "keywords": [ "2019-nCoV", "Acute", "Address", "Affect", "Antibodies", "Area", "Autoimmune Diseases", "Basic Science", "COVID-19", "California", "Caring", "Characteristics", "Chronic Disease", "Clinical", "Clinical Sciences", "Cohort Studies", "Collaborations", "Communities", "Coronavirus", "Data", "Data Analyses", "Data Collection", "Disease", "Enrollment", "Ensure", "Epidemiologist", "Evaluation", "Evaluation Studies", "Exposure to", "Foundations", "Funding", "Goals", "Health", "Health Personnel", "Health system", "Healthcare Systems", "Home environment", "Immune", "Immunity", "Immunologist", "Individual", "Infection", "Inflammatory Response", "Infrastructure", "Institution", "Knowledge", "Los Angeles", "Malignant Neoplasms", "Metabolic Diseases", "Minority", "Molecular Profiling", "Natural History", "Nature", "Outcome", "Patients", "Pattern", "Persons", "Population Heterogeneity", "Population Sciences", "Populations at Risk", "Predisposition", "Public Health", "Publishing", "Recovery", "Recovery of Function", "Reporting", "Request for Applications", "Research", "Research Personnel", "Research Project Grants", "Resources", "Risk", "Scientific Advances and Accomplishments", "Scientist", "Seeds", "Seroprevalences", "Signal Transduction", "Structure", "Subgroup", "Techniques", "Therapeutic", "Translational Research", "Viral", "Virus", "Vulnerable Populations", "World Health Organization", "base", "biobank", "clinical phenotype", "disorder risk", "experience", "immune function", "immune reconstitution", "innate immune function", "insight", "novel", "operation", "pandemic disease", "programs", "racial and ethnic", "recruit", "respiratory", "response", "trait", "translational scientist" ], "approved": true } }, { "type": "Grant", "id": "6895", "attributes": { "award_id": "5U01AI069924-17", "title": "International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Alcohol Abuse and Alcoholism (NIAAA)" ], "program_reference_codes": [], "program_officials": [ { "id": 10295, "first_name": "Lori B.", "last_name": "Zimand", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2006-07-01", "end_date": "2026-04-30", "award_amount": 3400000, "principal_investigator": { "id": 22641, "first_name": "Mary-Ann", "last_name": "Davies", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 1520, "ror": "", "name": "UNIVERSITAT BERN", "address": "", "city": "", "state": "", "zip": "", "country": "SWITZERLAND", "approved": true } ] }, "other_investigators": [ { "id": 22642, "first_name": "Matthias", "last_name": "Egger", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 1520, "ror": "", "name": "UNIVERSITAT BERN", "address": "", "city": "", "state": "", "zip": "", "country": "SWITZERLAND", "approved": true }, "abstract": "Southern Africa is the epicenter of the HIV and tuberculosis (TB) epidemic, and South Africa is at the center of the COVID-19 pandemic in Africa. There is an urgent need for robust epidemiology and implementation science to address the interacting burdens of HIV, TB, and other (emerging) coinfections and non-communicable diseases (NCDs). The International epidemiology Databases to Evaluate AIDS in Southern Africa (IeDEA-SA) has defined six specific aims for the fourth funding period (IeDEA-SA IV): (1) to study outcomes along the continuum of HIV care in adults; (2) to study outcomes in pregnant women, infants, children, and adolescents; (3) to study NCDs, hepatitis B and sexually transmitted infections (STIs); (4) to study the clinical and public health epidemiology of TB; (5) to study cancer prevention, burden, and care; and (6) to study mental health and substance use disorders. Further, we defined six cross-cutting themes: (i) the impact of the COVID-19 pandemic on health services; (ii) gender equity; (iii) capacity building; (iv) digital transformation; (v) open science; and (vi) the United Nations Sustainable Development Goals, which we will develop and prioritize within each aim. Innovations include the addition of the Western Cape Provincial Health Data Centre (WC PHDC), the South African HIV Cancer Match study, the establishment of pre-Exposure prophylaxis cohorts, and the evaluation of novel technologies (for example, a point-of-care genome-sequencing device, a hand-held colposcopic device for cervical cancer screening, or tools to study the transmission of TB in the health care setting) and novel statistical and mathematical modeling approaches. Multiregional Sentinel Research Networks (NCD-Sentinel Research Network [SRN], TB-SRN, Adolescent and Young Adult Network of IeDEA) on NCDs, TB, and adolescents and youth will harmonize data collection across the six IeDEA regions in low- and middle-income countries. The Fogarty-IeDEA Mentorship Program will strengthen capacity building among early-stage investigators. IeDEA-SA now follows nearly 1.3 million people living with HIV, including 285,000 individuals from the private sector (the Aid for AIDS program AfA), and 370,000 with ART duration > ten years. IeDEA IV will add data from 600,000 HIV-negative people through AfA and information from up to 4 million HIV-negative individuals from the WC PHDC in specific analyses. Within IeDEA, the Southern African region includes by far the largest number of adults and children. The COVID-19 pandemic now highlights the importance of epidemiologic research and implementation science across the health system. IeDEA-SA is well- placed to address the specific aims and cross-cutting themes outlined in this application, through its successful track-record of collaboration between the scientific and operational leadership at the Universities of Bern and Cape Town, partnership with several African universities (including the Kwazulu-Natal Research Innovation and Sequencing Platform), United States and European universities, and with the World Health Organization and the Joint United Nations Programme on HIV/AIDS.", "keywords": [ "2019-nCoV", "AIDS/HIV problem", "Acquired Immunodeficiency Syndrome", "Address", "Adolescent", "Adolescent and Young Adult", "Adult", "Adverse event", "Affect", "Africa", "Africa South of the Sahara", "African", "Anti-Retroviral Agents", "Breast Feeding", "COVID-19", "COVID-19 pandemic", "Caring", "Cervical Cancer Screening", "Child", "Clinical", "Collaborations", "Data", "Data Collection", "Data Linkages", "Databases", "Devices", "Diagnosis", "Diagnostic", "Disease", "Drug resistance", "Drug resistance in tuberculosis", "Epidemic", "Epidemiology", "European", "Evaluation", "Funding", "Goals", "HIV", "HIV Seronegativity", "HIV/TB", "Hand", "Health", "Health Services", "Health care facility", "Health system", "Hepatitis B", "Hepatitis B Virus", "Incidence", "Individual", "Infant", "Infection", "International", "Joints", "Leadership", "Life Cycle Stages", "Life Expectancy", "Liver", "Lung diseases", "Malignant Neoplasms", "Mental Health", "Mentorship", "Metabolic", "Methods", "Modeling", "Monitor", "Outcome", "Outcome Study", "Output", "Persons", "Pharmaceutical Preparations", "Policies", "Pregnant Women", "Prevalence Study", "Prevention", "Prevention program", "Prevention strategy", "Private Sector", "Public Health", "Pulmonary Tuberculosis", "Quality of life", "Regimen", "Registries", "Research", "Research Personnel", "Resistance", "Risk", "Risk Factors", "SARS-CoV-2 transmission", "Safety", "Sentinel", "Services", "Sexually Transmitted Diseases", "South Africa", "South African", "Southern Africa", "Sputum", "Statistical Models", "Substance Use Disorder", "Sustainable Development", "Time", "Translating", "Treatment outcome", "Tuberculosis", "United Nations", "United States", "Universities", "Viral", "Woman", "Work", "World Health Organization", "antiretroviral therapy", "base", "cancer care", "cancer diagnosis", "cancer health disparity", "cancer prevention", "cardiometabolic risk", "cervical cancer prevention", "co-infection", "cohort", "cost effective", "data centers", "data harmonization", "digital", "efavirenz", "epidemiology study", "gender equity", "genome sequencing", "health care settings", "health data", "implementation science", "improved", "improved outcome", "in utero", "innovation", "low and middle-income countries", "mathematical model", "mortality", "negative affect", "new technology", "novel", "open data", "point of care", "pre-exposure prophylaxis", "prevent", "programs", "resi" ], "approved": true } }, { "type": "Grant", "id": "9245", "attributes": { "award_id": "3U54MD007601-34S2", "title": "Community Driven Approach to Mitigate COVID 19 Disparities in Hawaii's Vulnerable Populations", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 7638, "first_name": "Richard", "last_name": "Berzon", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-09-22", "end_date": "2023-06-30", "award_amount": 3400883, "principal_investigator": { "id": 22820, "first_name": "Jerris Robert", "last_name": "Hedges", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 866, "ror": "https://ror.org/01wspgy28", "name": "University of Hawaii at Manoa", "address": "", "city": "", "state": "HI", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 22821, "first_name": "Noreen", "last_name": "Mokuau", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 866, "ror": "https://ror.org/01wspgy28", "name": "University of Hawaii at Manoa", "address": "", "city": "", "state": "HI", "zip": "", "country": "United States", "approved": true }, "abstract": "The long-term goal of this proposal is to eliminate COVID-19 disparities among Hawaii’s racial/ethnically diverse yet vulnerable populations including Native Hawaiian and other Pacific Islanders (NHPI) living in rural and underserved communities by integrating innovative SARS-CoV-2 testing capacity with novel community-specific messaging and education. Compounded by long-standing health disparities and socioeconomic challenges, NHPIs suffer from increased infection and mortality rates attributed to COVID-19. To date, NHPIs rank among the highest disproportionately burdened by SARS-CoV-2 in the U.S. With the nation’s highest Rt, a basic reproductive metric indicating the degree of viral spread, Hawaii’s disaggregated NHPI data reveal further disparities. Preliminary testing data collected by our partner, the Waianae Coast Comprehensive Health Center (WCCHC), Hawaii’s largest federally funded community health center, indicates a significant deficiency in testing uptake, especially among Pacific Islanders. Further, we observed under-representative coverage of testing among youth (ages 5-19 years old) in NHPI communities, despite their higher than average infection rate. Other factors, including slow testing turnaround time and untested asymptomatic cases, complicate efforts to contain further community spread. Given the looming public health concerns around re-opening businesses and schools, these gaps highlight the critical need for innovative approaches of effecting behavioral change coupled with novel testing strategies to enhance access to all community members, including school-aged children/youth. Fortunately, our partnerships in Hawaii’s culturally diverse populations offer a unique opportunity to augment the current COVID-19 response with community knowledge and resilience. We propose the hypothesis that community-contextualized messaging disseminated by novel healthcare-school partnerships coupled with a robust community and patient-centered testing strategy will increase reach, access, uptake, and impact for COVID-19 testing in vulnerable populations. To test this hypothesis, our multidisciplinary team aims to (1) evaluate SARS-CoV-2 testing data, identify gaps and barriers in testing, and augment community testing capacity to increase uptake and (2) optimize and implement community-informed COVID-19 messaging and education with a novel community healthcare-school network partnership in the NHPI population across Hawaii. Building on our parent “Ola HAWAII” grant, this project leverages our existing Community Engagement, Biostatistics, and Administrative Cores with NHPI partnerships to augment the RADx-UP Coordinating and Data Collection Center for common evaluation metrics on COVID-19 testing-related outcomes and implementation. This will lay the foundation for an engaged community network primed for disseminating anticipated vaccines in Hawaii’s highest risk populations. Given the urgency to both improve public health safety and re-opening schools, results from this project may offer insights into an integrated model or toolkit from which health clinics and schools in underserved & vulnerable communities across the country might actively participate in abating this pandemic.", "keywords": [ "19 year old", "2019-nCoV", "Abate", "Address", "Age", "Behavior", "Behavioral", "Biometry", "Businesses", "COVID-19", "Caring", "Child", "Chronic", "Clinic", "Collaborations", "Communities", "Community Healthcare", "Community Networks", "Conflict (Psychology)", "Country", "Coupled", "Data", "Data Collection", "Discrimination", "Education", "Educational Curriculum", "Evaluation", "Exposure to", "FDA approved", "Family", "Filipino", "Foundations", "Fright", "Funding", "Goals", "Grant", "Growth", "Hawaii", "Health", "Health Personnel", "Health Professional", "Healthcare", "Hotlines", "Household", "Housing", "Individual", "Infection", "K-12 Education", "Knowledge", "Language", "Mission", "Modeling", "Molecular Diagnostic Testing", "Native Hawaiian", "Neighborhood Health Center", "Occupations", "Outcome", "Pacific Island Americans", "Parents", "Perception", "Physicians", "Population", "Population Heterogeneity", "Poverty", "Protocols documentation", "Public Health", "Public Health Education", "Race", "Recording of previous events", "Research", "Research Personnel", "Rural", "Rural Community", "Safety", "School-Age Population", "Schools", "Science", "Services", "Site", "Students", "Technology", "Testing", "Time", "Vaccines", "Viral", "Vulnerable Populations", "Youth", "base", "community center", "design", "ethnic disparity", "ethnic diversity", "health care availability", "health disparity", "high risk population", "improved", "infection rate", "innovation", "insight", "member", "mortality", "multidisciplinary", "novel", "outreach", "outreach program", "pandemic disease", "patient oriented", "racial and ethnic", "remote communities", "reproductive", "resilience", "response", "rural underserved", "socioeconomics", "tool", "uptake" ], "approved": true } }, { "type": "Grant", "id": "6137", "attributes": { "award_id": "3U01AI144616-03S1", "title": "Household Respiratory Virus SARS-CoV-2 Transmission and Immunity Sub-Study (HRTS)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute of Allergy and Infectious Diseases (NIAID)" ], "program_reference_codes": [], "program_officials": [ { "id": 20856, "first_name": "MICHAEL JOHN", "last_name": "Cooper", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-06-03", "end_date": "2023-04-30", "award_amount": 3407968, "principal_investigator": { "id": 20857, "first_name": "AUBREE L", "last_name": "GORDON", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] }, "other_investigators": [ { "id": 20858, "first_name": "Paul G.", "last_name": "Thomas", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 829, "ror": "https://ror.org/02r3e0967", "name": "St. Jude Children's Research Hospital", "address": "", "city": "", "state": "TN", "zip": "", "country": "United States", "approved": true }, "abstract": "The pandemic created by the novel human coronavirus SARS-CoV-2 has generated many unanswered questions on the best practices for prevention and treatment for those with COVID- 19 disease. The mechanism behind the lack of apparent disease susceptibility in children is also unresolved. To answer these most critical questions, we require data on how the host immune system responds to SARS-CoV-2 infection and COVID-19 disease. Longitudinal cohorts established in naive populations are necessary for careful profiling of immune responses, disease severity, and the generation of protective memory. Disease presentation and outcome has been highly variable among age groups and those with various underlying conditions, complicating study design. Large well-characterized human cohorts are costly to initiate and difficult to develop quickly. In this study, we propose to use the DIVINCI Consortium cohorts, three geographically distinct human birth cohorts, which are already established and successfully running to be able to immediately begin sampling individuals with suspected or confirmed SARS-CoV-2 infection. Importantly, all three cohorts have the ability to collect household samples, providing insights into immunity and disease progression across a broad age range. We propose to collect respiratory samples, breast milk, stool/rectal swab, and serum/PBMC samples, and from those samples, exhaustively assay the host immune response to SARS-CoV-2. Based on the study design, we will be able to compare naive time points to those during active infection as well as samples from individuals who remained asymptomatic compared to those who develop varying degrees of symptoms. Our study proposes to comprehensively measure immune cell populations in the peripheral blood in naive (baseline) samples and convalescent samples (after infection.) We propose to develop novel reagents for measuring SARS-CoV-2-specific T and B cells. Further, we propose to measure SARS-CoV-2 viral diversity and evolution. Finally, we will be able to extensively assay serological samples to determine measurable differences in the response between individuals with mild and severe infection and asymptomatic and symptomatic infection, and track their subsequent susceptibility to re-infection. The DIVINCI consortium is uniquely situated to have immediate response to the SARS-CoV-2 pandemic with the ultimate goal of a more complete understanding of the virus and the disease.", "keywords": [ "2019-nCoV", "Age", "B-Lymphocytes", "Biological Assay", "Birth", "COVID-19", "COVID-19 pandemic", "Cells", "Child", "Data", "Disease", "Disease Progression", "Disease susceptibility", "Evolution", "Feces", "Generations", "Geography", "Goals", "Household", "Human", "Human Milk", "Immune", "Immune response", "Immune system", "Immunity", "Individual", "Infection", "Longitudinal cohort", "Measurable", "Measures", "Memory", "Outcome", "Peripheral Blood Mononuclear Cell", "Population", "Predisposition", "Prevention", "Reagent", "Research Design", "Running", "SARS-CoV-2 infection", "SARS-CoV-2 transmission", "Sampling", "Serology test", "Serum", "Severity of illness", "Swab", "Symptoms", "T-Lymphocyte", "Time", "Viral", "Virus Diseases", "age group", "base", "cohort", "cost", "exhaustion", "human coronavirus", "insight", "novel", "pandemic disease", "peripheral blood", "rectal", "respiratory", "respiratory virus", "response" ], "approved": true } }, { "type": "Grant", "id": "12367", "attributes": { "award_id": "1R56AG079510-01A1", "title": "Asian Americans & Racism: Individual and Structural Experiences (ARISE)", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "National Institute on Aging (NIA)" ], "program_reference_codes": [], "program_officials": [ { "id": 20528, "first_name": "FRANK", "last_name": "Bandiera", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2023-09-21", "end_date": "2024-08-31", "award_amount": 3432146, "principal_investigator": { "id": 20504, "first_name": "Van My Ta", "last_name": "Park", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 768, "ror": "https://ror.org/043mz5j54", "name": "University of California, San Francisco", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 768, "ror": "https://ror.org/043mz5j54", "name": "University of California, San Francisco", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "Problem-free”, “perpetual foreigner”, “silent minority”, “all the same” – these are stereotypes that have long plagued Asian Americans (ASAs), often referred to as the “model minority”. ASAs, however, encompasses a diversity of cultures, languages, immigration experiences, socioeconomic status (SES), and religions. Racism and discrimination against ASAs are not new but resurfaced with new intensity during the COVID-19 pandemic. Individual and area level racism and discrimination are tied to significant health disparities that influence risk of Alzheimer’s Disease and Related Dementias (ADRD). For ASAs, racism and discrimination at the individual and area level (e.g., residential segregation; redlining) may result in potential cognitive health disparities; however, this area of research in ASAs is understudied. Limited research suggests that at least some ASA groups have lower ADRD risk than non-Hispanic White individuals. Identification of potential protective factors (e.g., family cohesion) that may mitigate racism-related risk is an important scientific opportunity. Studies examining the role of multi-level discrimination related to ASAs’ risk for ADRD are sorely needed but limited. Our proposed study, Asian Americans & Racism: Individual and Structural Experiences (ARISE), guided by the NIA health disparities framework, will develop a multi-site, multi-lingual cohort in California to study the prevalence as well as the impact of multi-level discrimination and resilience resources on associated risk for ADRD among 1,500 older (≥65 years old) Chinese, Korean, and Vietnamese Americans. We will leverage PI Park’s NIA-funded Collaborative Approach for AAPI Research and Education (CARE) registry as one of our recruitment sources. Our specific aims include: 1) Establish the ARISE cohort to determine the prevalence of life course experiences of multi-level discrimination among older Chinese-, Korean-, and Vietnamese Americans; 2) Evaluate the association of multi-level discrimination on cognitive performance and levels of AD biomarkers, overall and by ASA subgroup, sex, and primary language among ARISE participants. Secondary/exploratory Aim: Evaluate the association between multi-level discrimination and cognitive decline; and 3) Evaluate protective and risk factors that modify the effects of multi-level discrimination on cognitive performance and levels of AD biomarkers among ARISE participants. The scientific promise of ARISE is timely and necessary. The COVID-19 pandemic has exposed and exacerbated anti-Asian racism. ARISE will add to our limited understanding of ASAs who are under-represented and under-engaged in ADRD and aging research.", "keywords": [ "Aging", "Alcohol consumption", "Alzheimer&apos", "s Disease", "Alzheimer&apos", "s disease related dementia", "Alzheimer&apos", "s disease risk", "American", "Area", "Asian Americans", "Biological Markers", "Blood", "Buffers", "COVID-19 pandemic", "California", "Chinese", "Chronic", "Clinical", "Cognition", "Cognitive", "Communities", "Data", "Data Analyses", "Data Collection", "Databases", "Diabetes Mellitus", "Discrimination", "Education", "Family", "Foreigner", "Frequencies", "Functional disorder", "Funding", "Future", "Glial Fibrillary Acidic Protein", "Health", "Hypertension", "Immigrant", "Immigration", "Impaired cognition", "Individual", "Koreans", "Language", "Life Cycle Stages", "Light", "Memory", "Mental Depression", "Minority", "Modeling", "Multilingualism", "Neighborhoods", "Not Hispanic or Latino", "Obesity", "Outcome", "Pacific Islander", "Participant", "Prejudice", "Prevalence", "Prevalence Study", "Race", "Recording of previous events", "Registries", "Religion", "Religion and Spirituality", "Reporting", "Research", "Resources", "Respondent", "Risk", "Risk Factors", "Role", "Severities", "Site", "Smoking", "Social support", "Socioeconomic Status", "Source", "Stereotyping", "Subgroup", "Surface", "Surveys", "United States", "Vietnamese", "Visit", "anti-Asian", "cardiometabolic risk", "cardiometabolism", "cognitive performance", "cognitive testing", "cohesion", "cohort", "collaborative approach", "dementia risk", "executive function", "experience", "follow-up", "hate crimes", "health disparity", "health inequalities", "human old age (65+)", "neurofilament", "pandemic disease", "perceived discrimination", "physical inactivity", "protective factors", "racial bias", "racial population", "racism", "recruit", "residential segregation", "resilience", "sex", "social determinants", "sociodemographics", "tau Proteins", "tau-1" ], "approved": true } }, { "type": "Grant", "id": "9217", "attributes": { "award_id": "3P50CA244433-02S1", "title": "Implementation Science Center in Cancer Control Equity: A Competitive Revision to Accelerate COVID Testing in Vulnerable Communities", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 24954, "first_name": "HEATHER", "last_name": "D'Angelo", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-09-01", "end_date": "2023-08-31", "award_amount": 3432338, "principal_investigator": { "id": 24955, "first_name": "Susan", "last_name": "Dargon-Hart", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 961, "ror": "", "name": "HARVARD SCHOOL OF PUBLIC HEALTH", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [ { "id": 21710, "first_name": "Karen M.", "last_name": "Emmons", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 961, "ror": "", "name": "HARVARD SCHOOL OF PUBLIC HEALTH", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true } ] }, { "id": 21711, "first_name": "Elsie Mireya", "last_name": "Taveras Benavidez", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "awardee_organization": { "id": 961, "ror": "", "name": "HARVARD SCHOOL OF PUBLIC HEALTH", "address": "", "city": "", "state": "MA", "zip": "", "country": "United States", "approved": true }, "abstract": "This competitive revision submitted to the RADx-UP Initiative (NOT-20-121) aims to extend the infrastructure of our P50 Implementation Science Center for Cancer Control Equity (ISCCCE) to accelerate COVID testing in 9 hotspot communities in MA. ISCCCE is a strong partnership with the Massachusetts League of Community Health Centers, in which we co-design studies to increase implementation of evidence-based practices focused on equity. Together we are extremely well-positioned to extend our community-engaged efforts to COVID-19 testing, and to build an infrastructure that will support future COVID-related mitigation and prevention efforts in the vulnerable communities that our community health centers (CHCs) serve. This project will include 6 community health center- community partnerships in nine vulnerable communities that continue to be COVID hot spots. These communities collectively have 1.3 million residents. Partner CHCs currently focus on COVID-19 testing for diagnostic purposes in symptomatic individuals, with limited outreach testing in high-risk communities. This project will expand the scope of testing to include prospective surveillance activities using dedicated testing and outreach teams. Accelerated testing efforts will be focused on CHC patients and community members who have significant social and medical vulnerabilities to COVID, per the NOSI, including those living in congregate housing, people experiencing homelessness, those with substance use disorders, low wage essential workers, and those with limited English proficiency. The partnership is well- integrated into the State’s testing and contact tracing strategy, and well-positioned to leverage those resources. We draw on our strongly community-engaged, equity-focused approach to implementation, and on Mass League’s extensive experience in HIV testing and contact tracing. We will use an interrupted time series design to evaluate the impact of the enhanced outreach efforts on testing rates overall and on priority populations in the context of different phases of re-opening and restrictions. We will also use an exploratory sequential mixed methods approach to conduct a series of community- engaged pilot studies to address key barriers to testing and different approaches to return of results. Our Human Participant Research Unit, co-led by academic and community-based investigators, will guide the partnership’s work through an ethics and equity lens. We will support the CHC-community partnerships through our Testing Capacity and Innovation Team, which will provide infectious disease expertise and technical guidance on COVID testing. Our Community Communications Team will use educational and communication design strategies to develop culturally and linguistically appropriate materials to support the testing activities.", "keywords": [ "Address", "COVID-19", "Cancer Center", "Cancer Control", "Collaborations", "Communicable Diseases", "Communication", "Communities", "Contact Tracing", "Diagnostic tests", "Ethics", "Evidence based practice", "Future", "Homelessness", "Hot Spot", "Housing", "Human", "Human immunodeficiency virus test", "Individual", "Infrastructure", "Interruption", "Laboratories", "Limited English Proficiency", "Linguistics", "Massachusetts", "Medical", "Methods", "Monitor", "Neighborhood Health Center", "Participant", "Patients", "Phase", "Pilot Projects", "Population", "Positioning Attribute", "Prevention", "Research", "Research Design", "Research Personnel", "Resources", "Series", "Substance Use Disorder", "Testing", "Time", "Underserved Population", "Vulnerable Populations", "Wages", "Work", "base", "community partnership", "coronavirus disease", "design", "experience", "high risk", "implementation science", "innovation", "lens", "member", "outreach", "patient oriented", "prospective", "social" ], "approved": true } }, { "type": "Grant", "id": "9351", "attributes": { "award_id": "3P30AI027763-29S1", "title": "Collaborative community networks to optimize implementation of low barrier COVID-19 testing efforts among diverse Latinx populations in Northern California", "funder": { "id": 4, "ror": "https://ror.org/01cwqze88", "name": "National Institutes of Health", "approved": true }, "funder_divisions": [ "NIH Office of the Director" ], "program_reference_codes": [], "program_officials": [ { "id": 13099, "first_name": "Eric William", "last_name": "Refsland", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [] } ], "start_date": "2020-10-21", "end_date": "2022-08-31", "award_amount": 3432455, "principal_investigator": { "id": 10026, "first_name": "Monica", "last_name": "Gandhi", "orcid": null, "emails": "", "private_emails": "", "keywords": null, "approved": true, "websites": null, "desired_collaboration": null, "comments": null, "affiliations": [ { "id": 768, "ror": "https://ror.org/043mz5j54", "name": "University of California, San Francisco", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true } ] }, "other_investigators": [], "awardee_organization": { "id": 768, "ror": "https://ror.org/043mz5j54", "name": "University of California, San Francisco", "address": "", "city": "", "state": "CA", "zip": "", "country": "United States", "approved": true }, "abstract": "Modified Project Summary/Abstract Section The health and economic effects of the COVID-19 pandemic in the United States are staggering, and persons of color in the US – already heavily impacted by structural inequities – bear a disproportionate burden of COVID-19 disease and death. Testing is a cornerstone of stopping the spread of the virus, yet in the US testing rates remain far below target levels and current strategies are failing to reach the communities most affected. In California, despite initial success in limiting spread with the earliest shelter-in-place mandate in the nation, even partial attempts at easing restrictions have resulted in a surge in new cases. Currently, California has the highest case count in the U.S and the pandemic is taking a disproportionate toll on Latinx individuals, many of whom are essential workers. An incomplete understanding of testing barriers and optimal strategies to mitigate these barriers among Latinx persons hampers the design of the scalable strategies needed to accelerate equity in the reach, uptake, and preventative impact of SARS CoV-2 testing throughout the US. In this proposal, our objective is to evaluate community-engaged approaches to scale low-barrier COVID-19 testing for Latinx communities and evaluate retesting strategies for priority groups in Latinx communities at increased risk of infection. We will draw upon our experience with Latinx community-engaged mass SARS-CoV2 testing campaigns, expertise in community-based HIV testing strategies informed by behavioral economics and the success of San Francisco’s Latinx Task Force for COVID-19 model. In Aim 1, we will evaluate implementation of a Latino Task Force (LTF) collaborative network across 3 counties in Northern California (Marin, Merced and San Francisco), adapted from San Francisco’s LTF model to promote locally-adapted COVID-19 test and respond initiatives in two majority-Latinx communities: one suburban (Marin) and one rural (Merced). In Aim 2, we will determine the population-level prevalence of active (PCR+) SARS-CoV-2 infection, most at-risk subgroups, and attitudes and preferences of community members regarding COVID-19 testing services during baseline mass testing campaigns at the Marin and Merced sites. The campaigns will offer testing to all community residents regardless of symptoms at easily accessible venues, implemented in partnership with each site’s LTF. In Aim 3, we will evaluate implementation of three, complementary community-responsive COVID-19 testing strategies, delivered by local community health workers (“promotoras”) and tailored to the needs of the two study communities post-COVID-19 vaccine scale-up in Northern California. These three strategies include a) community-based, drop-in testing sites outside of daytime work hours, b) as needed testing responsive to community member needs (outside of drop-in testing) and c) spot surveillance provision for local businesses and organizations. The proposed research will provide critical data to inform scalable testing strategies, reduce transmission, decrease health disparities, and set the stage for future, biomedical interventions, such as vaccines.", "keywords": [ "2019-nCoV", "Adoption", "Adult", "Advisory Committees", "Affect", "African American", "Altruism", "Antibodies", "Attitude", "Automobile Driving", "Behavioral", "Businesses", "COVID-19", "COVID-19 pandemic", "COVID-19 test", "COVID-19 testing", "COVID-19 vaccine", "California", "Censuses", "Cessation of life", "Color", "Communities", "Community Health Aides", "Community Networks", "County", "Data", "Decision Making", "Disease", "Drops", "Economics", "Effectiveness", "Epidemiology", "Evaluation", "Family health status", "Future", "Health system", "Hispanics", "Home", "Hour", "Human immunodeficiency virus test", "Immigration", "Improve Access", "Incentives", "Income", "Individual", "Infection", "Intervention", "Language", "Latino", "Latinx", "Low income", "Maintenance", "Modeling", "Persons", "Population", "Prevalence", "Prevention", "Randomized", "Randomized Controlled Trials", "Reach Effectiveness Adoption Implementation and Maintenance", "Reproducibility", "Research", "Risk", "Risk Factors", "Role", "Rural", "SARS-CoV-2 infection", "Sampling", "San Francisco", "Shelter facility", "Site", "Spottings", "Structure", "Subgroup", "Symptoms", "Testing", "Unemployment", "United States", "Ursidae Family", "Vaccines", "Virus", "Work", "Workplace", "arm", "base", "behavioral economics", "community engaged research", "community setting", "comparative effectiveness", "cost", "design", "distrust", "ethnic disparity", "experience", "financial incentive", "follow-up", "health disparity", "health economics", "health inequalities", "implementation outcomes", "infection risk", "innovation", "insight", "member", "motivated behavior", "pandemic disease", "preference", "primary outcome", "scale up", "standard care", "suburb", "success", "testing access", "testing services", "testing uptake", "theories", "transmission process", "underserved community", "uptake", "vaccine delivery" ], "approved": true } } ], "meta": { "pagination": { "page": 1384, "pages": 1424, "count": 14236 } } }